Protein

Protein accession
A0A8S5VJ05 [UniProt]
Representative
86zOP
Source
UniProt (cluster: phalp2_25276)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MEGVDVSKYQGTIDWHEVKASGMGFAMVRQGWINSDGSITEDPFYRQNMAEAHAAGLHTGVYLYSYCTSESAMKVAASACVAMLEGFVCDMPIALDFEHATLYKRFSRAANASLCAAFLSRIEELGRYCILYTYKSFAAAYLDMSALSRYDFWLAHYTARTDYTGPYGMWQYTSSGTVPGISGRVDCNHAYKDYPALIAGEKKEDTPMSDMLKVGPVSGGDRKTMAALADSLGLPHEDAGDYLIIGPASAGDRKAIAAKAAALAVGCVEYTAPEPEPEPKPEPTPAPTPAPDSGKDDTAACTEQLGRIEAKLDKLLGLVNPSLLEG
Physico‐chemical
properties
protein length:326 AA
molecular weight:35069,3 Da
isoelectric point:4,93
hydropathy:-0,18
Representative Protein Details
Accession
86zOP
Protein name
86zOP
Sequence length
360 AA
Molecular weight
38588,05700 Da
Isoelectric point
5,69654
Sequence
MEQNGIDVSKYQNAIDWPRVAASGVCFVFVRVGWAGYEGGIDEGLDPCFARNMTGAAAAGLAVGAYVYSYCKTPAAARRAAREAAALLAPYRLTMPLVFDIEDAATYKALGRAQSSAVAAAFLEEAKARGYYPLLYTYTSFAQSYLDMSALSAYDLWLADYRGYMGLKGASIWQHTSDGRVDGINGRVDLNIAYKDYPALIGRQGGQKEDKNDMMNFLEVFGEKNCQCFTGPDVNAVDRSYNNGTLASGTYYPLMADCGLGDDGYRWVRVLAGGAERYAVVLDDRCRITGLSAGDAVRAVQAQGAGGDAALTRRVKELESSNAGLLARASAAEAQSAEAARRAAQYLKRIKAAAAALEVL
Other Proteins in cluster: phalp2_25276
Total (incl. this protein): 11 Avg length: 340,1 Avg pI: 5,19
Protein ID Length (AA) pI
86zOP 360 5,69654
7phf9 337 4,73812
86rII 360 5,69654
8eUvk 337 5,20892
8lUhE 360 5,68796
8vPFj 359 5,41263
A0A8S5QN69 325 4,80951
A0A8S5UK76 324 5,01584
A0A8S5VKS8 323 4,98821
A0A8S5VXI0 330 4,92632
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_35314
79Mal
 26 35,6% 230 2.743E-36
2 phalp2_37848
4L2Bj
 9 37,1% 226 1.441E-34
3 phalp2_24673
5KMWz
 154 31,5% 266 5.212E-31
4 phalp2_30592
67VKs
 21 30,8% 237 2.945E-28
5 phalp2_26020
6SL2Q
 7 26,4% 272 3.245E-19
6 phalp2_10721
3dVAF
 2 25,3% 245 2.058E-13
7 phalp2_18592
7pcZx
 1 24,7% 299 1.513E-11
8 phalp2_30879
zkiN
 42 27,1% 258 1.845E-08

Domains

Domains [InterPro]
GH25
Unannotated
Unannotated
Representative sequence (used for alignment): 86zOP (360 AA)
Member sequence: A0A8S5VJ05 (326 AA)
1 360 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Ackermannviridae sp
[NCBI] 		2831612 Ackermannviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK035228 [NCBI]
CDS location
range 12472 -> 13452
strand +
CDS
ATGGAGGGCGTTGACGTCTCGAAGTATCAGGGCACCATCGACTGGCACGAGGTGAAAGCATCCGGTATGGGCTTTGCCATGGTGCGGCAGGGGTGGATTAACTCGGACGGCAGCATTACTGAGGATCCTTTTTACCGCCAAAACATGGCCGAGGCACACGCTGCGGGCCTGCACACCGGCGTGTATCTGTACAGCTATTGCACATCCGAAAGCGCCATGAAGGTAGCTGCAAGCGCTTGTGTGGCCATGCTGGAAGGATTTGTGTGCGATATGCCCATCGCTCTGGACTTTGAGCACGCCACGCTGTACAAGCGCTTTTCGCGGGCCGCAAATGCCAGCCTCTGCGCGGCCTTTTTGAGCCGCATTGAGGAGCTGGGGCGCTATTGCATCCTGTACACCTACAAGTCTTTCGCGGCGGCGTATCTGGACATGAGCGCCCTGAGCCGCTATGATTTTTGGCTTGCCCACTACACCGCCCGCACGGACTACACCGGCCCCTATGGGATGTGGCAGTACACCAGCAGCGGCACTGTGCCGGGCATTTCGGGGCGTGTAGACTGCAACCACGCTTACAAGGACTATCCGGCACTTATCGCCGGAGAAAAGAAGGAGGATACACCCATGAGCGATATGCTGAAAGTAGGCCCGGTTTCGGGCGGCGACCGCAAGACTATGGCAGCCCTGGCGGACAGCCTGGGCCTGCCCCACGAGGATGCGGGCGACTATCTCATTATCGGCCCCGCCAGCGCAGGCGACCGGAAGGCCATTGCCGCAAAGGCTGCTGCTCTGGCGGTGGGCTGCGTGGAGTATACCGCGCCCGAACCGGAACCTGAACCCAAGCCGGAACCCACGCCTGCCCCCACTCCGGCCCCGGACAGCGGCAAAGACGACACCGCCGCCTGCACCGAGCAGCTGGGCCGTATCGAGGCAAAGCTGGACAAGCTGCTGGGGCTGGTGAACCCCAGCCTGCTGGAGGGCTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (86zOP) rather than this protein.
PDB ID
86zOP
Method AlphaFoldv2
Resolution 86.71
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50