Protein

Protein accession
A0AAX4QF37 [UniProt]
Representative
8ehcj
Source
UniProt (cluster: phalp2_10539)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKTSTRGLMALIAHEGIVLSRYKDSVGVWTIGVGHTKAAGGLNPEIFSGTLTIRQVMEMLREDIVKYENGVNKAVKVPLKQHEFDALVSFHYNTGAIGRASFVKALNAGDRAAAYRGIMDWKKPPEIIPRRTAERDLLRDGAYPAPFATVYPATPSGSVQWGKGQRVNLSDLMAEHFVTDDPGPKPKPASGGNWLAVLIEAIANAFRGGK
Physico‐chemical
properties
protein length:210 AA
molecular weight:22784,9 Da
isoelectric point:9,63
hydropathy:-0,22
Representative Protein Details
Accession
8ehcj
Protein name
8ehcj
Sequence length
298 AA
Molecular weight
31441,41940 Da
Isoelectric point
7,93111
Sequence
MSVSRMGLAEIISDEAIVTSPYFDSVGVLTDGVGHTAKAGGHDPAKLPKGVPIPIPEIIATFRKDVRKFNDRVNKAVTRKMAQHEEDAFTKFDFNTGGINRATAVTAFNAGDRAKAADLLMNWRKPPEIIPRRRREQKLLRDGVYSSGGMANVYPADTRGRVLWKRGKRINVLPIIDNLFAANAADDKAAADGKKAVGAGGGTLITGGGSTQAPDISQLPNDAGTLHLFLIAVAVVLGAIALVFIIGAIRHRLAAKANEDAAVAKVTAELEAAAEGSAPVPDHITDPDVDPASGETQE
Other Proteins in cluster: phalp2_10539
Total (incl. this protein): 2 Avg length: 254,0 Avg pI: 8,78
Protein ID Length (AA) pI
8ehcj 298 7,93111
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_29634
8aoUy
 1 27,2% 257 2.009E-11

Domains

Domains [InterPro]
GH24
Representative sequence (used for alignment): 8ehcj (298 AA)
Member sequence: A0AAX4QF37 (210 AA)
1 298 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Microcystis phage Mwe-JY13
[NCBI] 		3128147 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP438406 [NCBI]
CDS location
range 17918 -> 18550
strand +
CDS
ATGAAAACCAGCACACGCGGCCTAATGGCCCTGATCGCACATGAGGGAATCGTCCTGTCCCGTTACAAGGACAGCGTAGGAGTCTGGACTATTGGTGTCGGCCACACAAAAGCTGCTGGCGGTCTGAATCCTGAGATATTTTCCGGCACGCTGACCATTCGTCAGGTTATGGAAATGCTGCGTGAGGACATAGTCAAGTACGAGAACGGCGTTAATAAAGCCGTGAAGGTTCCGCTTAAACAGCATGAGTTCGATGCGCTTGTTTCTTTCCATTACAACACTGGCGCAATCGGCAGGGCGTCCTTCGTCAAGGCTCTGAATGCTGGCGACCGTGCTGCTGCATATCGCGGCATTATGGACTGGAAAAAGCCGCCTGAGATTATCCCGCGCCGCACCGCTGAGAGGGATCTGTTGCGGGATGGCGCTTACCCTGCGCCGTTCGCAACGGTCTACCCAGCAACGCCTAGCGGGTCTGTGCAATGGGGCAAGGGGCAGCGGGTTAACCTGTCTGACCTGATGGCAGAGCATTTCGTCACAGACGACCCAGGGCCGAAGCCCAAGCCAGCATCTGGCGGCAATTGGCTTGCCGTTCTAATCGAAGCCATCGCAAACGCTTTCCGAGGTGGGAAATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8ehcj) rather than this protein.
PDB ID
8ehcj
Method AlphaFoldv2
Resolution 81.47
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50