Protein

Protein accession
A0A0H4SQ70 [UniProt]
Representative
8lv7R
Source
UniProt (cluster: phalp2_40143)
Protein name
Lysozyme 1
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MQSIDFGRALDFTLRWEGGYVNHPSDPGGATNRGITQVTYNQWRTQKGLPTREVRLIEEDEVRSIYWQFYWAPVEGRTAPSWVQFRVCLFDTFVQFGVFGGTFLWQKVCGVPADGQWGPVTSRATENLVSTKGPLWSGMALVGERVRYRAQRVSQNRSQLAFLQGWLNRDSDLLLYLLNLR
Physico‐chemical
properties
protein length:181 AA
molecular weight:20811,3 Da
isoelectric point:9,34
hydropathy:-0,35
Representative Protein Details
Accession
8lv7R
Protein name
8lv7R
Sequence length
192 AA
Molecular weight
22440,31020 Da
Isoelectric point
6,97786
Sequence
MSHNKVYELALNFTLKWEGLPSKYAQKRGRATKYGIDQETYDECYTLGLVPKKDIAHITYEEAERVYFYKYWRHMGRFTSMTWYEFQVTLFDTFVQFDVPGGIAIWQRALGVREDGIWGPATERATWAYIEKRGSLGGALKLIAERMRHRPQQAKEDGSQGLSLRGLIKRDLELIEYVFEIHELAQAFELPS
Other Proteins in cluster: phalp2_40143
Total (incl. this protein): 3 Avg length: 186,7 Avg pI: 8,45
Protein ID Length (AA) pI
8lv7R 192 6,97786
8lv7Q 187 9,04164
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_23908
1Le4q
 257 30,0% 173 1.409E-33
2 phalp2_29938
8lh6b
 3 29,4% 187 2.904E-31
3 phalp2_37851
4LyyS
 5845 29,0% 165 2.542E-27
4 phalp2_18877
1MrjM
 564 28,1% 167 2.267E-26
5 phalp2_30515
5lEwY
 188 27,3% 168 3.351E-24
6 phalp2_1444
1DO8y
 138 31,2% 173 5.547E-23
7 phalp2_13016
426A1
 31 30,9% 165 2.634E-22
8 phalp2_28839
4XJZ6
 27 26,9% 171 3.597E-22
9 phalp2_12946
360Ik
 1926 24,3% 164 3.597E-22
10 phalp2_12184
6C2VC
 988 26,0% 169 1.250E-21

Domains

Domains [InterPro]
GH108
Representative sequence (used for alignment): 8lv7R (192 AA)
Member sequence: A0A0H4SQ70 (181 AA)
1 192 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05838

Taxonomy

  Name Taxonomy ID Lineage
Phage Cyanophage cp-OS
[NCBI] 		1679405 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KR259643 [NCBI]
CDS location
range 1 -> >543
strand +
CDS
ATGCAGAGTATCGACTTCGGTCGTGCGCTGGACTTCACCCTGCGTTGGGAAGGCGGTTACGTTAACCACCCGTCTGACCCTGGCGGTGCTACGAACCGTGGTATCACCCAGGTTACCTACAACCAGTGGCGTACCCAGAAAGGTCTGCCGACGCGTGAAGTTCGTCTGATCGAAGAAGACGAGGTTCGCTCTATCTACTGGCAGTTCTATTGGGCGCCAGTTGAAGGTCGTACCGCGCCTTCTTGGGTTCAGTTCCGTGTTTGCCTGTTCGACACCTTCGTACAGTTCGGTGTTTTCGGTGGTACCTTCCTGTGGCAGAAAGTTTGCGGTGTTCCGGCGGACGGTCAGTGGGGTCCGGTTACTTCTCGTGCCACCGAGAACCTGGTTTCTACCAAAGGTCCGCTGTGGTCTGGTATGGCGCTGGTTGGTGAACGTGTTCGTTACCGTGCGCAGCGTGTTTCTCAGAACCGTTCTCAGCTGGCGTTCCTCCAGGGCTGGCTGAATCGTGATTCTGATCTGCTGCTGTACCTGCTGAACCTGCGT

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. N/A UniProt

Tertiary structure

PDB ID
upi00065f5aa0_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (8lv7R) rather than this protein.
PDB ID
8lv7R
Method AlphaFoldv2
Resolution 86.65
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50