Protein

Protein accession
A0AAF0PIL6 [UniProt]
Representative
79q9u
Source
UniProt (cluster: phalp2_10026)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MATKLVSKQCVDFVKSFEGFSATPYIDCVGVKTLGYGMTGKEIAGLTSVTEAQAAQMLEDLMNTQYATPIKSYLDSKGVKLNQNQFDALVSMAYNIGTAGLLGSTLMKNIVAGVRDVATITANFTTWSKGTVNGQLTTIAGLLRRRQAEAKMFFGTGNTITGSTGEVKKKVKCIVIYNVGADQNSAEILADYLQCPTISNSRKFDYSQIETVYAVGGKKEQYTSYLTKLISGADRYKTNQAVLDFIKAGGK
Physico‐chemical
properties
protein length:251 AA
molecular weight:27085,8 Da
isoelectric point:9,19
hydropathy:-0,09
Representative Protein Details
Accession
79q9u
Protein name
79q9u
Sequence length
237 AA
Molecular weight
26224,34400 Da
Isoelectric point
8,97002
Sequence
MGLVSKQCVDFVKRFEGFYPNPYYDIVGVKTLGYGMTGKEIEGLSSVTESQASKMLEDLLNNKYAIPIKQDLDRRGVKLNQNQFDALVSMAYNVGYAGVLGSTLYKNICNGVRDKATITANFEMWSMAGGEQVYGLLRRRREEAAMFFGSSNSSSSETNAGGSYYNVKEVQNMLIKIGYPCGKYGADGSWGNGTKTAVEAFQKDCNLKVDGWVGNDTYHKIVAEYNKKNGNKTKTRS
Other Proteins in cluster: phalp2_10026
Total (incl. this protein): 11 Avg length: 267,5 Avg pI: 9,09
Protein ID Length (AA) pI
79q9u 237 8,97002
10D5F 211 9,38694
1bXfD 312 8,91741
2aWVK 271 9,44612
6WS5N 255 9,37759
7h4uU 312 8,70131
7ou3R 312 8,65361
7rrBo 219 9,29900
8Hj3e 312 8,80195
A0AAF0T2J6 251 9,19069
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_34525
4Suj2
 1 54,8% 239 4.948E-86
2 phalp2_5393
2zLq1
 3 71,9% 157 4.206E-78
3 phalp2_34307
3A2Hz
 178 38,5% 231 2.675E-38
4 phalp2_30967
1cc13
 10 35,6% 233 8.421E-32
5 phalp2_11300
6W5mc
 5 42,7% 145 2.373E-27
6 phalp2_4451
31DIk
 4919 41,1% 153 4.410E-27
7 phalp2_4532
3QBcV
 9 36,5% 145 7.152E-26
8 phalp2_22738
7ZWXa
 59 40,0% 155 1.809E-25
9 phalp2_27796
7vIKE
 3 32,2% 242 1.809E-25
10 phalp2_15045
7iQxx
 18 38,0% 147 1.574E-24

Domains

Domains [InterPro]
GH24
PG_1
Representative sequence (used for alignment): 79q9u (237 AA)
Member sequence: A0AAF0PIL6 (251 AA)
1 237 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959, PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Clostridium phage vB_CtyS-FA70
[NCBI] 		3065431 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OR113390 [NCBI]
CDS location
range 19769 -> 20524
strand +
CDS
ATGGCAACTAAGCTAGTATCAAAACAGTGTGTAGATTTTGTTAAGTCTTTTGAAGGATTTTCAGCTACACCATATATAGACTGTGTTGGGGTTAAGACTCTCGGTTATGGTATGACTGGAAAAGAAATCGCAGGTCTTACATCTGTTACAGAAGCACAGGCTGCTCAGATGTTAGAGGACTTAATGAACACACAGTACGCTACACCTATAAAGAGTTATCTGGACTCAAAGGGTGTTAAACTTAATCAGAACCAATTCGACGCTCTTGTATCTATGGCTTACAACATAGGTACAGCAGGTTTACTTGGCTCTACACTTATGAAGAACATTGTAGCAGGTGTTAGAGACGTAGCGACTATCACAGCTAACTTTACAACGTGGAGCAAGGGAACAGTTAACGGACAGCTCACCACAATAGCAGGTTTGCTGAGACGTAGACAAGCAGAAGCTAAGATGTTTTTTGGTACGGGTAACACTATAACAGGAAGTACAGGGGAGGTAAAAAAGAAAGTGAAATGTATAGTAATTTATAATGTAGGTGCCGACCAAAATAGTGCAGAAATTCTTGCAGATTATTTACAGTGTCCTACAATATCTAACAGCAGAAAATTCGATTACAGTCAGATAGAAACTGTATATGCAGTTGGTGGAAAGAAAGAACAGTACACTTCTTATTTGACAAAATTGATATCAGGTGCAGACAGATATAAGACAAATCAAGCTGTTTTAGACTTCATAAAAGCAGGTGGAAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (79q9u) rather than this protein.
PDB ID
79q9u
Method AlphaFoldv2
Resolution 86.94
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50