Protein

Protein accession
A0AAE9UUB6 [UniProt]
Representative
5TBA5
Source
UniProt (cluster: phalp2_20806)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRFVDISNWKADVDVSKIDADGVVVQCTWGAGELTTDNGLVDSVWVGADAKIQAAAARGLAVGYMHYIRGVNASEEAYFFAEATKGYLGKFVPCVDWESDDNAAWGNRAYLDEFLYQYIRLTGVKPLVYAQRSEIPFIKDICGKHDCGIWEACYASMDAVGWQDADSIWSYVAYPMRQYTSNGHIGGYAGSLDLNYFDGDKAAWDKYAGVGANTPVNPAPVPVVDPSPTVIATSYEVSVDSLNVRTEPSVKGDVVADYVRGQKVVLDGWGAYADGFLWGRYIGASSGEPRYIAIGTDSGSEWYLTMCR
Physico‐chemical
properties
protein length:308 AA
molecular weight:33652,2 Da
isoelectric point:4,50
hydropathy:-0,13
Representative Protein Details
Accession
5TBA5
Protein name
5TBA5
Sequence length
134 AA
Molecular weight
14900,47910 Da
Isoelectric point
4,71612
Sequence
MRFVDISNWKADCDVSKIDADGVVVQCTWGAGELTTDNGLVDSVWVGADAKIQAAAARGLAVGYMHYIRGVNASEEAYFFAEHTKGYLGKYVPCVDWESDDNAAWGNRAYLDEFLYQYIRLTGVKPLVYAQRSE
Other Proteins in cluster: phalp2_20806
Total (incl. this protein): 9 Avg length: 288,7 Avg pI: 4,56
Protein ID Length (AA) pI
5TBA5 134 4,71612
A0A9Y1HR21 308 4,68429
A0AAE9URE6 308 4,68429
A0AAE9UVD1 308 4,49945
A0AAE9V0Q7 308 4,49945
A0AAE9V1T3 308 4,49673
A0AAF0A787 308 4,49945
A0AAF0A7D4 308 4,49945
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_38994
84ePK
 348 41,4% 135 2.522E-24
2 phalp2_40151
8tQ4T
 5 40,0% 135 4.738E-24
3 phalp2_20117
23DDy
 70 33,8% 136 1.948E-12
4 phalp2_39219
3xEyz
 21 34,8% 135 1.142E-10
5 phalp2_3635
4SEzC
 3 27,1% 129 3.549E-09
6 phalp2_9123
5Tx0T
 16 31,5% 92 5.367E-05
7 phalp2_2231
4klcC
 109 30,1% 136 1.353E-04

Domains

Domains [InterPro]
GH25
Representative sequence (used for alignment): 5TBA5 (134 AA)
Member sequence: A0AAE9UUB6 (308 AA)
1 134 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Bifidobacterium phage BP677P8
[NCBI] 		2968619 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP172704 [NCBI]
CDS location
range 21595 -> 22521
strand +
CDS
ATGAGGTTTGTGGATATCAGCAATTGGAAGGCTGACGTTGACGTTTCCAAGATTGACGCCGATGGTGTCGTGGTCCAGTGCACTTGGGGTGCAGGCGAATTAACGACTGACAATGGTCTGGTCGATTCCGTGTGGGTTGGTGCCGATGCGAAGATTCAGGCCGCTGCGGCACGCGGCCTTGCGGTCGGATACATGCACTACATTCGCGGCGTGAACGCTTCCGAGGAGGCGTATTTCTTCGCGGAAGCCACCAAGGGTTATCTTGGCAAGTTCGTGCCGTGCGTGGATTGGGAGAGTGACGATAACGCCGCGTGGGGCAATCGCGCCTACTTGGACGAGTTTCTGTACCAGTATATTCGTCTGACCGGTGTGAAGCCGCTCGTGTATGCGCAGCGTTCTGAAATCCCGTTCATCAAGGATATTTGCGGCAAGCATGATTGCGGCATTTGGGAAGCATGCTATGCGTCCATGGATGCGGTCGGCTGGCAGGATGCTGATTCGATTTGGTCGTATGTGGCGTATCCGATGCGCCAGTACACGTCCAACGGTCATATCGGCGGTTATGCTGGTTCGCTTGACTTGAACTATTTCGACGGCGATAAGGCCGCTTGGGACAAGTATGCCGGCGTTGGTGCGAACACTCCGGTGAATCCGGCTCCGGTGCCGGTGGTTGACCCGTCTCCTACCGTGATTGCCACCTCGTATGAGGTTTCGGTCGATTCGTTGAATGTGCGTACCGAACCGTCCGTTAAGGGCGATGTTGTCGCCGATTACGTGCGCGGCCAGAAGGTTGTGTTGGATGGTTGGGGCGCTTATGCTGACGGTTTCCTGTGGGGCCGTTATATTGGCGCTTCTTCCGGAGAGCCGAGGTATATTGCCATTGGCACTGATTCCGGTAGCGAATGGTATTTGACAATGTGTCGCTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5TBA5) rather than this protein.
PDB ID
5TBA5
Method AlphaFoldv2
Resolution 96.71
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50