Protein

Protein accession
A0AAE9G4V7 [UniProt]
Representative
5CTh0
Source
UniProt (cluster: phalp2_23353)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKTSDKGIAFLVAHEGVVPGPYRDSVGVWTYGVGHTAAAGAPVPEKMKRGMPADLDAALADAFSVFRRDLVKYEADVNRALSVRSVPQHQFDAAVSFHFNTGAIERANWVNIWRNGRVSQAAQNMVANWRTPAEIIERRRAEADLLASGDYGTKKAAVWPVGANGQISWKPVRTLSQQQILAFMSSPALPDVPGAVTKPPAAPVGFFAWLARLFGAW
Physico‐chemical
properties
protein length:217 AA
molecular weight:23539,6 Da
isoelectric point:9,78
hydropathy:-0,11
Representative Protein Details
Accession
5CTh0
Protein name
5CTh0
Sequence length
72 AA
Molecular weight
7766,85420 Da
Isoelectric point
6,82053
Sequence
MHTTDRGLLALVRHEGIVPGPYLDVKQVWTFGIGHTAAAGPPDPSRMPRGMPADLEAGVREAFKVFRTDLAA
Other Proteins in cluster: phalp2_23353
Total (incl. this protein): 10 Avg length: 104,6 Avg pI: 7,26
Protein ID Length (AA) pI
5CTh0 72 6,82053
1ihkx 81 6,24180
1iie2 94 5,70058
300hI 88 6,26089
3GiyQ 129 6,57953
4OTt4 94 6,39219
4xrqg 84 9,68710
iJzb 90 8,27821
kF37 97 6,83025
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1145
7TUH
 5 88,8% 45 4.674E-23
2 phalp2_31138
26ZNc
 11 39,2% 51 5.287E-08
3 phalp2_31530
48EM7
 20 36,6% 71 7.273E-08
4 phalp2_26644
2b0IA
 24 35,4% 62 2.605E-07
5 phalp2_29005
6AlqK
 1 40,0% 45 1.767E-06
6 phalp2_15028
76Khu
 1 35,2% 51 5.538E-04

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 5CTh0 (72 AA)
Member sequence: A0AAE9G4V7 (217 AA)
1 72 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Paracoccus phage vB_PmaP_KLEP18-1
[NCBI] 		2928861 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OM654376 [NCBI]
CDS location
range 31691 -> 32344
strand +
CDS
ATGAAAACGTCGGATAAGGGCATCGCGTTTCTGGTGGCGCATGAGGGCGTCGTGCCGGGGCCGTATCGGGATAGCGTGGGCGTGTGGACGTATGGCGTCGGACACACCGCCGCAGCTGGCGCGCCCGTGCCTGAGAAGATGAAACGCGGTATGCCCGCCGATCTGGACGCCGCGCTGGCCGATGCGTTTTCGGTGTTCCGGCGGGATCTGGTGAAATATGAGGCCGACGTGAACCGGGCGCTGTCGGTGCGATCTGTCCCGCAGCACCAGTTTGACGCGGCGGTGTCGTTCCACTTCAACACCGGGGCGATCGAGCGCGCGAACTGGGTGAATATCTGGCGGAACGGGCGCGTTTCGCAGGCGGCTCAGAATATGGTCGCGAACTGGCGCACGCCTGCGGAGATCATCGAGCGGCGCCGCGCTGAGGCTGACTTGCTGGCGTCAGGTGATTACGGCACGAAGAAAGCCGCTGTATGGCCTGTTGGCGCGAACGGGCAGATCAGCTGGAAACCGGTTCGCACGCTGTCGCAGCAGCAAATCCTGGCGTTCATGTCGTCGCCCGCGTTGCCCGATGTTCCGGGTGCTGTGACGAAACCGCCTGCCGCGCCAGTTGGTTTTTTCGCGTGGCTGGCGCGGTTGTTCGGCGCGTGGTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5CTh0) rather than this protein.
PDB ID
5CTh0
Method AlphaFoldv2
Resolution 95.08
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50