Protein

Protein accession
A0A9E7MR67 [UniProt]
Representative
1Y5Yk
Source
UniProt (cluster: phalp2_28471)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MSKLFSTIFGAVVKATTAPKPAAAKPVPAPVVPKAPTPAPPPPPAPVPPAKPAVELLDIMTLLETAGHEGLVLEAYLDSKKIWTWSIGVTNASGHQVYPRYKDKPQTMEQALTIYEWLMRTKYAPDVHAAFKGHKLTLAQFTAALSFHYNTGAIKTAEWVKAFKRGDLKLAEDQIMNWSSPPEIKGRRRAERDLFFKGVWSNKKGEVTVYPVRKPSYTPDWKNGKVIDLRGPLAAILAKAA
Physico‐chemical
properties
protein length:241 AA
molecular weight:26520,6 Da
isoelectric point:9,81
hydropathy:-0,27
Representative Protein Details
Accession
1Y5Yk
Protein name
1Y5Yk
Sequence length
393 AA
Molecular weight
42024,18880 Da
Isoelectric point
8,88576
Sequence
MSFPPVDYDVALETLSHEGLVRQTYLDSKGVPTWSVGVTSRSGHSVERYYDNPQPMDYCLQVYVWLLRGSYTRDVEAAFKGFTLTKSQFAAALSFHWNTGAIKRAAWVALFKAGKMAQAEAAFMRYSKPPEIMARRKKEADLLFRGRWSNDGRITEYTQVSKSHHIVWSSARRVNIEAALRAALAGDGAPAAAPVSLISQVAPDDAPAIAVPAAGDEIVQSTAGYPAVQQDLKGLGYYDVGIVGDTPGGKTVGAIAAFRLDRGIGGPAVVDDALVLEIAKAKGEGWHRPIADARAQASTQTVAERVPEAKAAKKGVLASWWATFSGGVLTAAAFAKDNISAAKDYITPVTDLAGPVPGWVMIGGVAVALFALYKINASTQDKISDAYRSGERS
Other Proteins in cluster: phalp2_28471
Total (incl. this protein): 4 Avg length: 317,8 Avg pI: 9,50
Protein ID Length (AA) pI
1Y5Yk 393 8,88576
4CEju 396 9,51381
A0A9E7MVD0 241 9,80985
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36335
j9L3
 5 29,4% 367 4.119E-34
2 phalp2_13759
6PI4E
 57 30,1% 262 1.973E-20
3 phalp2_24666
5IWY5
 127 30,0% 250 8.463E-20
4 phalp2_21647
2V9bD
 9 27,8% 262 8.782E-16
5 phalp2_38866
1Mo76
 29 25,0% 259 2.420E-10
6 phalp2_22247
7g4te
 1 25,2% 337 3.472E-06
7 phalp2_1642
8qFOb
 229 25,1% 278 7.579E-05

Domains

Domains [InterPro]
GH24
Unannotated
Unannotated
Disordered region
Representative sequence (used for alignment): 1Y5Yk (393 AA)
Member sequence: A0A9E7MR67 (241 AA)
1 393 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Brevundimonas phage vB_BpoS-Leszy
[NCBI] 		2948602 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
ON529856 [NCBI]
CDS location
range 77361 -> 78086
strand +
CDS
ATGTCAAAACTCTTCTCAACGATCTTCGGTGCCGTCGTCAAAGCCACGACCGCGCCTAAGCCAGCCGCCGCGAAGCCTGTCCCGGCTCCGGTGGTCCCCAAGGCTCCGACGCCCGCTCCACCGCCGCCTCCTGCGCCGGTCCCGCCCGCAAAGCCTGCGGTCGAACTGCTGGACATCATGACGCTGCTGGAAACGGCTGGTCATGAAGGGCTGGTTCTCGAAGCCTATCTGGATTCAAAGAAAATCTGGACGTGGAGCATCGGCGTGACGAACGCCAGCGGGCACCAAGTCTATCCGCGATACAAGGACAAGCCGCAGACGATGGAACAAGCACTGACCATCTACGAGTGGTTGATGCGGACCAAGTATGCGCCGGATGTCCACGCTGCCTTCAAGGGTCATAAGCTTACGCTGGCCCAGTTCACGGCGGCTCTCTCGTTCCACTACAACACCGGCGCGATCAAGACGGCGGAATGGGTCAAAGCCTTCAAGCGGGGTGATCTCAAGCTCGCCGAAGATCAGATCATGAACTGGTCCAGCCCTCCCGAGATCAAAGGCCGCCGCCGGGCAGAACGCGATCTGTTCTTCAAGGGCGTCTGGTCCAACAAGAAGGGCGAAGTCACCGTCTACCCGGTGCGCAAACCCAGCTACACGCCGGATTGGAAGAACGGCAAAGTCATCGACTTGCGAGGCCCCTTGGCCGCCATTTTGGCGAAAGCCGCGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1Y5Yk) rather than this protein.
PDB ID
1Y5Yk
Method AlphaFoldv2
Resolution 78.88
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50