Protein

Protein accession
A0AA96J1P5 [UniProt]
Representative
27aI4
Source
UniProt (cluster: phalp2_1531)
Protein name
Lysozyme
Lysin probability
99%
PhaLP type
VAL
Probability: 95% (predicted by ML model)
Protein sequence
MDSVKSLNQFFTKLGKEFQQVSENSKRNETLLTKLFKSETKEEKDRKKAQGRVTTRKKRATQKKKRSKLDTIKALKSVFNKLLGKDEEKKGPGLLKTILGGGAIVALLGAAAWKKFEDEVKKTVGSVKDNITGGINDFIRRITGQIDEEVKGVEDEVTGGLSEVEGEAAAANSRVTKPEAEPQGQQTQQPAQTNQEVVAEERELQDSGVTRPAETVVEETKTTEAKNTSTARRTRTTDTATKETRVEETRVLETDDTTNRETTRSTKETERELKETTSTPSSATRRSRYRNRRSGVENVTGKKTTEPTKPKPKTPAQSAAEAMKKAGPASSAPAVSAGKMTSTQKKALGVLAKYESGAAGYDAVNQIGTKGGRGVAGFSGDIKRMPQHKGRSLTDFTIKEIKALQYDDRTLSNSQWIKKGKLHAVGRYQFIGNTLPGVAKRAGVSDNDKFTPEIQDRMALQLMKERGISPWVGPSDKATSAERAIIRQARQQELPTRRQKGGAVGIATDHIKKDEALSSLTKGSNDWIREGGTSVVSSTPWSKVSPDTQIHAYKDSVGVSTIGWGSTYYDNISSGSKKVQMGDTITKKRADDILSTNVSMLSRKLSKDVGSNWSKMSDKQQASLLSMGYNAPNFLSSPTFAPKLRGAIQSGDMETAADNLEWGGPSATRISESQKMLRSGPMDLTKVETPKVSTETKTSAAKVMKQSGQKQKKKEEKKPWWRFGFQQGGFVPYAKDSTSSDTFTESGELNLNKIIDRPNFDSAPKSAPNSAPFQQTNGSVVPAGGFQQSMGSVVSTAPFMQSMGSVGPVDGFQQSMGSVVPTAPFTQSMGSVVPTAPFTQSMGSVAPAGGFQQSMGSVAPAGGFQQSMGSVAPAGGFQQSMGSVGPVDSFQQTNGFSGVSEGFLQSMGYLAPTANFQQSDGSVAPADNFQQTNGSVSRGPSFIQRIASMLSFGRADQTNGSVAPVDNFQQTNGSVASSPSFAQSMGTPSVLRGPQQSSGAASVAPAPVTAESLGLPSIQEIEKMTIQKLNTYLDPAKTGASEPRVFEAARAAKEKARQEGVKEEMEIQRLGQVAAVKAKMEVKIETARAAAQKKSVEQFRQTNGSAGKSPSFAQSMSIAKLYSGAEQTNGSVASVVPFAQTNGSVGPAGMFQQTNGSVAKSPSFSQSMGLASSTTPFAQTNGSVGPVDSFQQSMGSVAPTGGFQQSMGSVAPAGMFQQSNGSVAPTGGFQQSNGSVKRSSFFQQALGAVAPVAKFSQSMGRIGSRRGGVRQKMRGYARAGSNFVQSMGQVGESPRFSQAMGTVGNLLGSAQNAMRYQQGGSVSGSTIMGEAPKEGGIVPGSGTGDQYPISLPEGSFVLNKKATETLHRLQQGGVASISSNSMSKIEQRFFNANEVYSETMKKKKKRPVVVVDIPAPSSPGVSASPTPQSLETGGNGGLNMNTIRSKMHRVNAGSLF
Physico‐chemical
properties
protein length:1456 AA
molecular weight:154645,6 Da
isoelectric point:9,83
hydropathy:-0,60
Representative Protein Details
Accession
27aI4
Protein name
27aI4
Sequence length
870 AA
Molecular weight
94200,71870 Da
Isoelectric point
9,33078
Sequence
MPISKSERLRKAYESKLGKNLVSKLSDDQIKLISKYYNSLSDSEQSNIDSAIVQGKTNTDLHEMARGFIEEEEDSEQMPEGLDDLLNSIRAPKAKVTKITSSALVAVGGSGKKVDGKKFFGESKYQKYIDELTSSGTIDGEQLSPAERKEGFKKRGDKIAFEDFVKKILDRKESQFISQEKKKLSGAQIKSPLAIATPKVDDKKVIQKPEPEQVVSPASEETQENLDDILDKIDSILDTIKNEEKAKKKKDKEDSREREKKRRKKKEEKLESSIFKGLAKGVDKVLQPVKSIFKKIFDFFTAIFFARIVTKIFDWLGDRENQQKLKSLIRFLSDFWPVIAGAYLLFGTKFGKLIRTIGKWAVQIAKFAIPKLLRFISKNPRTAILLAGAGYLGARILTNKEAGGEDEDTSGEETSQSQTDQGESKQSDGTTPEPMEFSKGGSVPGSGNRDTIPAMLTPGEFVMSKGAVAKYGTNTLASMNSVGGGTNIPSFSDGLMGFQGGGSVPGGDEAKTKEQRGPMSWMGNLFGGGSKPPATPAAAKPKSGGLTDIQKRALAVLAKYESGAAGYNAVNQIGTSGGRGVKGFSGDIRKMSQHKGRSLTDFTIGEIKALQRENKSMSDSQWIKAGKLHAVGRYQFIGNTLPGVAKRAGIPDNAKFTAGVQDLMALQLMKERGISPWVGPSDKATNAERAIIAQARKQPIKFDPSMPTGSSVGADVDIASSSGSDADISSDGGVEEQKLVYDAASDSYIIQGGESSGQKVKTFDWAAMRTALGVSNEASDEKTKRIFESEYSSAPKLESVQSLNSKVESVSKSSKPSTLISPGQSQQMSYGGSSPGGPINPSQRVRTDIPYFDSMAMISPRKIKTLGIMI
Other Proteins in cluster: phalp2_1531
Total (incl. this protein): 67 Avg length: 756,5 Avg pI: 9,46
Protein ID Length (AA) pI
27aI4 870 9,33078
146dl 746 9,62901
16pxz 724 9,59620
16rH1 676 9,86233
1BeNl 776 9,54856
1Bj8a 711 9,55210
1MXDP 751 9,58144
1SSFK 725 8,39251
1TX5Q 733 9,09573
1TeLN 850 9,32808
1UK0K 814 9,52664
1fGwU 692 9,34245
1s0OV 779 9,25432
1sASi 722 9,61328
1sLuk 724 9,58969
1sXYE 723 9,61328
1sdlx 724 9,60658
1tBRr 722 9,62012
1tnic 723 9,60000
1uCzj 719 9,63656
1v4z0 719 9,62972
1vY7B 723 9,60000
1vf0Y 722 9,58962
1w8St 714 9,45437
1wCvY 714 9,43213
1xqRC 719 9,63656
228tb 782 9,60942
22aq0 744 9,12036
24fSl 713 9,58292
28Z2U 893 9,17761
2KIiL 536 9,92724
2KjV5 728 9,58595
2vYf5 811 9,08019
2zOYJ 760 8,97492
3C0gY 744 9,63868
3Ev0c 699 9,29172
3oK2W 746 8,94481
3oP6T 708 9,15337
4OSb4 806 9,24072
4R9Lx 850 9,67640
4XfW0 859 8,76656
4Xg0u 746 9,57119
4jvcW 714 9,08883
4x2ev 721 9,66763
4x3Kj 732 9,63798
4xGt7 733 9,24936
5dSqJ 692 9,59291
5hqN 552 9,57860
5yCg4 737 9,21442
7zY4v 766 9,56590
8BBB0 678 9,63688
8BKyG 721 9,58292
8DyLb 979 9,39661
8FIPD 734 9,63798
8GaOC 850 9,35522
8gOFb 837 8,92637
8gRq5 723 9,73242
8h6GG 721 9,58292
8hWh2 850 9,67640
8q6tf 852 9,67640
8vwoH 775 9,31099
8zIYB 723 9,73242
Afiq 677 9,80978
dQ9q 721 9,67234
qQIo 850 9,35038
tno2 550 9,25484
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3839
6BqfU
 33 33,0% 762 1.352E-136
2 phalp2_26873
4dtvZ
 1 31,0% 701 1.447E-83

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Synechococcus phage S-CREM2
[NCBI] 		3075959 Kyanoviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OR473000 [NCBI]
CDS location
range 159184 -> 163554
strand +
CDS
ATGGATAGCGTAAAATCACTCAACCAGTTCTTTACCAAGTTAGGTAAGGAGTTCCAGCAGGTATCTGAGAACTCCAAGAGGAACGAAACTCTGCTTACTAAACTCTTCAAGTCCGAAACAAAGGAAGAGAAGGATAGGAAGAAAGCGCAAGGAAGAGTAACTACCCGTAAGAAGAGGGCAACGCAGAAGAAGAAGCGCAGTAAGCTTGATACCATCAAGGCACTGAAGAGTGTCTTCAATAAGTTGTTGGGTAAGGACGAAGAGAAGAAAGGTCCTGGACTGTTAAAGACTATACTTGGTGGTGGTGCTATCGTCGCACTGCTGGGTGCTGCCGCATGGAAGAAGTTTGAGGACGAAGTCAAGAAGACTGTTGGTAGTGTAAAGGATAACATTACTGGTGGTATTAACGACTTCATAAGGAGGATAACAGGGCAGATTGATGAAGAGGTAAAGGGTGTTGAGGATGAAGTTACTGGTGGTTTATCTGAAGTAGAGGGAGAAGCTGCTGCCGCTAACTCCAGGGTAACTAAACCTGAAGCAGAACCCCAAGGTCAGCAGACACAACAACCCGCACAAACCAACCAAGAAGTTGTTGCTGAAGAGAGGGAACTTCAGGACAGTGGAGTAACTCGCCCCGCCGAGACAGTAGTAGAAGAAACAAAAACAACAGAGGCAAAGAACACTTCTACTGCCCGCCGCACAAGAACTACTGATACTGCAACAAAGGAGACACGAGTTGAGGAGACCCGTGTTCTAGAAACAGATGACACGACAAACAGAGAGACTACTCGTTCTACAAAAGAAACAGAGAGAGAACTAAAGGAAACAACATCCACTCCTTCTTCTGCGACGCGACGCAGTCGTTATCGTAATAGGCGTTCGGGTGTTGAGAACGTAACTGGGAAGAAGACCACAGAACCCACCAAACCTAAGCCAAAGACTCCGGCACAGTCTGCAGCCGAGGCTATGAAGAAGGCAGGTCCTGCTTCTTCTGCCCCTGCGGTTTCTGCTGGCAAGATGACCAGCACTCAAAAGAAAGCACTTGGTGTTCTTGCGAAGTATGAGTCTGGTGCTGCTGGTTATGACGCAGTCAATCAGATTGGAACAAAAGGTGGTAGGGGTGTCGCTGGTTTCTCTGGTGACATCAAGAGAATGCCTCAACACAAAGGCAGGTCTCTGACTGACTTTACTATTAAAGAGATCAAAGCACTTCAGTATGATGATAGGACTCTATCCAATAGCCAGTGGATCAAGAAAGGCAAACTTCACGCCGTAGGTCGTTATCAGTTTATTGGTAACACCCTCCCTGGTGTTGCGAAGCGTGCTGGTGTCTCCGACAACGACAAGTTTACTCCTGAAATTCAGGACCGCATGGCCCTTCAACTTATGAAGGAGCGTGGCATTAGTCCTTGGGTTGGTCCTAGCGACAAGGCAACTTCTGCCGAGAGAGCAATCATTAGGCAGGCAAGACAGCAAGAGTTGCCTACTAGGAGACAGAAAGGTGGCGCTGTTGGCATCGCAACCGACCACATCAAGAAAGACGAAGCGCTATCTTCACTCACCAAAGGTTCTAACGACTGGATCCGCGAGGGTGGAACTTCTGTTGTAAGTAGCACACCCTGGTCTAAGGTAAGTCCAGACACACAAATTCATGCCTACAAGGATAGTGTTGGTGTTTCTACTATTGGTTGGGGTTCTACTTACTATGACAACATCTCTTCTGGAAGTAAGAAGGTCCAGATGGGTGATACTATCACCAAGAAGAGGGCGGACGACATCCTGAGCACCAACGTCAGCATGCTTAGCAGAAAACTTTCTAAGGATGTTGGTTCTAACTGGTCTAAGATGTCAGACAAGCAGCAGGCATCTCTGCTGTCTATGGGTTATAACGCTCCTAACTTCCTGAGTTCCCCCACCTTTGCACCCAAACTCCGTGGTGCTATTCAGAGTGGTGACATGGAAACCGCTGCTGATAACTTGGAGTGGGGTGGTCCTTCTGCTACTCGCATCTCTGAGTCTCAGAAGATGCTTCGTAGTGGTCCTATGGATCTCACTAAGGTTGAGACGCCTAAGGTTTCTACTGAAACTAAGACTAGTGCTGCTAAGGTTATGAAGCAGTCAGGTCAGAAACAGAAGAAGAAAGAAGAGAAGAAACCTTGGTGGCGTTTTGGTTTCCAGCAAGGTGGTTTTGTTCCTTACGCAAAGGACTCTACTTCCTCCGACACTTTCACTGAGTCTGGTGAGTTGAACCTCAACAAGATCATTGATAGACCTAACTTTGACTCTGCCCCTAAGTCTGCCCCCAACTCTGCCCCCTTCCAGCAGACTAACGGTTCAGTTGTCCCTGCTGGTGGTTTCCAGCAGTCTATGGGTTCTGTTGTTTCTACTGCACCTTTCATGCAGTCTATGGGTTCTGTTGGTCCTGTTGACGGTTTCCAACAGTCTATGGGTTCTGTTGTCCCTACTGCACCCTTCACGCAGTCTATGGGTTCTGTTGTCCCTACTGCACCCTTCACGCAGTCTATGGGTTCTGTTGCCCCAGCAGGTGGTTTCCAGCAGTCTATGGGTTCTGTTGCCCCAGCAGGTGGTTTCCAGCAGTCTATGGGTTCTGTTGCCCCAGCAGGTGGTTTCCAGCAGTCTATGGGTTCTGTTGGTCCTGTTGATAGTTTCCAGCAGACTAACGGTTTCAGTGGTGTGAGTGAGGGTTTCTTGCAGTCTATGGGTTACCTTGCCCCTACTGCTAACTTCCAACAGTCTGATGGTTCTGTTGCTCCTGCTGATAACTTCCAGCAGACTAACGGTTCTGTTTCTAGGGGTCCTTCCTTTATTCAGAGGATCGCTTCTATGCTTTCCTTTGGTCGTGCTGACCAAACCAACGGTTCTGTCGCACCGGTTGATAACTTCCAGCAGACTAACGGTTCCGTTGCTTCGTCACCTTCCTTTGCTCAGTCTATGGGGACACCTTCTGTTCTGAGAGGACCCCAACAGTCTTCGGGTGCTGCTTCTGTTGCTCCTGCTCCTGTGACTGCGGAGTCTCTTGGTCTTCCTTCCATCCAAGAGATTGAGAAGATGACTATTCAGAAACTCAACACTTACCTTGACCCCGCCAAGACCGGTGCTTCTGAACCTCGTGTCTTTGAGGCGGCAAGAGCAGCGAAAGAGAAGGCAAGACAGGAAGGCGTCAAGGAAGAGATGGAGATCCAGCGTCTCGGACAGGTTGCTGCGGTTAAGGCAAAGATGGAAGTAAAGATTGAGACAGCACGCGCTGCTGCACAGAAGAAGAGTGTGGAACAGTTCAGACAGACTAACGGTTCTGCTGGTAAGTCTCCTTCTTTTGCTCAGTCGATGAGTATTGCTAAACTCTATTCTGGTGCAGAGCAAACTAACGGTTCTGTTGCAAGTGTGGTGCCTTTCGCACAGACTAACGGTTCTGTTGGTCCTGCTGGAATGTTCCAACAGACTAACGGGTCGGTTGCTAAGTCTCCTTCCTTTTCTCAGTCTATGGGTCTTGCTTCCTCCACCACACCTTTCGCACAGACTAACGGTTCTGTTGGTCCTGTTGATAGTTTCCAACAGTCTATGGGTTCTGTTGCTCCTACTGGTGGTTTCCAACAGTCTATGGGTTCTGTTGCTCCTGCTGGCATGTTCCAACAGTCCAACGGTTCTGTTGCTCCTACTGGTGGTTTCCAACAGTCCAACGGTTCTGTTAAGAGATCTAGTTTCTTCCAGCAAGCACTAGGTGCTGTTGCTCCTGTTGCTAAGTTCTCTCAGTCTATGGGACGCATTGGATCTAGACGAGGTGGTGTTAGACAGAAGATGAGAGGTTATGCTCGCGCTGGTTCTAACTTTGTTCAGTCTATGGGTCAAGTTGGTGAGAGTCCTAGGTTCAGTCAGGCGATGGGAACTGTTGGTAACCTTCTTGGCTCTGCTCAGAACGCTATGAGATACCAGCAGGGTGGTTCCGTTTCTGGTTCTACTATTATGGGTGAGGCACCTAAGGAAGGTGGCATTGTTCCTGGTTCTGGAACTGGTGACCAATACCCTATCTCTCTACCTGAGGGTTCCTTTGTTCTCAACAAGAAGGCAACTGAAACTTTGCATAGACTTCAACAGGGTGGTGTTGCTTCTATCAGTAGTAACAGCATGAGTAAGATTGAGCAGAGGTTCTTCAACGCCAACGAGGTTTACTCTGAGACTATGAAGAAAAAGAAGAAGCGTCCGGTTGTTGTTGTTGACATCCCTGCCCCTTCTTCGCCAGGTGTTTCTGCCTCACCGACCCCACAGTCACTAGAAACTGGTGGCAATGGTGGTCTAAATATGAATACGATCCGTAGTAAAATGCATAGGGTCAACGCTGGCTCGCTCTTCTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (27aI4) rather than this protein.
PDB ID
27aI4
Method AlphaFoldv2
Resolution 62.48
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50