Protein

Protein accession
A0A8S5VL13 [UniProt]
Representative
6o0Aa
Source
UniProt (cluster: phalp2_23424)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MAQTGIFNGRTRVRYGYARWGWTRGGGKTWHGGIDVCGLDDDKIRMPGYNGKSIAGTVVTARIVTNKSNKTWEWGYYICVKLDANQTPDAVNYLYFCHCSKLLASVGQKVKTGDVLAVVGQTGNAAGTWTHCHFEVRATATSKGLDPTAYAGILNKAGTYGDQPAQTSGEEVLIDVSHHQGAIDWAKVPYRAIVRIGYRGYGTGKLMKDEQYDANLAGAKANAKLFGFYFFSQAITVDEAREEADFCAGLAPSGYPLFFDAEWSHETHDGRADSLTKDQRTAIAMAFCERAKAHGFAAGIYTFTAFASANIDYTYLCEDYIGWLADTRTNYDKTLPRHIHQYGQAAKGSVPGITDVVDLNHLVKALPTVGKPERKLQVITIGPVSQGDADAIYLLCKERGLTDAGLYKSEWAEV
Physico‐chemical
properties
protein length:414 AA
molecular weight:45283,4 Da
isoelectric point:7,16
hydropathy:-0,29
Representative Protein Details
Accession
6o0Aa
Protein name
6o0Aa
Sequence length
205 AA
Molecular weight
21883,65490 Da
Isoelectric point
9,20971
Sequence
MLFTGRNLVKYDYSRYGYTRGGGKTWHGGLDIGGLDDAKIRMPGYNSKSISGTVVTARIVTDKSNKTWEWGWYVCVKLDANQTPDAVNYLYFCHCSKLLVKVGQKVKTGDVLAIVGQTGNAAGTWTHCHLEVRATATGKGLDPTAYAGIPNKAGTYGAAPAPAAAKLQTITIGPVSQGDADAVYAVCKQRGLTDAGLYKSVWVEA
Other Proteins in cluster: phalp2_23424
Total (incl. this protein): 95 Avg length: 229,5 Avg pI: 7,95
Protein ID Length (AA) pI
6o0Aa 205 9,20971
139Ky 166 6,80052
1FDSO 217 5,92060
1FW2t 217 5,92060
1mMuk 202 9,09805
1n2IV 202 9,22364
1n7xd 207 8,94062
1nhF4 207 8,94062
1nnIV 257 8,57450
1o8n0 218 9,08335
1odqP 207 9,47526
2meoj 218 7,60207
2mien 218 8,46085
3l8TS 207 9,00677
3lXjX 189 6,43317
3lclQ 207 8,77197
3lhkZ 207 9,02224
3m7ld 202 9,09805
3mlJ5 261 6,12238
3mn4u 207 9,02224
3muX6 218 7,60207
3p08D 265 5,45992
3p30J 261 6,12238
3psVV 257 7,01901
3qHSv 262 6,29307
3qPPp 257 7,66277
3rZo4 207 9,35883
3sSSB 218 8,15939
3tCgq 207 9,23311
3tHNd 202 9,12384
3uJuf 218 8,15939
3uU12 261 6,12238
3uWTJ 207 9,09541
3udPr 257 8,37394
3ufx5 207 8,94062
3uzJ1 310 5,59275
3v2Fz 207 9,02256
3vAPB 207 9,23292
3vSWi 291 6,59420
3vuCm 202 9,09805
3wnY0 257 8,73329
3wnvO 202 9,09805
3x1gS 262 6,49075
3x8MA 207 9,21410
3xIi0 207 9,58485
3xwum 262 8,48928
3xyJc 261 6,12238
5BZRi 204 9,12390
5QAAr 217 7,64930
5Sj8N 199 8,79157
5otiO 279 9,03707
65KUu 195 7,63407
66s9O 262 8,07268
678nZ 181 7,66851
67ysD 202 9,12384
69dEO 163 8,96937
6ZXw0 236 8,54691
6cU56 216 7,65834
6djUA 217 6,95660
6eLRy 262 8,68610
6evnx 262 7,62958
6gUZu 217 8,17635
6hVLM 262 8,17822
6isPm 214 8,84392
6it2p 203 9,30023
6lfGv 217 7,61838
6pfF0 262 8,67843
6rOE4 205 9,30023
6sGwx 217 7,60406
6tQVB 217 7,64282
6tpab 217 6,95297
6vq1N 210 7,61775
76ow5 266 5,86416
76owr 263 5,95220
7WECk 164 9,45082
7Y6kY 249 6,58647
7ZJBH 166 8,98955
7apps 207 8,85185
7fTie 221 8,08687
7xU1W 310 6,10408
8bLnR 168 8,55271
8cF6r 216 6,07821
8fOfh 207 9,09522
8jEfB 213 8,94410
8kldL 259 8,52815
8l5sx 258 6,42124
8ovsZ 294 5,90315
8pchS 294 7,56859
8rjH5 185 8,20407
8vrPb 284 4,92586
KIqS 216 7,65481
ZJmU 192 7,09921
A0A8S5MYV0 412 6,01700
A0A8S5RU12 206 9,07310
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27617
61iMz
 5 64,4% 177 3.622E-91
2 phalp2_14691
6phH8
 2 66,6% 126 4.989E-65
3 phalp2_22440
Otxz
 62 59,5% 163 3.422E-58
4 phalp2_5933
67ENK
 29 45,5% 145 5.949E-36
5 phalp2_665
1mzrw
 14 38,6% 150 7.444E-27
6 phalp2_5213
453FH
 7 29,8% 161 9.225E-19
7 phalp2_7513
4USyj
 3 32,9% 161 8.012E-18
8 phalp2_9504
10yNL
 1 32,0% 150 1.284E-16
9 phalp2_34795
3yVyS
 22 34,4% 154 4.396E-16
10 phalp2_18215
4MgOJ
 3 29,5% 203 2.377E-14

Domains

Domains [InterPro]
PET_M23
Unannotated
Representative sequence (used for alignment): 6o0Aa (205 AA)
Member sequence: A0A8S5VL13 (414 AA)
1 205 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Ackermannviridae sp
[NCBI] 		2831612 Ackermannviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK035285 [NCBI]
CDS location
range 13625 -> 14869
strand +
CDS
ATGGCGCAGACAGGAATCTTTAACGGACGGACGCGCGTGCGGTATGGCTACGCGCGGTGGGGCTGGACGCGCGGCGGTGGCAAGACTTGGCACGGCGGCATTGACGTTTGCGGGTTGGATGACGACAAAATCCGCATGCCCGGCTACAACGGCAAGAGCATTGCAGGAACCGTTGTTACAGCCCGCATCGTGACGAACAAGAGCAATAAGACATGGGAATGGGGCTATTATATCTGCGTGAAGCTGGACGCAAACCAGACCCCGGATGCAGTGAATTACCTGTATTTTTGCCACTGCTCCAAGTTGCTTGCAAGCGTAGGGCAGAAAGTAAAGACCGGCGATGTGCTGGCGGTTGTCGGACAGACTGGCAACGCCGCAGGCACATGGACGCACTGCCACTTTGAAGTGCGAGCCACTGCCACGAGCAAGGGCCTTGACCCGACTGCGTATGCAGGCATACTCAACAAGGCGGGCACATACGGCGACCAGCCTGCGCAGACAAGTGGCGAAGAAGTGCTGATTGATGTGTCTCACCATCAGGGCGCTATCGACTGGGCAAAGGTTCCCTACCGTGCCATTGTTCGCATCGGCTATCGCGGCTACGGCACCGGAAAGCTGATGAAGGACGAGCAGTACGATGCCAACCTTGCAGGGGCGAAAGCGAACGCAAAGCTGTTCGGCTTTTACTTCTTCTCGCAGGCCATCACGGTGGACGAAGCCCGCGAGGAAGCAGACTTCTGCGCAGGCCTTGCCCCGTCTGGATACCCGCTGTTTTTTGATGCCGAGTGGAGCCACGAGACGCACGATGGCCGCGCCGACAGTCTGACGAAAGACCAGCGCACGGCAATCGCAATGGCGTTCTGTGAGAGGGCCAAAGCGCACGGATTCGCGGCAGGCATCTACACCTTCACGGCCTTTGCAAGCGCAAACATCGACTACACCTACCTGTGCGAGGATTACATCGGCTGGCTTGCCGACACGCGCACAAACTACGACAAAACGCTTCCGCGCCACATCCACCAATATGGGCAGGCTGCGAAGGGAAGCGTGCCGGGCATCACTGACGTGGTTGATTTGAACCATCTGGTCAAAGCTCTGCCTACGGTGGGCAAGCCCGAAAGAAAGCTACAAGTGATTACCATCGGGCCGGTATCGCAGGGGGACGCAGACGCGATTTATCTGCTGTGCAAGGAACGCGGCCTGACGGACGCTGGACTGTACAAATCTGAATGGGCGGAGGTGTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6o0Aa) rather than this protein.
PDB ID
6o0Aa
Method AlphaFoldv2
Resolution 94.73
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50