Protein

Protein accession
A0AAE8BUF8 [UniProt]
Representative
7dGsY
Source
UniProt (cluster: phalp2_22243)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MSQIAKMLRVDEGFKSVPYRDTEGYPTIGIGQRIGPKNALMTNYTLTISQPVADLWMQDIALDYMNKIQSDSRISAALTKCNDARRDALLDMAYQLGVSGLSGFRNTLVLISNGDFAKASAEMLNSLWARQTPQRAKRLSETIRLGDYSAYEKMW
Physico‐chemical
properties
protein length:155 AA
molecular weight:17393,7 Da
isoelectric point:9,04
hydropathy:-0,32
Representative Protein Details
Accession
7dGsY
Protein name
7dGsY
Sequence length
98 AA
Molecular weight
11173,05950 Da
Isoelectric point
6,80911
Sequence
MSQIVALLKFEEDYRDMPFIDTQGHPTVGCGIKIDPKGASLAIYIFKVPGVVGDLWMQALVMSKIYDMKQKLQLAEVLNKCNLPRADILYSMAYHHWN
Other Proteins in cluster: phalp2_22243
Total (incl. this protein): 6 Avg length: 146,7 Avg pI: 8,49
Protein ID Length (AA) pI
7dGsY 98 6,80911
A0A513ZZU2 158 9,01824
A0A514A0W5 158 8,79866
A0A514A0L5 158 8,79866
A0A5B9N689 153 8,47445
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_15021
74f9k
 98 40,0% 95 1.000E-24
2 phalp2_19784
7S0Q8
 16 50,7% 69 2.586E-24
3 phalp2_40539
4IUJh
 1 18,8% 90 8.267E-08
4 phalp2_1386
1iVBH
 20 21,8% 96 5.034E-06
5 phalp2_10217
QCLp
 3 22,8% 83 6.903E-06
6 phalp2_37314
8cGw2
 1 26,0% 96 2.441E-05
7 phalp2_31547
4dEqB
 6 23,0% 113 1.620E-04
8 phalp2_2016
2hQSl
 5 22,4% 98 1.620E-04
9 phalp2_9019
535M3
 35 19,3% 88 7.826E-04

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 7dGsY (98 AA)
Member sequence: A0AAE8BUF8 (155 AA)
1 98 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Erwinia phage AH03
[NCBI] 		2869568 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MZ501266 [NCBI]
CDS location
range 8743 -> 9210
strand +
CDS
ATGTCGCAAATCGCGAAAATGCTAAGGGTTGATGAAGGCTTTAAATCTGTGCCTTACCGGGATACAGAGGGCTATCCTACTATCGGAATCGGTCAGCGAATCGGTCCGAAAAACGCACTGATGACTAATTACACCCTTACGATTAGTCAACCGGTTGCTGATTTATGGATGCAGGACATTGCACTGGATTACATGAATAAGATTCAATCCGATTCGCGAATCTCTGCGGCATTAACTAAGTGCAATGATGCACGGCGCGACGCGCTGCTTGATATGGCCTATCAGCTTGGCGTTAGCGGTCTGTCCGGCTTCCGTAATACGCTGGTGCTGATTTCTAACGGTGACTTCGCCAAAGCTTCAGCGGAAATGCTCAATTCATTGTGGGCAAGACAAACTCCGCAGCGTGCCAAACGTTTAAGTGAAACTATTCGTTTGGGTGATTATTCGGCTTACGAAAAGATGTGGTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7dGsY) rather than this protein.
PDB ID
7dGsY
Method AlphaFoldv2
Resolution 92.60
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50