Protein

Protein accession
A0A8S5VCS6 [UniProt]
Representative
2BOY
Source
UniProt (cluster: phalp2_8261)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MPEIKGIDVSRWNGKIDWKTVANYGMGFAILRITEKGNIIDSTFEPNYKGCIENKIPVGVYKYSYATTIAQIKNEANVVIKTLNKRKLDYPVFLDIEDKCQENLSDNLMMKMIEAFRAIIVKAGYKFGIYCGYSWYQYQLPEGAKKYDCWVARYPNNDTGELQERLRVPASTGVIGWQYSSKATIPGIPTKTDRSVFYKDYSKSSTTSTNSLKPTTTQGSDTMNKDKAIDALIACAENEVGYLEKKSNSQLDDKTANVGYNNYTKYWRDVYPQYQAQAWCAAFVSWCMMKTFGLDVAKKLLKHWPYVYCPTLGNLFTKYANPQRGDIVIFYRNGTFAHTGLVTKVEGDKFYTIEGNTSGGSSIVPNGGGVYAKSYYNSNLPGTKFCRPDYSIVTSILTSNTSSTSSPAPVQPSYTAWVGSCTANGTDVFSGATGASKLSTYPKLNAGNLVDIIGESGTRYQVRIAAKYIGYVEKSNIKNPNTPAATTTKKYPFVGKVTASKLNVRKKPGTEHPLLPEYPMLNKDNLVNVLGVTKDTKGDRWYKVSITKKEYVGYVSAKYIIKA
Physico‐chemical
properties
protein length:563 AA
molecular weight:62747,7 Da
isoelectric point:9,33
hydropathy:-0,43
Representative Protein Details
Accession
2BOY
Protein name
2BOY
Sequence length
326 AA
Molecular weight
36328,60750 Da
Isoelectric point
7,62463
Sequence
MNKTDAINRMISIAQNEKGYLEKASNSNLDDKTANAGSGNYTKYWRDVKPEWNGQAWCACFVTWVLQQAFGKEYAEKLLKHYPYVYVPTLMNLFTRYANPEKGDIVCFYRNGSFTHTGIVISVSGDYFQTIEGNTSGASGIIANGGGVCQKGYYNSQLPGTKFARLDWSIVADYGHKEEVKMVQKPGDKAYSENRINYRVHQQSVGWLPHVEDGQVAGVTGFSKRIEAIKIDCKMPGVKIHAKGHIQGIGWKDYGEITSDTVIGTTGQEKRLEAISLEAEGLPDGMNIYVRYHIETEGWSDWIKGGTVAGTVGLEKRLEAIQIKIQ
Other Proteins in cluster: phalp2_8261
Total (incl. this protein): 2 Avg length: 444,5 Avg pI: 8,48
Protein ID Length (AA) pI
2BOY 326 7,62463
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_774
21gG8
 241 40,6% 231 9.582E-38
2 phalp2_20810
62jU5
 13 37,5% 229 1.987E-30
3 phalp2_34844
3WDOv
 50 35,1% 233 1.494E-25
4 phalp2_15705
3dUPZ
 2 33,0% 224 4.031E-17
5 phalp2_22287
7C3Cm
 23 28,3% 208 8.328E-09
6 phalp2_32084
62aVI
 2 22,0% 245 9.276E-04

Domains

Domains [InterPro]
CHAP
ChW
Representative sequence (used for alignment): 2BOY (326 AA)
Member sequence: A0A8S5VCS6 (563 AA)
1 326 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257, PF07538

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctDXu9
[NCBI] 		2825387 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK016244 [NCBI]
CDS location
range 27384 -> 29075
strand -
CDS
ATGCCAGAAATCAAAGGTATTGATGTTTCCAGATGGAATGGAAAAATCGACTGGAAAACCGTTGCTAATTATGGAATGGGCTTCGCTATCCTACGAATCACAGAAAAAGGAAATATTATTGATAGCACATTCGAACCTAATTATAAAGGCTGTATTGAGAATAAAATTCCTGTTGGAGTCTATAAATACAGCTATGCTACTACTATTGCTCAGATTAAAAATGAAGCAAATGTAGTTATTAAAACATTGAATAAAAGAAAACTGGATTATCCAGTGTTTCTTGATATAGAGGATAAATGTCAGGAGAATTTATCTGACAATTTAATGATGAAAATGATCGAAGCGTTTAGAGCTATTATTGTCAAAGCTGGATATAAATTTGGTATTTATTGCGGCTATTCTTGGTATCAGTATCAACTACCAGAAGGTGCTAAAAAGTATGATTGTTGGGTTGCCCGATATCCTAATAATGATACCGGTGAATTACAGGAAAGATTAAGAGTTCCTGCTTCTACTGGTGTTATTGGATGGCAATATTCTAGTAAGGCAACCATTCCTGGAATTCCAACAAAAACCGATCGAAGTGTATTCTATAAAGACTATTCTAAATCTTCTACTACTTCTACAAACTCTCTCAAACCAACAACTACACAAGGAAGTGATACTATGAATAAAGATAAAGCTATTGATGCTCTTATTGCTTGCGCTGAAAATGAGGTTGGATATTTAGAGAAGAAATCTAATTCTCAGCTTGATGATAAAACTGCAAATGTAGGTTACAATAACTACACTAAATACTGGAGAGACGTATATCCTCAGTATCAGGCACAGGCTTGGTGCGCTGCATTTGTGAGCTGGTGTATGATGAAAACATTCGGTCTTGATGTAGCTAAAAAACTCCTTAAACATTGGCCTTATGTATACTGTCCTACTCTTGGAAATCTCTTCACAAAGTATGCAAATCCACAGCGAGGAGACATTGTAATCTTCTATCGTAATGGTACATTCGCTCATACTGGATTAGTAACAAAAGTCGAAGGAGATAAATTTTATACTATTGAAGGTAACACTTCAGGAGGCTCTTCTATTGTTCCAAATGGTGGTGGAGTTTATGCTAAGAGTTATTATAATTCAAATCTCCCTGGGACAAAGTTTTGTCGTCCAGACTATTCTATTGTCACATCCATCTTAACTTCTAACACCTCTTCTACATCATCTCCTGCACCTGTACAGCCATCTTATACTGCATGGGTAGGTTCTTGTACAGCTAATGGAACAGATGTATTCTCAGGCGCTACAGGAGCTTCTAAGTTAAGTACATATCCTAAACTTAATGCAGGTAATCTTGTGGATATCATCGGTGAATCTGGTACAAGATATCAGGTTCGTATCGCTGCAAAATATATAGGGTATGTAGAAAAATCTAACATTAAAAATCCTAATACTCCTGCTGCAACAACTACAAAAAAATATCCATTTGTAGGAAAAGTAACTGCAAGTAAATTGAATGTTCGCAAAAAACCCGGTACTGAACATCCATTACTTCCAGAGTATCCGATGTTAAATAAAGACAATCTTGTTAATGTCCTCGGAGTTACAAAAGATACTAAAGGTGACAGATGGTACAAAGTATCAATCACTAAAAAAGAATATGTTGGCTATGTATCAGCCAAATATATCATTAAGGCATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2BOY) rather than this protein.
PDB ID
2BOY
Method AlphaFoldv2
Resolution 87.70
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50