Protein

Protein accession
A0A9X9K6G5 [UniProt]
Representative
72wcG
Source
UniProt (cluster: phalp2_354)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MGYIVDLSHHQDPKRIDYDTFAKHLDWAVIRTQYGSNTIDRHYKTHHAELRKRGVPTAAYAWVRGVSIADMQKEAEDFYKRTLEAVEPTFWFLDVEEKSMDDMRAGVSAYVAKLRELGAKKIGIYVAHHLYKLFNLNLDEVNAVWIPRYGANSGKPDKKPEFPCDIWQYTSVGRVPGYVGDLDLNMLIGDKDLAWFTGAKVEAKPKPKPEPKPAPKPSFTTYTVRKGDTLWEISQKYKTTVNELVRINKIKNPDLIYPGQKLKVPGKAPSKPKVTGKYYTVKKGDTLWEIAKKYNTTVAKLVSLNKIKNPDLIYPGQKIRIK
Physico‐chemical
properties
protein length:322 AA
molecular weight:36842,1 Da
isoelectric point:9,57
hydropathy:-0,60
Representative Protein Details
Accession
72wcG
Protein name
72wcG
Sequence length
340 AA
Molecular weight
38394,18530 Da
Isoelectric point
9,45011
Sequence
MDNIVDLSHHQKPCEIDYDKFAKCLDLAIIRTQYGSQVVDEHYKTHHNELRKRGVPTHAYAWVRGVSISDMEKEATDFYNRTKEFNPEVWWLDVEEKSMKDMRAGVSAYQRKLRELGAKKVGLYIAHHLYEDFNINISEFDAVWIPRYGDNNGKFHAIKPAFPCDLWQYTSTGRLPGYNGDLDLNKLTGSKSLEWFVGKNISTKPIPSKPANTSSPKPVVKDEKYKVNRIINGYVSAADAKSKKNAKGTVAPGSYFVFNKSEGMINVTDKKGVPGSWINSADNKKAVPKPKDTKKYVTVKSGDTVSGLAKANGSTVAEIKNWNNLKDVNKIYVGQRLRVK
Other Proteins in cluster: phalp2_354
Total (incl. this protein): 31 Avg length: 333,6 Avg pI: 8,00
Protein ID Length (AA) pI
72wcG 340 9,45011
11BTR 377 9,41981
1D3wB 315 9,42774
1HKnk 389 9,66718
1QQgV 383 9,84692
2G2cj 312 9,01811
2G58y 320 9,56467
2G8qB 324 9,55733
2G8r6 320 9,60735
3mXOt 326 9,67272
4EqLH 354 6,24890
4MK3O 364 5,47043
4N0gE 326 5,54876
4TvGs 344 5,80783
5nN9q 342 5,77714
63ukV 286 9,56448
75ej6 331 6,27255
7rP8s 286 9,33962
7sIHu 335 6,55401
7sIVh 331 6,20457
7szJZ 295 6,04417
7vADk 307 9,80772
7yZRg 366 9,57151
8maWs 329 4,94735
8mbqk 341 4,90943
8mbrC 335 4,84680
buM2 316 9,63340
gXTU 300 6,73573
ugZh 372 9,91583
uhcy 353 9,87161
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32227
7cHL2
 31 42,1% 235 5.333E-85
2 phalp2_9283
7cTgF
 101 28,6% 349 1.409E-50
3 phalp2_36983
8LseV
 77 24,4% 417 3.859E-46
4 phalp2_26548
858CP
 728 28,4% 358 2.224E-40
5 phalp2_29128
7804q
 3 28,1% 224 2.237E-38
6 phalp2_22096
5ZSom
 2292 24,3% 361 1.207E-36
7 phalp2_17042
7nSW4
 41 23,2% 352 2.436E-31
8 phalp2_13693
6fI1M
 1 26,1% 360 9.332E-30
9 phalp2_39679
5kP
 52 23,1% 354 3.139E-29
10 phalp2_1416
1rulh
 1 38,2% 222 1.326E-26

Domains

Domains [InterPro]
GH25
Unannotated
LysM
Representative sequence (used for alignment): 72wcG (340 AA)
Member sequence: A0A9X9K6G5 (322 AA)
1 340 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01476

Taxonomy

  Name Taxonomy ID Lineage
Phage Geobacillus phage vB_GthS_PK5.2
[NCBI] 		2985567 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP341629 [NCBI]
CDS location
range 18152 -> 19120
strand +
CDS
ATGGGCTATATCGTCGATCTCTCTCATCACCAAGACCCGAAACGGATTGACTACGATACTTTCGCAAAACATCTCGATTGGGCGGTGATCCGAACACAGTACGGGTCAAATACGATTGACCGACACTATAAAACTCATCACGCAGAACTCCGCAAACGTGGCGTACCTACTGCGGCATATGCTTGGGTTCGCGGCGTATCGATTGCGGACATGCAGAAAGAGGCCGAGGACTTCTATAAGCGGACGCTTGAAGCCGTTGAGCCAACCTTCTGGTTTCTCGACGTCGAAGAAAAGTCGATGGACGACATGCGCGCCGGTGTGTCGGCATATGTCGCAAAACTGCGCGAACTTGGCGCGAAGAAAATCGGGATTTACGTAGCACACCATCTCTATAAATTGTTCAATCTTAACCTTGATGAAGTGAATGCGGTATGGATTCCGCGGTATGGCGCCAACAGCGGCAAGCCAGACAAAAAACCGGAATTCCCGTGCGACATTTGGCAATATACGAGCGTCGGTAGAGTCCCCGGTTACGTAGGCGATCTTGATCTGAACATGCTGATCGGAGACAAAGACCTAGCTTGGTTCACGGGGGCAAAAGTCGAAGCCAAGCCGAAACCAAAGCCGGAGCCGAAACCGGCGCCAAAACCATCCTTCACCACATACACGGTCCGAAAAGGAGACACGCTTTGGGAAATCTCGCAAAAATATAAAACGACTGTAAACGAGTTAGTCCGGATCAACAAAATCAAAAACCCAGACCTCATCTATCCTGGCCAAAAATTGAAAGTGCCTGGTAAAGCGCCTAGCAAACCAAAAGTGACCGGAAAGTACTACACGGTCAAAAAAGGGGACACGCTTTGGGAGATTGCGAAAAAATACAATACGACCGTGGCTAAATTGGTAAGTCTCAACAAAATCAAAAACCCGGACTTGATTTATCCGGGGCAGAAAATTCGGATTAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (72wcG) rather than this protein.
PDB ID
72wcG
Method AlphaFoldv2
Resolution 89.62
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50