Protein

Protein accession
A0AAU0N5R6 [UniProt]
Representative
6DqiX
Source
UniProt (cluster: phalp2_24737)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MGDKATPEQCYQMTLKDYQRFERIVLDAIKVPLNVNEQTALTFFCYNVGPVCTTSTAFKRFNQGRATEGCQALAMWNKVTINGQKVVSKGLVNRRNAEIKQCLEPSSQYSSLLW
Physico‐chemical
properties
protein length:114 AA
molecular weight:12931,7 Da
isoelectric point:9,08
hydropathy:-0,35
Representative Protein Details
Accession
6DqiX
Protein name
6DqiX
Sequence length
158 AA
Molecular weight
17220,56100 Da
Isoelectric point
9,32027
Sequence
VVPYLVKDEGFVADAQGNSKPYYDAVGVLTDCFGNSGQGPYKVRLSLHRTKAECRTILAEEIERSYYGPLVARIPGFGSFPIPTQIATTRFAYNVGVEATVKGSVGQLFARGRLVEGCKAMLMYDKGTINGKKVRIKGLTTRRQAEAKQCLEGAAQHD
Other Proteins in cluster: phalp2_24737
Total (incl. this protein): 6 Avg length: 151,0 Avg pI: 8,93
Protein ID Length (AA) pI
6DqiX 158 9,32027
4muMo 169 9,36012
A0A7S5QUZ4 237 7,63850
A0A9E7QP01 114 9,09702
A0AAF0FG21 114 9,07704
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_7028
8i7gz
 89 30,3% 135 1.237E-39
2 phalp2_4305
8aoFg
 2477 38,3% 133 1.398E-37
3 phalp2_11002
4Mz75
 307 30,0% 133 2.243E-29
4 phalp2_8851
2IyxA
 73 27,9% 136 1.339E-27
5 phalp2_9410
8Hj1q
 5109 32,8% 134 5.254E-25
6 phalp2_3556
4E0oc
 53 33,8% 133 9.838E-22
7 phalp2_21319
1KsyR
 184 27,7% 144 1.346E-21
8 phalp2_33109
4K52y
 18 35,0% 154 8.838E-21
9 phalp2_34995
4LMnK
 728 27,7% 137 5.796E-20
10 phalp2_23830
1lpLy
 242 30,0% 143 2.776E-19

Domains

Domains [InterPro]
GH24
Representative sequence (used for alignment): 6DqiX (158 AA)
Member sequence: A0AAU0N5R6 (114 AA)
1 158 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Pseudomonas phage vB_PaPhi_Mx1
[NCBI] 		3079664 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OR594342 [NCBI]
CDS location
range 42004 -> 42348
strand -
CDS
ATGGGCGACAAAGCCACACCGGAGCAGTGCTACCAGATGACGCTCAAGGACTACCAGCGCTTCGAGCGCATCGTCCTGGACGCCATCAAGGTGCCGCTGAACGTCAATGAGCAAACCGCCCTGACGTTCTTCTGCTACAACGTGGGTCCAGTCTGTACAACCAGCACAGCGTTCAAGCGCTTCAACCAAGGCCGCGCCACTGAGGGCTGCCAAGCCCTGGCCATGTGGAACAAGGTCACGATTAACGGCCAAAAGGTCGTATCCAAGGGCCTCGTGAATCGCCGCAACGCGGAGATCAAGCAATGCCTCGAACCATCGTCGCAATACTCGTCCTTGCTGTGGTAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6DqiX) rather than this protein.
PDB ID
6DqiX
Method AlphaFoldv2
Resolution 94.62
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50