Protein

Protein accession
A0A8S5VYD9 [UniProt]
Representative
3WCZQ
Source
UniProt (cluster: phalp2_31510)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSKLYLDISHHHRVKNWTELEKSCPFLITKATEGQTFVDSYFPVVVNECEKRKIPYFLYTFLRRGNVKKQINYLVDKVNKVKGSNFIGYCLDIECGNSAEEVQEAVNYLDEIWTGKKLFYYMYADYGKYKNTIKNLDKNTWCVWEARYGRNTPKYNKSYPPHEIADFHQFASGVRIPFMTGGIDVNRLTGSKPESWFCTKKKVKAGYFKRCSKEQTSIIAGLKENGYKSNYNYRSLIAQVNNIKNYAGTAKQNIKMLDMLKAGKLAKPL
Physico‐chemical
properties
protein length:269 AA
molecular weight:31249,6 Da
isoelectric point:9,49
hydropathy:-0,59
Representative Protein Details
Accession
3WCZQ
Protein name
3WCZQ
Sequence length
462 AA
Molecular weight
52835,75290 Da
Isoelectric point
8,26802
Sequence
MVLYPDISHYHPVIDWDKVKKECGVLISKATQGTSFVDKTLDDFIRGCEKYKIPYWLYTYLDKGNEKAQAEFLVSTCKNRVGDYFVGYILDVEEHNDADNVRAALDYLSTQSAKTMVYTMYSEYQKYSALVAKRPNTCAWWEARYGRNNGSFDRTFDCHVGADFHQYSSEGYVSGIGFHVDLNRPTGSKPLDFFTTPSNVKTNTRSEENKVVRVGSARIDENGRAHSGKAGDQTGKEVAIENWYLHNKGWFVIRAKDAIKRDRIAKNMEYACNNPNIGYDQYQNQTLWNVVKQVGFDCSKVTTKCETDCARLVRVCVWYAGVQAQDFYTATELQTLKDTGQFEILTSDKYCKSSDYLMRGDILVTRSKGHTVVVLDNGAKIESAQKKGGEEMQCTYTVDKKGTVYWFDGHASRTLSHPDQLKIVRQIYKANNGIDLPHYDWTSKAPWYIRLQQAANAPEKKW
Other Proteins in cluster: phalp2_31510
Total (incl. this protein): 5 Avg length: 390,0 Avg pI: 8,13
Protein ID Length (AA) pI
3WCZQ 462 8,26802
1Je9R 481 5,05182
3e0he 371 8,90304
4015e 367 8,95448
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37217
23tRW
 1 27,9% 426 2.446E-41
2 phalp2_4274
8cjfF
 9 25,1% 306 6.938E-21
3 phalp2_37225
24mkV
 7 20,1% 393 3.020E-13

Domains

Domains [InterPro]
GH25
Unannotated
Unannotated
Representative sequence (used for alignment): 3WCZQ (462 AA)
Member sequence: A0A8S5VYD9 (269 AA)
1 462 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Tectiviridae sp
[NCBI] 		2831614 Kalamavirales > Tectiviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK031033 [NCBI]
CDS location
range 8693 -> 9502
strand +
CDS
ATGAGTAAATTATATCTCGACATTAGCCATCATCATAGAGTTAAAAATTGGACAGAACTTGAAAAAAGTTGTCCGTTTTTAATCACAAAAGCAACTGAGGGACAAACATTCGTGGACAGCTATTTTCCTGTAGTTGTCAACGAATGTGAGAAAAGGAAAATTCCTTATTTTCTGTACACATTTTTACGAAGAGGAAATGTTAAAAAGCAGATTAACTATTTAGTTGACAAAGTAAACAAGGTAAAAGGTAGCAATTTTATCGGATATTGTTTAGATATTGAATGTGGAAACAGCGCAGAAGAAGTGCAAGAAGCCGTTAACTATCTCGATGAAATCTGGACAGGTAAAAAGCTGTTTTACTATATGTATGCCGATTATGGCAAATACAAGAACACGATTAAAAATCTGGATAAAAATACATGGTGTGTATGGGAAGCACGGTATGGAAGAAATACTCCTAAATATAATAAGTCATACCCACCTCATGAAATTGCAGATTTCCACCAGTTCGCCAGTGGTGTGAGAATCCCATTCATGACAGGCGGTATTGATGTTAACCGACTGACGGGAAGTAAGCCAGAAAGCTGGTTTTGTACGAAGAAAAAAGTCAAAGCTGGTTATTTCAAAAGGTGTTCAAAAGAACAGACGAGTATTATCGCAGGCTTGAAAGAAAATGGTTATAAATCTAATTATAACTATCGGTCACTCATTGCACAGGTAAACAATATCAAAAACTATGCAGGAACAGCGAAACAAAATATCAAAATGCTGGATATGTTAAAAGCTGGAAAACTTGCAAAACCGTTATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3WCZQ) rather than this protein.
PDB ID
3WCZQ
Method AlphaFoldv2
Resolution 90.80
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50