Protein

Protein accession
A0A9E7QYW6 [UniProt]
Representative
2Oaoa
Source
UniProt (cluster: phalp2_24217)
Protein name
Lysozyme
Lysin probability
59%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MPKIPTFTAQGSIEQLAGTTTNIQMNLNNNLATALAPVTNTIVNEKIKQNDTQNRTEALRLGNDFIRELQTIEDTIANDNTGLGVNKQSANAYYKEKTNNLIDKFKLQSSNNATATLFTNNALSAVNRGIFRIDNIVDKNVFLDLQNQVEQAETSLITQALFNNKDSNVVDEFGIKGNVNDFDYATLETNLTKLYTDAYSGKIPAANLNKIINNIPSLVQGFQANKDIYDNPSFAYTELNKGENSSVYPDLKVEQRTKLINKVKTMMVQPLQKDFANVIFSLQDKGTEQPFDFNFAKQILPAEKYNELKTTYDLAKINAEDVRLIRTLPLNEADDLIESKNYNTDLYVGSADRITQAKLKEGLINVRNNVVKQMKIDPVQFQIETSPEIAELVSNYENETNPEIKLVNRKILTDAIIDDQIRRGAELDNLKILTKQEVNQIKDQFLNTSVTSEDKLKLIEQLKVTYGYENMGMIVNHLQDEKTSETILMAISTDSVELAKDLFDSSTLKELKTLAAQKDIDVDAIKKLIAKETEDFGQVLDSQGEGSESKAAKMLRINEALLKAALVRTNKNVSVEDAVESASNDFLNDYVINESLTALIPKKINNIDIPVVAALNKSEAILIGLKDTSQGNYLDRFMGEDGYMHYASSLNIPNVSEEEVKKRIGFTIRNYSRWLNNSDMTGMVLYADFGSAGLQPVRNSNGQRIEFYLTDLPNQDPTIKDTISVYPVTNDPLPLIPDPPSDDYFQYDENLIDETIIDEKKNSKFPVDEQSKTDFSFFTKVAAGEATLEDKALANPDLKKRIKKHEGEGKDGLYVPYVDSLGNLTVGHGHKLPKGSTKKKYTKKEIDNFFEEDMKIATKRVNKLGELNLINLNTIDQNAYDILVEMALNMGSNPNAKGKEKKGLFGFKKTLEAIKNGEYKLASEHMLYNFKSKDYKDTSKKIGKTDWYKQVKETRAMTLKNLMASIEEKSQLTNESP
Physico‐chemical
properties
protein length:977 AA
molecular weight:109824,7 Da
isoelectric point:5,16
hydropathy:-0,55
Representative Protein Details
Accession
2Oaoa
Protein name
2Oaoa
Sequence length
232 AA
Molecular weight
26213,79050 Da
Isoelectric point
9,06588
Sequence
TNEIPEGVFGETITSETITNTVDKIKKTDFGIIGDASAAMATKEDKALANPDLKKRIKKFEGVGKKGLNTPYQLEYEKDGKIIKEDFYTVGHGHKLPKGAEIREYSDEEIDNFFEEDMKIATKRVNKLGELNKINLNTIKQDAYDILVEMALNMGSNPNAKPGEKKGLFGFTKTLKAIKAGDYKLASEHMVYNFEGEDYKDISKKIGKTDWYKQVKKNRAMTLKKLMSQIKK
Other Proteins in cluster: phalp2_24217
Total (incl. this protein): 7 Avg length: 870,6 Avg pI: 5,72
Protein ID Length (AA) pI
2Oaoa 232 9,06588
A0A9E7QX49 977 5,15714
A0A9E7QXN8 977 5,15714
A0A9E7QYY9 977 5,15714
A0A9E7QZ16 977 5,15714
A0A9E7U2N2 977 5,15714
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3266
2x3Im
 8 42,0% 221 3.845E-40
2 phalp2_36300
8AlGh
 50 35,2% 187 2.217E-17
3 phalp2_22677
3KYQq
 2 35,7% 151 2.428E-14
4 phalp2_4845
5pl1I
 6 33,5% 173 3.359E-11
5 phalp2_11886
2cyBF
 52 34,4% 186 2.948E-09

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Pelagibacter phage Skadi-2 EXVC102P
[NCBI] 		2971100 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP131299 [NCBI]
CDS location
range 22211 -> 25144
strand +
CDS
ATGCCAAAAATACCTACATTTACAGCACAAGGATCAATAGAACAATTAGCTGGTACTACAACTAATATTCAAATGAATTTAAATAATAATCTTGCTACTGCTTTAGCACCTGTAACAAACACTATTGTTAATGAAAAAATAAAACAAAATGACACTCAAAATAGAACTGAAGCATTAAGATTAGGAAATGATTTTATTAGAGAATTGCAAACTATTGAAGATACTATTGCTAATGATAATACTGGTCTAGGTGTTAATAAACAATCTGCTAATGCTTATTACAAAGAAAAAACAAATAATTTAATTGATAAATTTAAATTACAATCCAGTAATAATGCTACTGCAACTTTATTTACAAACAATGCTTTAAGTGCTGTAAATAGAGGAATTTTTAGAATTGATAATATAGTAGATAAAAATGTTTTTCTTGACTTGCAAAACCAAGTAGAACAAGCAGAAACTTCATTAATAACTCAAGCTCTTTTTAATAATAAAGATTCAAATGTTGTAGATGAATTTGGTATAAAAGGTAATGTAAATGATTTTGATTATGCTACTCTTGAAACTAATTTAACTAAATTATACACAGATGCTTATTCTGGAAAAATACCGGCAGCAAATTTAAATAAAATAATTAATAATATTCCATCTCTTGTTCAAGGATTTCAAGCAAATAAAGATATTTATGATAATCCAAGTTTTGCTTATACAGAACTTAATAAGGGAGAAAACAGTTCAGTTTATCCAGATTTAAAAGTTGAACAAAGAACCAAGTTAATTAATAAAGTTAAAACTATGATGGTTCAGCCATTACAAAAAGATTTTGCTAATGTTATTTTTTCTTTACAAGATAAAGGTACAGAACAACCTTTTGACTTTAATTTTGCAAAACAAATTTTACCAGCAGAAAAATACAATGAATTAAAAACAACTTATGATTTAGCTAAAATTAATGCTGAAGATGTAAGATTAATTAGAACATTACCCTTAAATGAAGCAGATGATCTTATTGAAAGTAAAAATTATAATACAGATTTATATGTAGGATCAGCAGATCGTATAACTCAAGCTAAACTAAAAGAAGGTTTAATTAATGTTAGAAATAATGTAGTAAAACAAATGAAAATTGATCCTGTTCAATTTCAAATAGAAACAAGTCCAGAAATAGCAGAATTAGTTAGTAACTATGAAAATGAAACTAATCCAGAAATTAAATTAGTTAATAGAAAAATATTAACTGATGCAATTATAGATGATCAAATTAGAAGAGGAGCTGAATTAGATAATTTAAAAATATTAACTAAACAAGAAGTTAATCAAATTAAAGATCAATTTTTAAACACATCTGTTACATCTGAAGATAAGTTAAAACTAATAGAACAATTAAAAGTAACTTATGGTTATGAAAATATGGGAATGATTGTTAATCATTTACAAGATGAAAAAACTTCCGAAACAATATTAATGGCTATTTCTACAGATAGTGTTGAGTTAGCTAAAGATTTATTTGATAGTAGCACTTTAAAAGAGTTAAAAACACTTGCTGCTCAAAAAGATATAGATGTTGATGCTATAAAAAAATTAATTGCTAAAGAAACAGAAGATTTTGGACAGGTACTTGATTCTCAAGGAGAAGGATCTGAATCTAAAGCCGCTAAAATGTTAAGAATTAATGAAGCATTATTAAAAGCTGCTTTAGTAAGAACAAATAAAAATGTAAGTGTAGAAGATGCTGTGGAATCTGCATCAAATGATTTTTTAAATGATTATGTTATTAATGAAAGTTTAACAGCATTAATTCCAAAAAAAATAAATAATATAGATATACCTGTGGTAGCTGCTTTAAATAAATCTGAAGCAATTTTAATTGGTTTAAAAGATACTTCACAGGGAAATTATTTAGATCGTTTTATGGGAGAAGATGGATATATGCACTATGCTTCATCTTTAAATATTCCTAATGTAAGTGAAGAAGAAGTTAAAAAAAGAATAGGATTTACTATTCGTAATTACTCTAGGTGGTTAAATAATAGTGATATGACAGGTATGGTTTTATATGCTGATTTTGGTTCAGCTGGATTACAGCCAGTAAGAAATTCTAATGGTCAAAGAATAGAATTTTATCTTACAGATTTACCAAATCAAGACCCTACAATTAAAGATACAATTTCTGTATATCCTGTAACTAATGATCCATTACCTCTTATACCAGATCCACCTTCTGATGATTATTTTCAATATGATGAAAATTTAATAGATGAAACTATTATTGACGAAAAAAAAAACTCTAAATTTCCGGTAGACGAACAATCAAAAACAGATTTTAGTTTTTTTACTAAAGTAGCGGCAGGAGAAGCAACATTAGAAGATAAAGCATTAGCCAATCCAGATTTAAAAAAAAGAATAAAGAAACATGAAGGTGAAGGTAAAGATGGTTTATATGTTCCTTATGTTGATAGTTTAGGTAATCTTACAGTTGGTCATGGACATAAACTTCCTAAAGGATCAACTAAAAAAAAATATACTAAAAAAGAAATAGATAATTTTTTTGAAGAAGATATGAAAATTGCAACTAAAAGAGTAAATAAATTAGGAGAATTAAATTTAATAAATCTTAATACAATAGATCAAAATGCTTATGATATATTAGTTGAAATGGCTTTAAATATGGGAAGTAATCCTAACGCAAAAGGTAAAGAAAAAAAAGGATTATTTGGTTTTAAAAAAACTTTAGAAGCTATAAAAAATGGAGAATATAAATTAGCTTCTGAACACATGCTTTATAATTTTAAAAGTAAAGACTATAAAGATACCAGTAAAAAAATAGGAAAGACAGATTGGTATAAACAGGTTAAAGAAACAAGAGCAATGACACTTAAAAATTTAATGGCTTCAATAGAAGAAAAATCTCAACTAACTAATGAAAGTCCATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2Oaoa) rather than this protein.
PDB ID
2Oaoa
Method AlphaFoldv2
Resolution 85.96
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50