Protein

Protein accession
A0A9E7SGB2 [UniProt]
Representative
7qyOK
Source
UniProt (cluster: phalp2_29156)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVNIIQDFIPKGNKNRPAYPMNPLYITVHNTSNTAKGADAASHARYVKNPETATSWHFTVDDEKIYQHLPLNENGWHAGDGNGTGNRKSIGIEICENSDGDFEKAVSNAQWLIKKLMKEQGISFANVVPHKHWSGKECPRKLLDRWDSFKAGINGAASSPTKTVKKTTGDTYTVKKGDTLSEIAKEHGGSVANLQSWNNIKDPNKITVGQKLKLKGSSPKPSSKKTSYALPSGIFKVTNPMRKGDDVRRIQKALAALYFYPDKGAKNNGIDGVYGPKTANAIKRFQSIYGLVADGIYGPKTKSKLKALL
Physico‐chemical
properties
protein length:309 AA
molecular weight:33886,1 Da
isoelectric point:9,76
hydropathy:-0,68
Representative Protein Details
Accession
7qyOK
Protein name
7qyOK
Sequence length
359 AA
Molecular weight
39326,18900 Da
Isoelectric point
9,63366
Sequence
MPEIIKDFLPRSLKNQRPGNPMTPKYITVHNTANSSKGADAEMHSRYLHNGAGGRVVGWHLTVDDKEIYQHLPTDENGWHAGDGNGDGNMSSIGIEICENSDGDFDKAVKNAQWLVKKLMKEHNISINNVVPHKHWSGKNCPRLMLGNWDEFIEGIKGASGTVDAPSQQVGSETVTNGSVVDYLNSIDKDASFSNRAKLAKQYGIKGYKGTADQNLELLNKLKKGKPLSKPSKSIKVGSKVYLSKGAKKYATGENIPSSIKGKTYTVQQVKGNKVLLKEIYSWVYKSDVGGSSKSTASSKPKSFKPGQKVTVKKSASKFATGESIADFVKGNSYKVKQVKSDRVLLDGIMSWVRKSDVY
Other Proteins in cluster: phalp2_29156
Total (incl. this protein): 47 Avg length: 314,2 Avg pI: 9,62
Protein ID Length (AA) pI
7qyOK 359 9,63366
169u1 311 9,78309
1k9wz 299 9,69767
1kHkC 350 9,89030
3Y8mC 327 6,60318
71JL2 272 9,88463
7ckJn 441 9,66325
7csT6 334 9,15504
7d9eW 274 9,84975
7dDoW 323 9,79425
7dTfM 324 9,76066
7dfkd 302 9,76356
7dfl4 323 9,60716
7eRuY 369 9,69735
7f7rO 273 9,62830
7fJnw 273 9,69045
7g78G 273 9,71746
7iaRw 272 9,93240
7knIO 273 9,65003
7l8qD 323 9,65396
7mAwX 323 9,66666
7mFSj 273 9,64642
7poiV 334 9,36386
7snpW 314 9,79044
7snun 358 9,58485
7uN1L 323 9,72604
7wMtR 310 8,48386
7wtcs 273 9,71746
7wtjX 323 9,56403
7xM2d 314 9,78612
7xMMX 347 9,85697
7xMv0 323 9,56403
7xMxe 273 9,71682
7xsAl 279 9,66099
7yCKv 323 9,72643
7yTGX 347 9,90313
7yTLa 303 9,70425
7yTQb 273 9,70367
81giP 310 9,59414
8JpG1 356 9,82061
8u1 314 9,77329
VUnu 267 9,87000
iOvB 272 9,98849
nXbH 366 9,64610
uh1q 328 9,51897
A0A1J0MS59 336 9,75595
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1131
3cMm
 37 37,4% 310 2.764E-60
2 phalp2_24835
7sl6i
 39 37,9% 287 7.421E-58
3 phalp2_19215
3ui7r
 7 30,8% 334 2.257E-56
4 phalp2_31516
3ZAQL
 7 28,6% 279 3.228E-41
5 phalp2_22264
7pxLN
 64 31,0% 238 1.262E-37
6 phalp2_14662
5ObrM
 161 25,6% 343 4.753E-26
7 phalp2_30830
8H1gU
 43 28,1% 302 7.011E-25
8 phalp2_36039
5QA7W
 56 27,6% 264 3.622E-22
9 phalp2_22268
7qxva
 11 24,0% 295 1.480E-16
10 phalp2_13856
7rXAX
 3 24,6% 312 2.694E-15

Domains

Domains [InterPro]
Ami2
Unannotated
Unannotated
Unannotated
Representative sequence (used for alignment): 7qyOK (359 AA)
Member sequence: A0A9E7SGB2 (309 AA)
1 359 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage vB_BteM-A9Y
[NCBI] 		2945959 Spizizenvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
ON528935 [NCBI]
CDS location
range 35418 -> 36347
strand +
CDS
ATGGTGAATATTATCCAAGACTTCATTCCGAAAGGAAATAAAAACAGACCAGCATACCCTATGAATCCTCTGTATATTACGGTTCATAATACTTCGAATACTGCAAAAGGTGCGGACGCTGCCAGTCATGCTCGGTATGTTAAAAATCCGGAAACAGCAACCAGCTGGCACTTTACTGTGGATGATGAAAAGATTTATCAACACCTTCCTCTAAATGAAAATGGCTGGCACGCAGGAGACGGAAACGGGACAGGAAACCGTAAATCAATTGGTATTGAAATCTGTGAAAATAGTGATGGGGACTTTGAAAAAGCTGTTTCAAATGCTCAGTGGCTTATCAAGAAATTGATGAAAGAACAGGGGATTTCTTTTGCTAATGTCGTGCCTCATAAACATTGGTCAGGTAAAGAGTGCCCTCGGAAGTTGCTGGACCGTTGGGATTCATTTAAAGCAGGAATCAACGGTGCTGCATCTTCGCCGACAAAAACAGTTAAGAAAACCACCGGAGATACCTACACCGTCAAAAAAGGCGATACACTTTCCGAAATTGCAAAAGAGCACGGGGGGAGTGTGGCAAACCTTCAGAGCTGGAATAACATTAAAGACCCTAATAAAATCACAGTTGGCCAAAAGCTAAAGCTTAAAGGCTCCAGTCCTAAACCAAGCAGCAAAAAAACGTCATATGCGCTGCCTTCTGGCATCTTTAAAGTAACAAACCCTATGAGAAAAGGGGATGATGTAAGGCGGATTCAAAAAGCGCTGGCAGCTCTTTATTTCTACCCGGATAAAGGGGCAAAGAATAATGGCATTGATGGCGTGTATGGTCCGAAAACAGCAAACGCGATCAAACGGTTCCAATCCATATATGGATTGGTTGCTGACGGCATTTACGGACCGAAAACAAAATCAAAATTAAAAGCACTACTATAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0009254 peptidoglycan turnover biological process None (UniProt)
GO:0030420 establishment of competence for transformation biological process None (UniProt)
GO:0030435 sporulation resulting in formation of a cellular spore biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7qyOK) rather than this protein.
PDB ID
7qyOK
Method AlphaFoldv2
Resolution 85.10
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50