Protein

Protein accession
A0A8S5UJ60 [UniProt]
Representative
3vPEm
Source
UniProt (cluster: phalp2_36642)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKGIDISRHNTIRNFPAIKSQGVDFCVIRAGYGTVIDAKFEAHIKAAKDCGMLVGVYWFCYALDVADARREAEVCAEALRGHQLDLPVFYDFEYDTERYAKTHKVVYSPKLRTDIIETFCNEIIKRGYKAGVYTNPDYWLYRLNADRLSKYSLWIASYKSKDGKATFDTVLPTDLLPAFSNAMIWQFGMCKMPKAVGYVDIDYGYGINPPAPKKTYKVGDLYTIKPGDLYTTGRKVPARLVGKTYTIRQTKPGAVLLEEIVSWVEV
Physico‐chemical
properties
protein length:266 AA
molecular weight:30199,5 Da
isoelectric point:8,92
hydropathy:-0,21
Representative Protein Details
Accession
3vPEm
Protein name
3vPEm
Sequence length
179 AA
Molecular weight
20444,25890 Da
Isoelectric point
9,36592
Sequence
VFYDFEYDTERYATKHKVTYNPKLRTDIIETFCTEMTKRGYKAGVYTNPDYWLYKLNADRLSKHSLWIASYKSKDGKATFDTVLPTDLPPAFSNAMLWQFGMCKMPKAVGYVDVDYGYGVKPPAPKKTYKVGDEYTIKPGDLYTTGRKVPARLVGKTYTVRQVRSGAVLLAEINSWVAV
Other Proteins in cluster: phalp2_36642
Total (incl. this protein): 2 Avg length: 222,5 Avg pI: 9,14
Protein ID Length (AA) pI
3vPEm 179 9,36592
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_4531
3PYph
 1 28,8% 118 5.460E-08

Domains

Domains [InterPro]
GH25
Unannotated
Representative sequence (used for alignment): 3vPEm (179 AA)
Member sequence: A0A8S5UJ60 (266 AA)
1 179 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctTDf8
[NCBI] 		2825517 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK016093 [NCBI]
CDS location
range 3245 -> 4045
strand +
CDS
ATGAAAGGCATCGATATCTCCCGGCACAACACGATCCGGAACTTCCCCGCGATAAAATCACAGGGTGTGGATTTCTGCGTCATCCGCGCCGGGTACGGAACGGTCATCGACGCGAAATTTGAAGCCCACATCAAAGCGGCGAAAGACTGCGGAATGTTGGTCGGTGTGTACTGGTTTTGCTACGCGCTCGACGTCGCCGACGCGCGGCGGGAAGCCGAGGTGTGCGCGGAGGCACTGCGCGGGCATCAGCTCGATTTGCCGGTGTTTTATGACTTTGAGTACGACACAGAGCGGTACGCCAAAACGCACAAGGTGGTCTATAGCCCGAAGCTCCGGACGGACATCATCGAAACATTTTGTAACGAAATCATAAAGCGCGGCTATAAAGCCGGAGTTTACACGAATCCGGACTACTGGCTCTACCGGCTCAACGCCGACCGGCTGTCGAAGTACTCACTGTGGATCGCCTCGTACAAAAGCAAGGACGGCAAAGCGACTTTCGACACTGTGCTTCCGACCGATCTTCTGCCGGCGTTCTCGAACGCTATGATCTGGCAGTTCGGTATGTGCAAAATGCCGAAAGCCGTCGGGTATGTGGACATCGACTACGGCTACGGAATAAACCCACCTGCGCCGAAGAAAACGTATAAGGTCGGCGACCTTTACACGATAAAGCCCGGCGACCTTTACACGACCGGACGGAAAGTTCCGGCACGGCTCGTCGGCAAGACCTACACCATCCGACAGACGAAACCCGGCGCGGTGTTGCTGGAAGAGATTGTGAGCTGGGTTGAAGTATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3vPEm) rather than this protein.
PDB ID
3vPEm
Method AlphaFoldv2
Resolution 94.50
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50