Protein

Protein accession
A0A8S5VCB0 [UniProt]
Representative
OqMD
Source
UniProt (cluster: phalp2_28277)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MLRGIDVSGYQALSATYSHPNVETAYSGSDFVIAKATQGTQPMNRYMTAQLQRALADGKLIGVYHYAEGGSPVAEADAFVACVSGYIGKALLCLDWENGDNDAWGSTVWARQFVDRVYAKTGIYPVVYTYPAGRPQVASCADVSRLWIAGYPDNRFSWNLPEMIYNTGTWSDWTIWQYSSAGGTVDLDVAKLTYAEWEQLAQGESKFEPHWVKNSTGWWYATSPSAYYYSQWAFINGSWYYFDARGYAVTGWYFDGADWFYLCPEEGPQECAMLTGMQHIGSYDYYFANDGRMATGIFDAEGKKYLASENGNLLSAGVHVHNDHAYAVNADGSVQADSTVQVDTDEAGRLTSLH
Physico‐chemical
properties
protein length:354 AA
molecular weight:39333,9 Da
isoelectric point:4,61
hydropathy:-0,31
Representative Protein Details
Accession
OqMD
Protein name
OqMD
Sequence length
161 AA
Molecular weight
18033,40700 Da
Isoelectric point
4,52605
Sequence
SERGEQLAQGESKFEPHWVKNSTGWWYATSPSTYYYSQWAFINGSWYYFDARGYAVTGWYFDGSDWFYLCPEEGPLECAMLTGMQHIGSCDYYFASDGRMATGIFDAEGKKYLASENGNLLPAGVHVHNDHAYAVNADGSVQADSTVQVDTDDVGRLTSLH
Other Proteins in cluster: phalp2_28277
Total (incl. this protein): 47 Avg length: 190,6 Avg pI: 4,96
Protein ID Length (AA) pI
OqMD 161 4,52605
11x52 298 4,91972
3Yx 104 5,05631
61cBc 104 6,07213
627oU 292 4,58306
6YvRF 209 4,59432
6ZKJR 189 7,08131
6ZfwR 216 4,93422
6aVR1 192 5,18584
6cMra 218 4,47695
6tyT1 297 4,69276
73LXk 104 4,87101
73a4i 104 5,29151
73ji2 104 4,83236
73jkj 104 5,03096
73mZM 104 5,03096
73r5I 104 4,84435
7447R 104 5,05631
748RV 104 5,03096
7NJl9 297 4,51577
7Nafz 180 4,75006
7OVy7 202 7,79205
7QDgP 147 5,33698
7ReKW 147 5,33698
7gLMF 104 5,08052
7keB9 104 4,83236
7keHD 104 5,00447
7keJw 104 5,03096
7l8IN 104 4,83236
7ljT1 108 4,88107
7mpaA 198 5,51318
88Gyv 288 4,59045
8I1xc 147 5,34090
8I1xd 171 5,03130
8n07Z 192 4,34985
BIcE 211 4,33479
CUfP 288 4,73301
HnuQ 288 4,54350
Hzor 148 4,92722
NrZE 288 4,59165
OTq9 130 4,22947
OqAN 288 4,48439
z76c 211 4,66378
A0A8S5QBW4 335 4,63814
A0A8S5ST48 354 4,50349
A0A8S5U8B5 354 4,49155
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32236
7mjU4
 1 31,4% 140 5.796E-31
2 phalp2_21401
41mlU
 1 37,2% 118 2.547E-23
3 phalp2_31217
7Ys8w
 6 25,8% 120 1.223E-22

Domains

Domains [InterPro]
Choline_bind_3
Representative sequence (used for alignment): OqMD (161 AA)
Member sequence: A0A8S5VCB0 (354 AA)
1 161 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF19127

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctYkG6
[NCBI] 		2825551 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK016242 [NCBI]
CDS location
range 26836 -> 27900
strand +
CDS
ATGCTTAGGGGCATTGATGTAAGCGGTTATCAGGCATTGAGTGCGACATACTCGCACCCAAATGTCGAGACTGCATACAGTGGCTCTGATTTTGTGATTGCTAAGGCTACCCAGGGCACACAACCAATGAACCGCTACATGACCGCACAGCTTCAACGTGCACTGGCTGATGGCAAGCTCATTGGTGTGTACCATTACGCTGAAGGTGGCTCACCTGTCGCGGAAGCTGACGCATTTGTTGCGTGTGTCTCTGGCTACATTGGTAAGGCTCTCTTGTGCTTAGACTGGGAAAACGGTGATAATGACGCATGGGGCTCAACAGTATGGGCAAGGCAGTTTGTTGACCGTGTCTACGCTAAAACAGGCATCTATCCTGTTGTGTACACGTATCCCGCTGGACGTCCCCAGGTTGCGTCTTGCGCTGATGTGTCGCGTCTGTGGATTGCAGGATACCCAGACAATCGCTTCTCTTGGAACTTGCCTGAGATGATCTATAACACTGGCACATGGAGCGATTGGACCATCTGGCAGTATTCAAGCGCAGGCGGTACCGTTGACCTCGATGTGGCAAAACTGACCTATGCAGAGTGGGAGCAGCTCGCACAAGGTGAGTCTAAGTTCGAGCCACATTGGGTCAAGAACTCCACAGGCTGGTGGTATGCGACAAGTCCAAGTGCTTACTACTACAGTCAGTGGGCATTCATCAATGGTTCTTGGTACTACTTTGACGCACGTGGATATGCAGTCACAGGTTGGTACTTTGATGGCGCAGACTGGTTCTATCTTTGCCCAGAAGAAGGACCTCAAGAGTGTGCCATGCTGACAGGTATGCAGCATATTGGAAGCTATGACTACTACTTTGCCAATGACGGTCGCATGGCAACAGGTATCTTCGATGCAGAAGGTAAGAAGTACCTTGCTTCTGAAAATGGCAATCTTCTTTCTGCTGGCGTTCACGTTCACAATGACCACGCTTATGCAGTCAACGCTGATGGTTCTGTACAGGCTGACAGCACAGTGCAAGTAGACACAGATGAAGCTGGTCGATTGACTTCATTGCACTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (OqMD) rather than this protein.
PDB ID
OqMD
Method AlphaFoldv2
Resolution 92.87
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50