Protein

Protein accession
A0A915YA39 [UniProt]
Representative
3g7XB
Source
UniProt (cluster: phalp2_34268)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MDNNIRKKLIAMGLSGAIALGGALLAPFEGKVNKVYVDPVGILTSCYGHTGPELKKGQQFTDSQCLDQLAKDLLEHNKILTNVVKVELTPYEHAAFLSFLYNVGPGKKGVKDGFVTLKNGNQSTMLRKLNAGDKVGACNELLKWTKAGGVVLKGLVKRRTEERNVCLGNLN
Physico‐chemical
properties
protein length:171 AA
molecular weight:18511,4 Da
isoelectric point:9,45
hydropathy:-0,16
Representative Protein Details
Accession
3g7XB
Protein name
3g7XB
Sequence length
267 AA
Molecular weight
27944,74770 Da
Isoelectric point
6,92512
Sequence
MKASLKAYALAKGYEGWSAVPYLCPGGKWTIGWGHTQGVTAHTPAITEAQGELYLAHDIIEAERIVERAVTVSLNQNEFDALVLFVMNSGPGQAGVKSGLAELKTGGPSTLLRRLNENDRAGAAAEWLKWVYAGGQKLPGLIIRRAEERALFLAPVMAAETAPEPRLPSPGPSVWSRVAAIWAVLMRGRELAGAEAWKNRQAAASALTAILGALAPFLPIEVSNEDLLAIAGGVAAVGGLLNAYLVLATSRRVGVPAGGEPAHDSAG
Other Proteins in cluster: phalp2_34268
Total (incl. this protein): 9 Avg length: 203,1 Avg pI: 8,61
Protein ID Length (AA) pI
3g7XB 267 6,92512
4gTio 267 7,86780
89J0s 268 6,64086
A0A4Y5JTU3 171 9,26341
A0A5E3ZZ40 171 9,26341
A0A915YA89 171 9,44824
A0AA51BKW8 171 9,44824
A0AAX4QCH0 171 9,14189
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28113
7zmZV
 50 43,0% 165 1.153E-38
2 phalp2_2498
5GMvl
 297 38,2% 235 6.554E-37
3 phalp2_29738
1pBjt
 830 43,6% 172 3.096E-36
4 phalp2_26378
1q5mp
 207 42,1% 173 1.664E-27
5 phalp2_18125
4eVlm
 2 38,5% 184 2.642E-24
6 phalp2_35656
1rvIk
 44 36,9% 165 3.056E-23
7 phalp2_33932
23JqA
 85 36,0% 169 7.645E-23
8 phalp2_23227
7HiLX
 27 37,2% 177 1.911E-22
9 phalp2_22286
7A6Fj
 714 31,0% 174 6.477E-22
10 phalp2_29204
865D
 1 37,3% 166 6.477E-22

Domains

Domains [InterPro]
GH24
Disordered region
Representative sequence (used for alignment): 3g7XB (267 AA)
Member sequence: A0A915YA39 (171 AA)
1 267 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Pseudomonas phage sp. 30-3
[NCBI] 		2972143 Arenbergviridae > Wroclawvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LC727698 [NCBI]
CDS location
range 76233 -> 76748
strand -
CDS
ATGGATAATAATATTAGAAAAAAATTAATTGCAATGGGATTATCCGGTGCAATTGCACTAGGAGGAGCACTATTGGCTCCGTTTGAAGGTAAAGTAAACAAGGTATATGTAGATCCAGTAGGAATTTTAACATCTTGCTACGGTCACACTGGACCTGAGCTAAAAAAAGGACAACAATTTACAGACAGCCAATGTTTGGATCAATTAGCAAAAGATCTTTTAGAACATAATAAAATCTTAACAAATGTAGTAAAGGTAGAATTAACGCCATACGAACATGCTGCGTTTCTTTCGTTCTTATATAACGTAGGACCAGGGAAAAAAGGGGTTAAAGACGGATTTGTCACATTAAAAAATGGAAATCAATCCACAATGCTTAGAAAATTAAATGCAGGCGATAAAGTAGGAGCATGCAACGAATTGCTAAAATGGACTAAAGCAGGAGGAGTTGTTTTAAAAGGATTAGTAAAACGAAGAACTGAAGAGAGGAATGTATGTTTAGGAAACTTAAATTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016020 membrane cellular component None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0020002 host cell plasma membrane cellular component None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID
A0A915YA39
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0A915YA89
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0AA51BKW8
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (3g7XB) rather than this protein.
PDB ID
3g7XB
Method AlphaFoldv2
Resolution 75.46
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50