Protein

Protein accession
A0A8S5QXB0 [UniProt]
Representative
1nmLt
Source
UniProt (cluster: phalp2_8516)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKKAIDVSKHQGLIDWLKVKNAGISLAMIRSGYGRYTSQRDPQFDRNVRECEANGIAWGTYWYSYATSPAQAQQEARCCLQVIKGLKPTLPVAYDIEYEPGILALSNATRTEMVRAFLEEIEAAGYYGILYASKDFIQNRLNYKELTAYDVWCAQYGSACTCPLPYGMWQYSSKNPLGIPGFGNSLDCNNVYKDYPSIIQNAELNGWIEPEDDGGSDDSARLQRITIGPISSGDVATLRKLCESLSLTSMGLYKESSGVLTIGPVSSGDAWAIMRQCEALELTDMGLYHSEYVD
Physico‐chemical
properties
protein length:294 AA
molecular weight:32658,5 Da
isoelectric point:4,90
hydropathy:-0,29
Representative Protein Details
Accession
1nmLt
Protein name
1nmLt
Sequence length
512 AA
Molecular weight
57761,83650 Da
Isoelectric point
8,72755
Sequence
WLGYSELGIQNRNSRLRRFRGSPQQHAALFIGMDMEEDKIRRIKMRLKNEEALLHWPLAQHIITAGWLYNDGSLHRALDFRAAVGTPVYAAEAGTVAIAYHWNGKRTSGDTNSYGNMVKLKHATYKYGTLETLYAHLNKIVVKQGQQVQEGQLIGYSGDTGNCYGAHLHFEVRWKGQRTNPLNWLDADFSTASSAVKLGSYSSIQHTEEVKRMYYAIDVSKHQNKFDWQAAYSKGIRHAMLRAGYGRYSSQVDPQFERNAAECARLGIQYGVYWYSYASTPEEARQEARCCLAAIKDKHLCLPVAYDIEYEPCILRLTNAQRTALVHAFLSEIEAAGYYGILYASCGFIRNRLDYKALSKYDIWVAQYGSTCTCPLPYGIWQYSSRNALGVPGYGTSLDCNRVYKDYEQLMIQACLQGHTAPTPEDTTPNKLDKQRITIGRISSGDRATIRALCEGLGLIAAGLYRETCADGNQWMLDVGPVSSGDAWYIMRKCTELELVKAGLYKSEYVKG
Other Proteins in cluster: phalp2_8516
Total (incl. this protein): 187 Avg length: 468,7 Avg pI: 7,90
Protein ID Length (AA) pI
1nmLt 512 8,72755
1FDCM 532 6,71936
1m7lQ 480 7,84324
1mfRK 470 6,59920
1mp8K 480 7,50470
1n7Ij 480 8,22096
1n9mi 468 6,73090
1nc3T 480 8,48850
1ncOo 468 7,19942
1nkCG 457 9,25303
1ochV 469 8,67172
2lYi1 468 8,08151
2lZOb 469 8,10356
2lZSr 469 7,16139
2m9x8 467 6,88044
3GCdO 469 6,85395
3kyUS 469 8,47368
3l0rp 468 8,36737
3l3mE 468 8,57109
3lJOs 469 7,82093
3lV9l 469 8,54743
3lWGN 469 8,34467
3lgQJ 468 8,81800
3m0gu 469 8,27595
3m1vV 469 7,82454
3m26t 468 8,05676
3m6g6 468 8,62995
3miOa 470 7,48293
3mmI2 469 8,06127
3mp2v 469 8,65754
3mqrr 457 9,33659
3piG0 469 7,13815
3qKkM 469 8,09086
3rQzX 468 8,23244
3sR7r 461 8,89188
3slJa 468 7,52965
3tOcK 468 7,16549
3tYKH 468 7,49521
3uBE4 468 7,52670
3uJx2 469 8,10356
3uQkc 469 8,08093
3uXrc 469 8,08558
3uxqA 469 8,25803
3vGTh 468 6,50377
3vGfH 482 8,58353
3vOLi 462 8,65780
3vuD2 468 8,26177
3vvbJ 468 8,10066
3w95l 469 7,18356
3whSR 468 7,55552
3wnRL 469 8,60422
3xIqn 468 7,51658
3xY16 469 6,85492
3xYWq 468 7,18152
3xZXt 373 8,37684
3xrnV 468 6,87777
3xtiy 469 7,83950
3xwx5 469 7,16770
3yFUc 469 8,07926
3yOvI 469 8,09260
3yaj8 468 7,51937
3yq7u 469 6,88158
4Vw5u 467 7,84105
4z8i6 480 8,24688
5Kj4U 480 8,45137
5KzUe 467 7,84324
5LX4M 469 7,15946
5Llpl 467 8,08545
5LuWH 468 8,08467
5MlZW 481 8,26622
5MzJw 468 7,50396
5Mzrr 457 9,19559
5N49D 467 7,14167
5NAqK 372 7,10387
5NMc0 457 9,05009
5Nm4R 479 8,38490
5NpRe 479 7,16242
5O1KN 467 8,25983
5OYAB 469 7,13917
5PgGh 467 6,50684
5UM78 468 6,85174
5V3WM 468 7,84704
5VB0k 481 8,07468
5VGVJ 480 8,38529
5VVaN 480 8,07230
5XWFf 467 7,50760
5Yw20 468 8,59236
5YxFC 457 9,29255
5Z7rm 457 9,05009
5Zsdi 479 8,35879
60yfW 480 7,83763
61Qav 479 8,69957
61f4Z 481 8,23160
62bdu 467 8,23405
62j8y 480 8,07687
63Ekl 481 8,25281
63MAk 468 8,38819
64RO0 481 8,26622
64aGf 457 9,25291
67QJx 480 7,16628
67dTQ 472 7,50385
67suY 480 7,51641
67u3Z 467 7,54114
68ens 470 7,49538
6YCbe 468 8,81800
6Zkyp 481 8,07230
6a5b8 480 9,13770
6aQpw 480 8,56535
6aXCQ 480 7,52488
6b94S 480 8,25113
6bQR4 468 6,88016
6csmG 457 9,37830
6ct6H 479 7,51562
6dEoF 429 5,92867
6dGSM 467 8,30258
6e1ug 481 7,84343
6e76I 480 7,84511
6fBPF 457 8,98497
6fUS1 480 7,14139
6fqKq 480 8,09583
6iGqa 479 8,36150
6if0a 480 6,85822
6itXw 481 8,07230
6jRgb 469 6,82076
6jTXi 457 9,05009
6k561 468 8,36414
6k8bF 467 7,84672
6kZr2 467 8,66444
6kz50 468 7,85820
6lu30 467 7,85091
6mRFY 468 7,84898
6nQ17 457 9,29997
6nuPc 480 9,00754
6nzlO 468 7,48555
6pxwF 478 8,38987
6rEwO 479 7,85072
6sWNF 480 8,66515
6sjPy 467 8,08777
6tBSa 480 8,22824
6uJEY 478 8,69957
6uTy2 467 7,14093
6uyr7 478 7,86348
6vgpS 457 9,14176
6vnbY 467 8,64091
6w0rf 469 6,85020
6wMUS 469 7,14116
6wnnu 468 7,86774
701Ga 481 7,49379
70JuX 480 8,25036
71cdf 467 8,08384
7NWGv 469 7,49521
7Wj28 468 7,51709
7X9kJ 469 6,85549
7Y4MD 472 6,69952
7Y8OS 468 8,23405
7YCav 468 8,27795
7ZDwH 468 7,84917
84pUE 468 7,51976
85xpV 468 7,86284
87hsp 468 7,16549
8cECc 468 8,38490
8dlha 468 6,88317
8eLsR 469 8,49798
8fIYF 468 6,85293
8hPPU 469 7,86206
8iKDm 468 6,73090
8jDrc 461 8,84585
8kY8x 468 7,84872
8lZ2H 469 8,58566
8mMdV 469 7,49498
8oCcf 469 8,57128
8r7iy 468 8,08164
8rIwI 468 8,92276
8rKWL 468 6,64069
8shE2 469 7,84485
8tSNZ 469 6,46557
8vR2T 468 7,11911
BKOT 480 8,35879
EBtp 468 7,52704
NBdP 469 6,70100
NGxv 481 8,07687
Ndp0 469 8,80620
Oty7 457 9,15762
qmhV 468 6,93194
xCEL 479 8,07848
zl1Y 467 6,70003
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24298
3nxgr
 64 87,2% 336 4.561E-204
2 phalp2_16387
5Mpkv
 240 33,3% 345 4.853E-55

Domains

Domains [InterPro]
Disordered region
PET_M23
GH25
Unannotated
Representative sequence (used for alignment): 1nmLt (512 AA)
Member sequence: A0A8S5QXB0 (294 AA)
1 512 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctool15
[NCBI] 		2826696 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015762 [NCBI]
CDS location
range 3724 -> 4608
strand -
CDS
ATGAAAAAAGCAATCGACGTAAGCAAGCACCAGGGCTTGATCGACTGGCTCAAAGTCAAAAATGCCGGCATCTCGCTGGCCATGATCCGTTCCGGCTATGGCCGGTATACCAGCCAGCGCGACCCCCAGTTTGACCGCAATGTGCGCGAGTGCGAGGCCAACGGCATCGCCTGGGGTACATACTGGTACAGCTACGCTACCAGCCCTGCCCAGGCGCAGCAGGAAGCGCGCTGCTGCCTGCAGGTGATCAAAGGTCTCAAACCAACGCTTCCGGTGGCCTATGATATCGAGTACGAGCCTGGCATCCTGGCACTGTCCAATGCCACCCGCACCGAGATGGTGCGGGCCTTCCTGGAGGAAATCGAGGCCGCGGGATACTACGGTATCCTGTACGCCAGCAAGGACTTCATCCAGAATAGGCTGAATTATAAAGAGTTGACCGCTTACGATGTCTGGTGCGCACAGTACGGCAGTGCATGCACCTGCCCGCTGCCGTATGGTATGTGGCAGTACAGCTCCAAAAACCCGCTGGGTATCCCCGGATTTGGCAACAGCCTGGACTGCAACAACGTCTACAAGGACTATCCCTCGATCATCCAGAATGCCGAGCTCAATGGCTGGATCGAGCCGGAGGATGATGGCGGCAGCGATGACAGCGCCAGGCTGCAGCGGATCACCATCGGCCCGATCAGCTCTGGCGACGTGGCCACGCTGCGCAAGCTGTGCGAGAGCCTGTCACTTACCAGCATGGGCCTGTACAAGGAGAGCTCCGGCGTGCTGACCATCGGGCCTGTGTCCAGCGGCGACGCCTGGGCGATCATGCGTCAGTGCGAGGCGCTGGAACTGACCGACATGGGCCTGTACCACAGCGAGTACGTGGACTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1nmLt) rather than this protein.
PDB ID
1nmLt
Method AlphaFoldv2
Resolution 81.47
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50