Protein

Protein accession
A0AAE8X879 [UniProt]
Representative
1kJlV
Source
UniProt (cluster: phalp2_39916)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTLRIVDLSSHNNTDLAAYPADGYIVKVTEGTGYVNPLAAGHVTQAKQRGALLGLYMFLLAGVSGAEQAKYFLNQSIVAQNIGTAPLFIDFEDTNYSNITNAAGVSTALDAIRYIKKETGTTPLIYMSRSVENSLDWSSVVAENVGLWVAEYGKPLQALKHWSDVALWQFSSTPYDQSYFYGTAATWAAYAKATKKPDPTPAPAPTPQPGAKQYTDAQGIVWYPETGKVTLNTAVNLRWGAYPTSTLIATLPAGSAVTYDYKAHIGNRIVVRQPRSGGYGYLTVGTANAQGVNVDPYGTFS
Physico‐chemical
properties
protein length:301 AA
molecular weight:32415,0 Da
isoelectric point:6,90
hydropathy:-0,14
Representative Protein Details
Accession
1kJlV
Protein name
1kJlV
Sequence length
409 AA
Molecular weight
45974,38560 Da
Isoelectric point
8,65503
Sequence
MTTTHSGAIDQIWGNYQYLTDIANAAIAKFPGLRITSGFRLGDPHHHGRRMAIDIAFPASRNGDLKYKEVGDWIFDTFPDRVAYVIALDKVRDRNGYSGTGTSGKWVPFPGGGHMDHIHVSGEWGAENIKGGTNMPLNIVDLSNNNGSKNLKDYPADGYVFKATEGNYFVDKFCDQFVQQAIKANKLFGVYHFMDGSNWQQQADFFLKNITGYIGKGLLVLDYEMYGRQGTAIAKKWLDYVYEKTGVKPLVYTSVSVTKEENWSEVVKAGYGLWVADYTPPLDKIGYWPSVAMWQYTEKPYDKNYFYGDKKAWEAYAKSAKKVAETKPTPPKDEQEKIKLRTITINSDGVNLRSAPKVDKNNIIAKLSKGNTIEINDIELASGIIWGVQPRADGTKGYIDLGQQYSWIK
Other Proteins in cluster: phalp2_39916
Total (incl. this protein): 4 Avg length: 364,0 Avg pI: 8,46
Protein ID Length (AA) pI
1kJlV 409 8,65503
5GG30 433 8,90084
A0AAD1KSU7 313 9,39100
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24702
6aXOr
 10 57,2% 248 1.974E-76
2 phalp2_38172
72d4D
 103 30,6% 300 8.081E-39
3 phalp2_8627
24FYC
 3 29,0% 310 6.400E-25
4 phalp2_24235
2VKgf
 225 20,5% 268 7.197E-14
5 phalp2_8715
8a2ww
 4 25,2% 281 2.242E-13
6 phalp2_17635
6JmE3
 482 23,2% 301 3.817E-12
7 phalp2_29128
7804q
 3 22,5% 271 6.150E-10
8 phalp2_39129
2CcXt
 6 23,6% 343 5.845E-09

Domains

Domains [InterPro]
Unannotated
GH25
Unannotated
Representative sequence (used for alignment): 1kJlV (409 AA)
Member sequence: A0AAE8X879 (301 AA)
1 409 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Lacticaseibacillus phage Lphi2ADMT26
[NCBI] 		2866803 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MZ672003 [NCBI]
CDS location
range 1486 -> 2391
strand -
CDS
ATGACATTAAGAATTGTAGACCTATCCAGCCACAACAACACTGATCTCGCCGCCTATCCGGCTGATGGCTATATTGTAAAAGTAACCGAGGGCACCGGGTACGTTAACCCGTTAGCCGCGGGACACGTGACACAGGCTAAACAACGTGGTGCGTTGCTCGGCTTATACATGTTCTTATTAGCTGGCGTGTCAGGCGCCGAACAAGCAAAATATTTTCTTAATCAGTCCATTGTTGCTCAAAACATCGGAACAGCGCCGCTTTTCATCGATTTTGAAGATACTAACTACTCAAATATCACCAACGCAGCCGGTGTGTCAACTGCATTGGATGCCATACGCTATATCAAAAAAGAGACCGGAACAACACCACTCATTTACATGAGTCGATCGGTAGAGAATAGCTTAGACTGGTCAAGCGTAGTCGCTGAAAATGTTGGCTTGTGGGTTGCAGAATATGGCAAACCACTACAAGCACTGAAACATTGGTCGGATGTTGCTTTATGGCAGTTCAGCAGCACGCCCTATGATCAAAGTTATTTCTACGGCACAGCCGCCACATGGGCTGCCTACGCTAAGGCAACTAAGAAACCCGATCCAACACCCGCGCCAGCACCAACTCCGCAACCCGGCGCTAAACAGTACACGGATGCGCAAGGCATTGTTTGGTACCCTGAAACTGGCAAGGTAACGCTTAATACCGCCGTCAATCTAAGATGGGGCGCTTATCCAACATCAACTCTGATCGCAACACTACCAGCTGGTAGTGCCGTGACATACGACTATAAAGCGCACATCGGCAATCGCATTGTTGTCAGACAACCACGATCCGGTGGTTATGGTTATTTGACCGTAGGAACAGCCAACGCGCAAGGTGTCAATGTTGATCCATACGGAACGTTTAGCTAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1kJlV) rather than this protein.
PDB ID
1kJlV
Method AlphaFoldv2
Resolution 87.64
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50