Protein

Protein accession
A0AAT9V7N8 [UniProt]
Representative
8mast
Source
UniProt (cluster: phalp2_17009)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MNFIDVSHYQGTVNMAKVHSAGIKDIGIKVSEGLTIIDPSWQTYYKDAEANGMNTMLYHFGHPSEDPIKQAEFFYNTAKALGLGELPMILDIETNDNNTKIDVDSWSIQFLDHLLSISNHDVGVYSSEWFATTYLPKTLAKYSFHWIAKYSTVAPTLKYAIWQKSQTGHVDGINTPVDIDEGVDSLLADAVTQTEETLFNVVVKDSVYSAFLVNGTTYVLWTALNEYGTPHTYKGNGLMTVNGVDVQGVVYQGDTYLPWTALAENIKPTAVKFLFTV
Physico‐chemical
properties
protein length:277 AA
molecular weight:30845,3 Da
isoelectric point:4,80
hydropathy:-0,10
Representative Protein Details
Accession
8mast
Protein name
8mast
Sequence length
354 AA
Molecular weight
38966,43340 Da
Isoelectric point
5,33971
Sequence
MQAHSSTDIISIDVSNHQYDIDWQKVKAARPDIKVALLKSSEGVSYKDPYYIKNVQGAKSVGILVAPYHFGRPDEDSDAVAEAKFFVSIIKSIGFDLSPVLDVEVGNSSNLSTWIRTFINTIKQETGLNTILYTGNWFIDSRHISGLTDISLWVANYSDVSAPPDSGGWTKWIMWQYTDKVQIPGINGDVDMSYAVSIDALKTGVTPMYQTVKVQINGKPWMDGLFINGSTWVVWTALDAFGTPNTYKGNGLFNINGNDVQGVVYNGSTYLPWRSLAANIQYTQIDGGYNFTIAKPQPAPTPSPTPTQPTTTTTLDKTSAQKVLDMLSKVHDLSDTNSQLVIKYAIDSLTKAIQ
Other Proteins in cluster: phalp2_17009
Total (incl. this protein): 2 Avg length: 315,5 Avg pI: 5,07
Protein ID Length (AA) pI
8mast 354 5,33971
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13500
4R1nt
 5 33,1% 220 1.423E-33
2 phalp2_38365
InEX
 1 28,7% 292 1.757E-26
3 phalp2_36209
7jVrq
 19 31,4% 216 6.051E-22
4 phalp2_8137
6Oav8
 5 31,1% 225 5.828E-17
5 phalp2_34614
5kfc4
 5 26,6% 266 1.397E-16
6 phalp2_13529
7Jyqc
 660 26,2% 232 2.556E-15

Domains

Domains [InterPro]
GH25
Unannotated
Representative sequence (used for alignment): 8mast (354 AA)
Member sequence: A0AAT9V7N8 (277 AA)
1 354 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Alicyclobacillus phage KKP_3916
[NCBI] 		3040651 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OQ846916 [NCBI]
CDS location
range 97131 -> 97964
strand -
CDS
TTGAATTTTATTGACGTATCACACTATCAAGGAACAGTGAATATGGCAAAGGTTCATAGCGCTGGTATAAAAGATATTGGTATCAAGGTATCCGAGGGACTGACCATCATTGATCCGAGTTGGCAGACTTATTATAAGGATGCTGAAGCCAATGGTATGAACACCATGTTGTATCACTTTGGACACCCAAGCGAAGATCCTATCAAACAAGCAGAGTTTTTCTATAACACTGCAAAAGCTCTTGGGCTTGGCGAATTGCCTATGATTTTAGACATTGAGACCAATGACAATAACACAAAGATCGATGTGGATTCATGGTCTATTCAATTCCTCGATCACCTACTCTCCATATCCAATCACGATGTAGGTGTGTATTCGAGTGAATGGTTCGCTACTACCTATTTACCAAAAACACTTGCAAAATATAGTTTCCATTGGATTGCTAAATATTCAACTGTCGCGCCTACCTTAAAGTATGCGATCTGGCAGAAATCGCAGACAGGACATGTAGATGGTATTAATACCCCAGTAGATATAGACGAAGGAGTTGACTCACTTTTGGCAGATGCAGTTACACAAACAGAAGAGACGTTATTTAATGTAGTTGTTAAGGATAGTGTATATTCCGCATTTCTGGTTAACGGGACAACATATGTTCTTTGGACAGCATTAAATGAATACGGAACGCCGCATACATATAAAGGAAACGGTCTTATGACAGTGAATGGCGTGGATGTTCAGGGTGTTGTATATCAAGGCGACACATATCTCCCGTGGACAGCTTTGGCGGAGAATATCAAGCCGACCGCAGTTAAGTTCCTGTTTACAGTATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8mast) rather than this protein.
PDB ID
8mast
Method AlphaFoldv2
Resolution 88.86
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50