Protein

Protein accession
A0A8S5QXY8 [UniProt]
Representative
5VoQx
Source
UniProt (cluster: phalp2_224)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNKLFGIDISHWQGDLSIKQARDERGVQFVIVKAAGADAGKYKDSKFEDYYAQCKAIGMPVGAYYYGNAKSVADAQAEADHFLSVIAGKQFEYPIYYDVEGNMLENAKDTLTDIVIAFCDRCEKAGYFVGVYTSDSHFQSHVDDSRLQRFTHWVAKYSSNTPATSHDIWQYGGGQNFIADKTICGRTVDQDFCYRDFPAAIKAAGLNGYTANNDDGKDEPEASAPEGTTLELVYRTMKDEFGGGDARKAALGSRYDEVQEVINHIYSASAQELADEVWTGKYGDDEVRRTFLGDRWQEVQDIVNDGGKKYHTIESGETLTSIAKDFGTTVDALVSLNGIENPNLIITGDSIRVR
Physico‐chemical
properties
protein length:354 AA
molecular weight:39244,8 Da
isoelectric point:4,77
hydropathy:-0,50
Representative Protein Details
Accession
5VoQx
Protein name
5VoQx
Sequence length
177 AA
Molecular weight
19605,54850 Da
Isoelectric point
4,97525
Sequence
LLTRQSAEELWTRIFRYRDFETEIKKAGLNGFSASAGDETKEPEVSEPEGSTLDLLYRTMKDEFGGGDARKAALGSRYNEVQDVINHIDKASVQELVDEVWAGKYGDDEVRRTILGSRWQEVQDAINAGNKKYYTIKSGDTLSGIAAKYGTTVNAIAQLNGIENPNLIIAGDTIRVK
Other Proteins in cluster: phalp2_224
Total (incl. this protein): 6 Avg length: 248,0 Avg pI: 6,31
Protein ID Length (AA) pI
5VoQx 177 4,97525
1nG9q 250 4,52907
3sPq9 208 9,25291
5Ntdu 250 4,88886
6iuDc 249 9,42181
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_40352
3s9tm
 12 75,7% 107 6.017E-47
2 phalp2_38035
63Vjb
 2 39,6% 154 7.881E-28
3 phalp2_17221
3xRQT
 3 35,0% 174 5.985E-20

Domains

Domains [InterPro]
Unannotated
LysM
Representative sequence (used for alignment): 5VoQx (177 AA)
Member sequence: A0A8S5QXY8 (354 AA)
1 177 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctyWv1
[NCBI] 		2826718 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015755 [NCBI]
CDS location
range 14413 -> 15477
strand -
CDS
ATGAACAAACTTTTTGGTATTGATATTTCACATTGGCAGGGAGACCTCAGCATCAAGCAGGCAAGAGATGAAAGAGGGGTGCAGTTCGTAATCGTTAAAGCTGCCGGAGCAGATGCGGGCAAGTACAAGGACAGCAAGTTTGAAGATTATTACGCACAGTGCAAGGCGATTGGTATGCCTGTCGGTGCGTATTATTATGGTAACGCCAAGTCTGTTGCAGACGCACAGGCGGAGGCAGACCATTTCCTGTCAGTAATTGCAGGAAAGCAGTTTGAATATCCTATCTACTACGATGTCGAGGGTAATATGCTCGAGAACGCAAAGGACACTCTCACAGACATCGTTATTGCATTTTGCGACAGATGCGAAAAGGCGGGATACTTCGTTGGAGTTTATACATCAGACTCACACTTCCAGTCTCATGTAGACGACTCTCGTTTGCAGAGATTTACTCATTGGGTGGCAAAGTATTCATCCAACACACCTGCAACATCTCACGATATTTGGCAGTATGGCGGCGGTCAGAATTTCATTGCAGACAAGACAATCTGCGGCAGAACAGTAGACCAAGATTTCTGCTATCGTGATTTCCCTGCGGCAATCAAAGCGGCAGGACTCAATGGATATACTGCCAACAATGATGACGGCAAGGATGAGCCGGAAGCGTCTGCTCCGGAGGGAACAACGCTTGAATTGGTTTACAGAACTATGAAAGATGAGTTCGGCGGCGGAGATGCAAGAAAAGCAGCACTCGGAAGCAGATATGATGAGGTGCAGGAAGTTATCAATCATATTTACAGTGCGTCCGCACAGGAGTTGGCAGATGAAGTATGGACTGGCAAGTATGGAGATGATGAAGTAAGGAGAACTTTTCTCGGAGACAGATGGCAGGAAGTACAGGACATCGTAAATGATGGCGGCAAGAAGTACCATACTATCGAGAGCGGAGAAACGCTCACAAGCATTGCGAAGGATTTCGGAACAACTGTCGATGCTCTCGTTTCTCTGAACGGCATTGAGAACCCGAACCTCATCATTACAGGAGACTCCATTAGAGTCAGATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5VoQx) rather than this protein.
PDB ID
5VoQx
Method AlphaFoldv2
Resolution 83.54
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50