Protein

Protein accession
A0A8S5RKJ3 [UniProt]
Representative
6mR1S
Source
UniProt (cluster: phalp2_24709)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MLPIMDVSRWQGSIDWDKVKASGLISGVMLRALGNSAEDKPSKPYIDPYFARNYTECQRLGIPCGVYYYCKAVTTAEADAELALLHKVLTGKTLQLPVAVDIEDKYVQAPLDKQTLTDIAAHALGTVERWGFYAMLYTGLYFARDNLYMTGAALRKYDVWLAAYRSKKPEPGWPFGLWQYTSKGKIPGVVDAIPGKSSGVDLSVPYKDYTKIITKKGLDRLREV
Physico‐chemical
properties
protein length:224 AA
molecular weight:25044,7 Da
isoelectric point:8,91
hydropathy:-0,19
Representative Protein Details
Accession
6mR1S
Protein name
6mR1S
Sequence length
112 AA
Molecular weight
12768,75780 Da
Isoelectric point
9,56751
Sequence
MFPIMDVSRWQGNIDWDKVKASGLVSGVMLRALGNSAKDAPSKPYIDPTFERNYRECQRLGIPCGVYYYCKAVNTAEADAELALLRPAKRCSCRWRLTLRIPMCKHRSTSRP
Other Proteins in cluster: phalp2_24709
Total (incl. this protein): 9 Avg length: 149,9 Avg pI: 9,02
Protein ID Length (AA) pI
6mR1S 112 9,56751
3s6WG 110 6,24532
3sC7b 149 8,17261
3ynP9 106 10,75076
6pusf 86 9,47887
8tQNs 118 9,72739
A0A8S5MQG5 226 9,09663
A0A8S5S531 218 9,25710
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13680
63gYT
 2 46,1% 78 3.231E-16
2 phalp2_25924
66tGM
 6 42,1% 76 4.046E-15
3 phalp2_31214
88VlE
 13 43,5% 78 7.610E-15
4 phalp2_3380
3qQTc
 8 44,7% 76 1.305E-13
5 phalp2_27642
6tvgH
 33 44,9% 89 1.790E-13
6 phalp2_19101
1qxtp
 5 39,4% 76 2.790E-11
7 phalp2_26543
8b1WD
 4 36,9% 73 3.825E-11
8 phalp2_6600
1kY8f
 1 44,2% 70 5.243E-11
9 phalp2_34287
3mtX2
 6 40,7% 76 7.186E-11
10 phalp2_15198
D6Gl
 21 39,4% 76 3.476E-10

Domains

Domains [InterPro]
Unannotated
Disordered region
Representative sequence (used for alignment): 6mR1S (112 AA)
Member sequence: A0A8S5RKJ3 (224 AA)
1 112 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage virus sp. ct6GG30
[NCBI] 		2825804 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK059113 [NCBI]
CDS location
range 9157 -> 9831
strand -
CDS
ATGCTCCCCATTATGGACGTATCCCGCTGGCAAGGCAGCATCGACTGGGACAAGGTCAAGGCAAGCGGCCTTATCTCCGGCGTGATGCTGCGGGCGCTGGGCAACAGTGCGGAAGACAAGCCAAGCAAGCCGTACATTGATCCCTATTTCGCCCGCAACTACACCGAGTGCCAGCGGCTGGGCATTCCCTGCGGCGTGTACTACTACTGCAAGGCGGTCACCACGGCAGAGGCTGACGCAGAACTTGCCCTGCTGCACAAGGTGCTGACCGGAAAGACGTTGCAACTGCCGGTGGCGGTGGACATTGAAGACAAGTATGTGCAGGCTCCGTTGGACAAGCAGACCCTGACCGACATTGCAGCCCACGCGCTTGGCACGGTGGAGCGTTGGGGCTTCTACGCCATGCTGTACACCGGGCTGTACTTTGCCCGCGATAACTTGTACATGACCGGTGCGGCGCTGCGCAAGTACGATGTATGGCTGGCAGCCTACCGCAGCAAGAAGCCCGAACCGGGCTGGCCGTTTGGCTTGTGGCAGTACACCAGTAAGGGCAAGATTCCCGGCGTCGTGGACGCGATACCGGGCAAGAGTTCCGGCGTGGACTTGTCTGTGCCTTACAAGGACTACACCAAAATCATCACGAAAAAGGGGCTGGACAGGCTCCGGGAGGTATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6mR1S) rather than this protein.
PDB ID
6mR1S
Method AlphaFoldv2
Resolution 69.74
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50