Protein

Protein accession
A0A9E6INB8 [UniProt]
Representative
79roT
Source
UniProt (cluster: phalp2_12276)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MALNGYDISHYQSGLTISKVASDFVILKATEGTTIVDASANNFFSQAKATGRLIGLYHFADTGTAVTQAKYFVNNIKGYLSDKPVLVLDWESTALSQGVAWAKTWLDEVYKLTGVRPLIYMSKSTCNAYNWGSVSANYGLWVAQYASSARTGYQTDPWTDSKGYGTWTNPTIFQYSSSGELSGYSGDLDLDIAYLTKATWAKLGTGSTTEVSTVATITGNKFKVGDYVTVIPKQTKNNTNYDISSWVGAKILIKAVRGKTGAVVYDGVVGTNPYNDLKESNIEAYIDPATVNPLFKVGDQVQISPNASKEYDEYDLTPRHYKVGTIAAVTKLKAKYSRSWFNYGVKYTDGTHNTTVLEQDLVW
Physico‐chemical
properties
protein length:363 AA
molecular weight:39840,1 Da
isoelectric point:7,65
hydropathy:-0,26
Representative Protein Details
Accession
79roT
Protein name
79roT
Sequence length
338 AA
Molecular weight
36542,02510 Da
Isoelectric point
4,14501
Sequence
MLNGIDISNYQADLNAGLIGADFVIVKATEGLDYINPVADQHYQQAKTAGKLLGVYHFMTADDPRAQAEFFVNNVDGYVGEAVLVLDFEAGGLALGSNGAKVFLDRVKELTGVAPLIYMSKCTINQMDWSAVAPEYGLWAAQYANYARTGYLSDPWTDDTGWGVWGQPALFQYSSSGALNGYAGNLDLDIAYMDADAWHKFAGKDTANPDINNGPQPQPNKVVDQVLNVGDNFSFADQIYRVDELSASRDEFISNELAGGTDGIWENNGVPAALVDEVTVGTLSAEGQDQVLQVGSYAKFKKTEPWTVLEVNAESNGVKVDTDGYGTLWLDATTLTKI
Other Proteins in cluster: phalp2_12276
Total (incl. this protein): 46 Avg length: 285,8 Avg pI: 5,57
Protein ID Length (AA) pI
79roT 338 4,14501
1Kw1D 331 5,90986
1oiHr 222 5,10934
23zwD 340 5,53068
24kZL 290 5,41968
3WIJd 290 5,06205
3ZCeA 290 5,85802
3ZZfD 290 5,07984
3fTRt 291 6,12153
3fVHt 264 4,96008
3gXMw 305 6,73937
3iZKk 297 5,66511
405fF 299 5,75094
40k8s 291 5,86666
41nX7 319 6,40294
41oFG 292 5,69586
4MigC 291 6,74050
4MkAq 215 5,74150
4VVgz 333 5,09547
4kfOi 288 5,03204
4kqc0 258 4,64263
5Nfww 222 5,12247
5ToEi 222 5,01822
6bNFq 222 4,98435
6baUM 222 5,15037
6d0l5 222 5,00163
6gvlz 222 5,00163
6i5WV 295 9,29997
6iCFP 222 4,88442
6kbZo 222 4,86965
72hmU 334 6,16620
73ZKo 333 5,10678
73fh9 334 5,78419
749lI 317 4,71431
76Xrb 330 5,08603
78KAV 332 4,50582
7DEYu 289 5,34812
7DGsX 216 4,72459
7DKVm 242 6,72999
7Z6Zs 279 9,23447
7bPuz 311 4,66645
7qzww 338 4,41943
7wD7r 339 4,17257
8vrMm 222 5,00163
A0A6S4IQL3 363 6,90198
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37341
8v6XY
 562 50,2% 221 5.669E-98
2 phalp2_4274
8cjfF
 9 48,0% 210 1.491E-77
3 phalp2_16579
7zIOC
 8 39,6% 242 1.413E-71
4 phalp2_32821
2L8bh
 41 46,7% 233 6.009E-70
5 phalp2_27394
4HDMm
 9 47,0% 221 2.452E-65
6 phalp2_36024
5HOPw
 12 37,1% 207 8.725E-55
7 phalp2_22768
8hiL6
 3 34,9% 209 2.661E-53
8 phalp2_24845
7umqo
 6 38,4% 229 3.191E-52
9 phalp2_35154
5HNke
 1 29,8% 231 2.241E-47
10 phalp2_30061
2NCcc
 23 33,6% 229 6.939E-44

Domains

Domains [InterPro]
GH25
Unannotated
Representative sequence (used for alignment): 79roT (338 AA)
Member sequence: A0A9E6INB8 (363 AA)
1 338 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Oenococcus phage Vinitor-27
[NCBI] 		2769357 Aliceevansviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MT859305 [NCBI]
CDS location
range 23275 -> 24366
strand +
CDS
ATGGCTCTAAATGGATATGATATTTCACATTATCAATCTGGTTTAACAATTTCTAAAGTTGCCAGTGATTTTGTGATTTTAAAAGCAACCGAAGGCACAACAATAGTTGACGCTTCGGCTAACAATTTCTTTTCACAGGCGAAGGCGACTGGTCGTTTAATTGGTTTATATCATTTTGCTGATACTGGAACAGCAGTCACTCAAGCCAAATATTTTGTGAATAATATAAAAGGCTATTTGTCCGATAAACCAGTTTTGGTTCTTGATTGGGAATCAACGGCTTTATCTCAAGGTGTTGCATGGGCTAAGACATGGCTTGATGAAGTTTATAAATTAACTGGAGTTCGTCCTCTGATTTATATGAGCAAATCAACATGTAATGCTTATAATTGGGGCTCTGTTTCTGCAAATTATGGTTTGTGGGTTGCTCAATATGCTTCAAGTGCTCGCACAGGCTATCAAACAGACCCATGGACTGATTCTAAAGGTTATGGTACATGGACAAATCCTACAATCTTTCAATATTCGTCTAGTGGAGAATTAAGCGGTTATTCTGGCGATCTTGATCTTGACATTGCCTATTTGACTAAAGCGACTTGGGCGAAATTAGGAACAGGAAGCACAACGGAGGTTTCAACAGTGGCAACAATTACAGGAAATAAATTTAAAGTTGGCGATTATGTAACCGTAATTCCTAAACAAACTAAAAATAATACAAACTACGATATTAGTTCGTGGGTTGGTGCAAAGATTTTAATTAAGGCTGTACGGGGAAAAACAGGCGCTGTCGTTTATGATGGCGTAGTTGGTACTAATCCATACAACGATCTAAAAGAAAGCAATATCGAAGCATATATTGACCCTGCAACGGTTAATCCTTTATTCAAAGTTGGAGACCAAGTACAAATCAGTCCAAATGCGTCTAAAGAATATGATGAATATGATTTAACGCCACGACATTATAAGGTTGGTACAATTGCCGCAGTTACTAAATTAAAAGCTAAATATTCTCGTTCATGGTTCAATTATGGAGTCAAATATACAGATGGCACTCACAATACAACTGTTCTTGAACAAGATTTAGTATGGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (79roT) rather than this protein.
PDB ID
79roT
Method AlphaFoldv2
Resolution 87.93
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50