Protein

Protein accession
A0A8S5TN99 [UniProt]
Representative
6aXOr
Source
UniProt (cluster: phalp2_24702)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTLKVVDLSNNNGSKNINDYPADAYMFKATEGCNFVDRYCDPFVQQAIKSGKLFGVYHFIDGSNWQTQTDFFIKNVQGYIGKGILVLDYEMYGRQGTGILKQMLDRIQQKTGIKALVYTSASVLFEEDFSAIVKADYGLWVAAYQSNFPKIKHWSNAAMWQYTSTPYDQNIFYGDQNTWKAYATSGKCQTSSDQVKVESVQVQQSKPQTPSDHDKAVAASKVVHQGNAYGKLERFKFVGNSKVNIASWLVPDKPEGPIGKFAYILIMEHGTTKEITRVASQGIKRPDVKKNYGYKGGDALGMDVTVDLSWVKKGTKIDVILRRCNQANGEGAVNDVHIKDIYLTL
Physico‐chemical
properties
protein length:345 AA
molecular weight:38637,4 Da
isoelectric point:8,94
hydropathy:-0,41
Representative Protein Details
Accession
6aXOr
Protein name
6aXOr
Sequence length
347 AA
Molecular weight
38797,63030 Da
Isoelectric point
8,97279
Sequence
MTLNVVDLSNNNGSKNIADYPADAYMFKATEGTGFVDKYCDPFVQQAIKAGKPFGVYHFINGEDWRAQTDFFLNNVRGYVGKGILVLDYEMYGRQGTGILKQMLDRIQQKTGIKALVYTSASVLFEEDFSEIVKADYGLWVAAYQSKFPALKYWSNAVMWQYTSIPYDKNYFYGDKNTWKAYATAGIGKDNESADSISQIPTPNKHDNIIAQSPIKKSGNYIAKLEVFNELKWGIFRIAGWLVPINGAPALNYGFVFWKEAGTGEEIGRCPSKGIVRNDVNKAYGLPNGSKFGLDGTLDIKKFAGKKVYPCLRRTNDKAGNSIAGKPNGNGWIDIEFPEYVLTIPKR
Other Proteins in cluster: phalp2_24702
Total (incl. this protein): 10 Avg length: 343,0 Avg pI: 8,82
Protein ID Length (AA) pI
6aXOr 347 8,97279
1bJum 345 9,07549
60dv1 343 9,20230
6co7R 343 8,78577
74AYK 329 8,13728
76hx9 345 8,93836
7QzXr 345 9,02997
7muHc 345 8,73993
7muJd 343 8,41630
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_39916
1kJlV
 4 49,1% 248 9.719E-74
2 phalp2_12276
79roT
 46 38,2% 251 1.677E-43
3 phalp2_24845
7umqo
 6 29,8% 275 4.982E-23
4 phalp2_29179
7C4V5
 4 32,0% 256 2.976E-22
5 phalp2_36209
7jVrq
 19 26,6% 263 9.651E-09
6 phalp2_15880
4Ajn2
 3 26,2% 259 2.896E-07
7 phalp2_6287
6QxUm
 6 24,1% 269 8.973E-07
8 phalp2_30679
6VfCQ
 1 21,6% 277 1.999E-05
9 phalp2_12499
TuOL
 20 25,5% 274 3.512E-05

Domains

Domains [InterPro]
GH25
Unannotated
Representative sequence (used for alignment): 6aXOr (347 AA)
Member sequence: A0A8S5TN99 (345 AA)
1 347 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctamP19
[NCBI] 		2827896 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032864 [NCBI]
CDS location
range 14930 -> 15967
strand +
CDS
ATGACATTAAAGGTAGTAGATTTATCCAATAATAACGGTTCAAAAAATATCAATGACTATCCAGCAGACGCTTACATGTTTAAAGCAACGGAAGGTTGTAACTTTGTAGATCGCTATTGTGATCCGTTTGTTCAGCAAGCAATCAAGTCTGGAAAACTTTTTGGTGTCTATCATTTTATTGACGGTTCAAATTGGCAAACGCAAACAGATTTCTTTATTAAAAATGTTCAAGGATATATTGGTAAAGGGATTTTAGTTCTAGATTATGAAATGTATGGACGTCAAGGAACAGGTATTTTAAAACAAATGTTAGATCGCATCCAACAAAAAACAGGTATCAAAGCGTTAGTTTATACGTCCGCTTCTGTTTTATTTGAAGAAGATTTCTCAGCGATTGTTAAAGCTGATTATGGGTTATGGGTAGCAGCTTATCAATCTAATTTCCCTAAAATTAAACACTGGTCAAATGCAGCTATGTGGCAATATACTTCGACACCATACGATCAAAATATCTTTTATGGTGATCAAAATACTTGGAAAGCCTATGCCACATCTGGTAAGTGTCAAACTTCAAGTGATCAAGTGAAAGTAGAATCTGTACAAGTACAGCAATCAAAACCACAAACCCCATCCGACCATGATAAAGCAGTAGCAGCAAGTAAAGTTGTTCATCAAGGGAACGCATATGGAAAACTGGAACGATTCAAATTTGTAGGAAATAGCAAAGTGAATATAGCTAGTTGGCTGGTGCCAGACAAACCAGAAGGACCAATTGGTAAATTTGCTTATATTCTTATCATGGAACACGGCACTACAAAAGAAATCACTCGTGTGGCTTCGCAAGGTATCAAACGTCCTGACGTGAAGAAAAACTATGGCTACAAAGGTGGCGATGCATTAGGAATGGATGTCACAGTGGATTTAAGCTGGGTGAAAAAAGGCACGAAAATCGATGTCATTTTGCGCCGTTGTAATCAAGCGAACGGCGAAGGTGCGGTTAATGATGTGCATATTAAGGATATCTATTTGACGTTATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6aXOr) rather than this protein.
PDB ID
6aXOr
Method AlphaFoldv2
Resolution 89.72
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50