Protein

Protein accession
A0A8S5SX96 [UniProt]
Representative
3mo9t
Source
UniProt (cluster: phalp2_22968)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNKKFRGIDISLYQRNIDYDRVIKDNDFVIIKAGQGRTAEYNFPFTDPLFEQHIKAFRSRISGKKFYIGVYWYFMGRTEAETLEEVKYLIQILKPYKENIDIGVALDVEDTSLMGDVDGLSRRVNLFLNSIIGAGYKAYIYANEYFLATQFKNNLNFPLWLASIDDGTKSHKGLQKKYPNLKIWQYSFKGTEGGIYPVDCNEAVDIIGDTNTDYLVNMKDVVTLTRFLSGWNIKVNEVQSDINQDGYVNMKDLIELIRLMVEE
Physico‐chemical
properties
protein length:263 AA
molecular weight:30469,4 Da
isoelectric point:5,42
hydropathy:-0,31
Representative Protein Details
Accession
3mo9t
Protein name
3mo9t
Sequence length
254 AA
Molecular weight
28099,61940 Da
Isoelectric point
6,16563
Sequence
MAKNKIYKGIDISLFQPGADFPAIKAAGIDFVMLKAGQGRIPGEWNAPFTDPYFERYIKAADAAGLYAGSYWYFMANTEAQVREEAAYYIALLRKYKFNHQLWAAVDVEDSHLTGDRAALTARVKLFCDLVRAAGFRPMVYANSWWLESRFESPAGVPIWEANWSASARPSRARMWQYTSTGRVGGINGNVDMNVAYSIIGDADGDGNVDMADVIRMMRAAAGWKVGIDEGQADLDKDGKVSVKDVILLTRALS
Other Proteins in cluster: phalp2_22968
Total (incl. this protein): 23 Avg length: 258,9 Avg pI: 5,82
Protein ID Length (AA) pI
3mo9t 254 6,16563
3ZT67 258 9,04364
3tq5A 259 5,61572
3trLJ 263 5,42468
3y2Bx 263 5,42468
4Milc 262 9,23763
5PfL3 263 5,17158
5RBGi 263 5,42468
5ZhLn 263 5,28417
5xS6 258 6,30733
60ekL 263 5,42468
61DOf 263 5,28417
6aErH 263 5,61338
6cMEI 263 5,42468
6cdIK 263 5,41541
6dVW5 263 5,28417
6teTA 263 5,42468
6wLyM 263 5,42468
7Ujek 254 5,78970
8bLy0 263 5,61338
8nXzy 263 5,42468
8r0dw 202 5,13383
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24174
2ojoF
 57 38,7% 214 5.580E-50
2 phalp2_24035
8aWkT
 56 35,5% 211 4.500E-40
3 phalp2_3425
3TK4D
 923 37,4% 195 1.228E-37
4 phalp2_33310
6kV0o
 68 39,1% 202 1.085E-36
5 phalp2_13529
7Jyqc
 660 34,4% 209 2.146E-34
6 phalp2_38474
1kWHZ
 2 35,3% 201 5.449E-34
7 phalp2_26548
858CP
 728 35,3% 195 2.575E-33
8 phalp2_6199
5X5xO
 102 35,2% 204 3.512E-33
9 phalp2_34702
2Vinc
 3 36,6% 199 8.912E-33
10 phalp2_27173
3dR30
 17 32,3% 198 7.817E-32

Domains

Domains [InterPro]
GH25
Representative sequence (used for alignment): 3mo9t (254 AA)
Member sequence: A0A8S5SX96 (263 AA)
1 254 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183|PF00404

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctUm43
[NCBI] 		2827738 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032689 [NCBI]
CDS location
range 12358 -> 13149
strand -
CDS
ATGAATAAAAAATTTCGTGGTATAGACATTTCGCTTTATCAGCGGAACATTGACTATGATAGAGTTATAAAAGATAATGATTTTGTAATAATCAAAGCGGGGCAGGGAAGAACAGCGGAATATAATTTCCCGTTTACTGACCCACTTTTTGAACAGCATATAAAGGCGTTTCGTTCACGCATATCGGGGAAGAAATTCTACATAGGAGTTTATTGGTACTTCATGGGTAGAACGGAAGCCGAGACTCTTGAAGAAGTTAAGTATCTTATACAGATACTTAAACCTTACAAAGAAAATATAGATATTGGAGTGGCTCTCGATGTAGAAGATACATCCCTCATGGGAGATGTTGACGGTCTGTCTCGTAGAGTGAATCTTTTCCTCAATTCTATAATTGGAGCAGGATACAAGGCGTATATTTATGCTAACGAATATTTTCTCGCTACTCAGTTTAAGAATAATCTGAATTTCCCGCTTTGGCTCGCGTCTATAGACGACGGCACTAAGTCGCACAAGGGACTTCAGAAGAAATATCCCAACCTTAAAATATGGCAGTATAGCTTTAAGGGTACAGAGGGCGGAATATACCCCGTGGATTGCAACGAAGCGGTTGATATAATCGGAGACACCAACACCGATTACCTCGTAAACATGAAAGATGTTGTTACGCTCACGCGCTTTCTGTCAGGTTGGAATATAAAGGTCAACGAAGTGCAGTCTGACATAAATCAAGACGGATATGTAAACATGAAAGACCTTATAGAACTTATAAGGCTCATGGTAGAGGAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0000272 polysaccharide catabolic process biological process None (UniProt)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3mo9t) rather than this protein.
PDB ID
3mo9t
Method AlphaFoldv2
Resolution 86.43
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50