Protein

Protein accession
A0A8S5QJF4 [UniProt]
Representative
1Gg1E
Source
UniProt (cluster: phalp2_16849)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNLIQLYQKQSTWYTGTTTGVPVGICLHDTGCNNKTLKRYVQPNDNDPNWQQLIDLIGWNKNYNDWNHAKRAAGVNAWIGTLADGSVATVQAGPWNYRPWGVGGGRYGSLNGDKNDPNAKFWLQFEICEDSRKDYSYFEKAYFEAVDLCAYWCEMFGFDPHGTVTYKGHQVPVICCHQDSYRLGFGANHSDVYDWFNVFSITMDDFRDAVARKMGQVIVDKPDIPEPDPTPKPTPTPVNDEVKVGSLVSINPGATYYSGTAIPAWVAKRNWYVYSAPEGKDRIVLNNSEDGKYKIMSPINRKDVTVVGATMTPSTPSTPAAPTGYRVKVLTDALNIRKGPGTNYQIAGVIRDRGIYTIVQTQGTWGKLKSGAGWISLGWCSKI
Physico‐chemical
properties
protein length:383 AA
molecular weight:42667,6 Da
isoelectric point:8,27
hydropathy:-0,47
Representative Protein Details
Accession
1Gg1E
Protein name
1Gg1E
Sequence length
940 AA
Molecular weight
104532,10120 Da
Isoelectric point
5,52034
Sequence
MAFTASKLLEIAIAELGYKEKASNFQLDDKEANAGSGNWTKYARDLHTAGYYQAAKNGYAWCDMFVDWCFLQLGGSKEKGEWLECQTGLYGAGCEWSSNCYRWADRCGTEPKVGAQIFFAKNGKGSEEHTGIVEKFDSNYVYTIEGNASNMVKRKTYARNSDYILCYGYPRFDETTNETQATTSTIAADHFDKGDVVKIVSGANWLSGSAVPTWVIKKEWIIKEVSTSDGRVVVNESVDGANKINSPIHYSSLVLVKAANPKEDKVETELDGGNKETEVAQSSLKYSTANPPLVCMQTQSTCYKGTTEMTVLGVLWHSTGANNKTIKRYVQPSDNDPNKDALLKLIGKNQYNNDWNHIDRQAGLNAWIGTLADGTVTTVQTMPWNFRPWGCGSGKNGSCNSGWIQFEICEDNLQDADYFNKAYTEACELTAYLCKMFNLDPHGTINYNGVKVPVILCHADSYDLGFGSNHGDIDHWFPKHGKSMVTVRNDVAKLLQNSTQAAPVEGVYQKGVATQLSKNFKSTEFDCHGDGCCTTTEVDPKLVTYLQTIRDHFGKAVNISSGYRCATHNKSVGGAVGSRHTKGQAADIYINGVTPLEIARYAEQLGILGIGLYETDEDGHFVHVDTRATKSFWYGQAQAKRDTFQEPVKIDISKVNTAKADPKHVWDFLKAKALNDFAVAGLMGNLLAESNMLPINLQNTYEKKLGMTDAEYTAAVDQGIYKDFVKDSAGYGLAQWTYYSRKEDLLEYATSQKKSIGDLDMQLEFLWTELQRYKAVMKQLNEATSVREASDVILHDYEAPADQSEAVEIKRAEFGQKYFDDYAVCMHKSTEIQNQKDATCTEAGYTGDKVCSECNFVVEVGSLIPPIQHNYSLTGKLEPTIETEGYTGDQVCSRCNHTIKGEAIKKLSPIVVTPEDDEVKITIKKSWIQKLIEWLLSLLK
Other Proteins in cluster: phalp2_16849
Total (incl. this protein): 2 Avg length: 661,5 Avg pI: 6,90
Protein ID Length (AA) pI
1Gg1E 940 5,52034
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12879
2os0g
 1 36,1% 620 4.118E-93

Domains

Domains [InterPro]
CHAP
Unannotated
Ami2
PET_M15
Phage_lys2
Unannotated
Disordered region
Representative sequence (used for alignment): 1Gg1E (940 AA)
Member sequence: A0A8S5QJF4 (383 AA)
1 940 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510, PF05257, PF08291, PF18013

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctCUc43
[NCBI] 		2825379 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015668 [NCBI]
CDS location
range 18994 -> 20145
strand +
CDS
ATGAACTTGATCCAACTGTATCAAAAGCAGTCAACGTGGTATACGGGCACTACCACCGGCGTTCCTGTTGGCATCTGTCTTCATGACACGGGCTGCAATAACAAAACCCTTAAACGGTATGTTCAGCCGAATGACAATGATCCGAATTGGCAGCAGCTGATCGATCTTATCGGCTGGAACAAAAACTATAATGACTGGAACCACGCTAAACGGGCTGCCGGTGTAAATGCTTGGATCGGCACATTGGCTGATGGTTCGGTCGCCACAGTTCAGGCTGGCCCGTGGAATTATCGTCCGTGGGGCGTCGGAGGTGGCAGATACGGGTCTCTTAATGGCGATAAGAACGATCCGAATGCTAAGTTCTGGCTGCAGTTCGAGATCTGCGAAGATTCTCGTAAGGATTATTCCTATTTCGAAAAAGCCTACTTCGAGGCAGTTGATCTCTGTGCGTATTGGTGCGAGATGTTTGGCTTTGATCCGCACGGTACCGTGACCTACAAAGGTCATCAGGTTCCCGTTATCTGTTGCCACCAGGATTCTTATCGTCTTGGTTTCGGCGCCAATCACTCTGACGTCTATGATTGGTTCAACGTCTTTAGCATCACGATGGACGACTTCCGTGATGCCGTGGCACGGAAAATGGGCCAAGTTATAGTCGACAAACCGGATATTCCTGAACCGGATCCTACGCCCAAGCCCACGCCAACTCCGGTTAACGACGAGGTTAAAGTCGGATCTCTTGTCAGCATCAATCCCGGTGCAACATACTATAGCGGTACAGCAATTCCTGCATGGGTTGCTAAGCGCAACTGGTATGTATACTCCGCTCCTGAGGGTAAAGACCGTATTGTTCTTAACAACTCAGAAGACGGTAAGTATAAGATCATGTCGCCGATTAATCGAAAAGACGTCACGGTTGTTGGCGCTACGATGACTCCGTCGACGCCGAGTACGCCCGCCGCGCCCACGGGCTATCGCGTAAAAGTGCTTACAGACGCGCTGAATATACGCAAAGGTCCGGGTACTAACTATCAGATCGCAGGTGTTATACGCGATCGGGGTATCTATACTATCGTACAGACCCAAGGTACCTGGGGCAAGCTTAAGAGCGGTGCTGGCTGGATATCTCTCGGCTGGTGCAGCAAGATATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0006508 proteolysis biological process None (UniProt)
GO:0008233 peptidase activity molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1Gg1E) rather than this protein.
PDB ID
1Gg1E
Method AlphaFoldv2
Resolution 86.74
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50