Protein

Protein accession
A0A8S5Q6Q8 [UniProt]
Representative
3uV8Y
Source
UniProt (cluster: phalp2_33958)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 95% (predicted by ML model)
Protein sequence
MRIKGFDISRAQENINFDKIEKSGAKFVILRAGIRTDEDTYFRRNLSECQERNIPFGLFWYFEATTDTAFEEELAACKKAVKGLKPAYPIFFDAEEQVQIDNLTTAQRTDMALKFCSEMTAIGLPSGVYANPSWMQNYYDSDRLTGIDIWLAHWTNNPDVPSKFNYGQKIWQWGTEIVDDRKVDSNICFVDYPSLTSKWYKKHGGKTNDSVKTDTKSENKTSCFKSGDKVKVKSGAFFSNGIKPISAVYTAEFVIQRLSKDGTEACIGIDGQDTGWMFCKDLMLSSKKAVSESNTASDSSSINVGDIVRIKSGSKTYDGSSVDDWVYFKRFYVSSVNGKRVVLNKSPDSTVLAINTAFNITDLKKV
Physico‐chemical
properties
protein length:366 AA
molecular weight:41198,0 Da
isoelectric point:8,00
hydropathy:-0,45
Representative Protein Details
Accession
3uV8Y
Protein name
3uV8Y
Sequence length
354 AA
Molecular weight
39995,57960 Da
Isoelectric point
5,27644
Sequence
MRIKGIDISRAQEKFDFTAAQAAGNEFVIIRAGIGKDEDSYFRQNIIECAKRGLAYGCYWYITAVDNAELDSQIKACIKVLDNEKPSYPVFFDMEEQKQIDNLTSKVRTDMAVKFCKSLNEAGLPSGIYANPSWLESYYQKERLVGKYDIWLAHWTESPDYPSRFDYGQKMWQWGVDNIGGKDVDGDICFVDYPAITARWYEEHCIEKPPEKPDDEKHNGFSKGNKVRVKRGAVFTNGVKPYSYVYYTVYTVLQVSGNGKETLIGLDGVPTGWLYTADLYKAEDDTQTQKFVVGDKVKVNYGAKTYNGGALALFVYTNVYEVMQAGSGDREDYIVIGQGGEITAAVRAENLKKI
Other Proteins in cluster: phalp2_33958
Total (incl. this protein): 5 Avg length: 381,6 Avg pI: 7,52
Protein ID Length (AA) pI
3uV8Y 354 5,27644
63Rs5 356 5,18999
63yHS 414 9,54101
6eK0S 418 9,58750
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_6199
5X5xO
 102 34,0% 244 9.610E-41
2 phalp2_10747
3nEcV
 19 30,6% 404 1.621E-32
3 phalp2_26548
858CP
 728 32,5% 227 2.488E-31
4 phalp2_22772
8ond8
 4 27,7% 331 8.362E-31
5 phalp2_10110
c1k0
 16 30,5% 242 2.807E-30
6 phalp2_17584
6pTH5
 130 28,3% 367 9.411E-30
7 phalp2_379
7h79q
 2 25,1% 346 1.570E-24
8 phalp2_35683
3zpKE
 30 32,0% 250 6.468E-21
9 phalp2_36883
7sfSC
 39 30,8% 237 1.168E-20
10 phalp2_9816
8nOwP
 1 23,8% 365 9.213E-20

Domains

Domains [InterPro]
GH25
Unannotated
Unannotated
Representative sequence (used for alignment): 3uV8Y (354 AA)
Member sequence: A0A8S5Q6Q8 (366 AA)
1 354 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Phage sp. ctIHi3
[NCBI] 		2825791 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015582 [NCBI]
CDS location
range 29781 -> 30881
strand +
CDS
ATGAGAATTAAGGGATTTGACATTAGCAGGGCTCAGGAAAACATCAATTTTGATAAAATCGAGAAATCCGGGGCTAAATTTGTTATACTTCGTGCCGGTATACGCACGGACGAAGATACTTATTTCAGACGTAACCTCTCAGAGTGTCAGGAGCGAAATATACCTTTCGGTCTGTTCTGGTATTTCGAAGCCACTACAGACACGGCTTTTGAAGAAGAACTTGCCGCTTGCAAGAAAGCTGTAAAAGGCTTAAAGCCTGCTTATCCGATATTTTTTGACGCTGAAGAACAGGTGCAGATAGATAATCTGACGACTGCACAGCGTACTGACATGGCTTTGAAATTCTGCAGTGAAATGACAGCGATAGGTTTACCGTCCGGCGTGTATGCCAATCCGTCATGGATGCAGAATTACTATGACAGCGATCGCTTAACTGGCATAGATATATGGCTTGCACACTGGACAAATAATCCTGATGTTCCGAGCAAGTTTAACTATGGTCAGAAAATATGGCAGTGGGGAACAGAGATTGTTGATGACAGAAAAGTTGACAGCAACATCTGCTTTGTAGATTATCCTTCACTTACCTCAAAGTGGTATAAGAAGCATGGCGGCAAAACTAACGATTCTGTAAAAACAGATACCAAAAGCGAAAACAAAACATCGTGTTTTAAGTCCGGAGATAAGGTGAAGGTTAAATCAGGAGCATTTTTTTCAAATGGTATAAAGCCTATTTCGGCTGTTTATACCGCTGAATTTGTTATTCAGCGATTATCAAAAGATGGTACAGAAGCCTGCATCGGAATTGATGGACAGGATACCGGATGGATGTTCTGCAAAGATCTTATGCTTTCATCGAAAAAAGCCGTTTCCGAAAGCAACACAGCTTCTGATTCTTCGAGTATAAATGTCGGAGATATCGTTCGAATAAAGAGCGGAAGCAAAACCTATGACGGTTCAAGCGTTGATGACTGGGTTTATTTCAAACGTTTTTATGTTTCAAGCGTAAACGGTAAACGTGTAGTACTTAACAAATCCCCAGATAGCACAGTGCTTGCGATAAATACGGCGTTTAATATTACCGATCTTAAAAAAGTTTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3uV8Y) rather than this protein.
PDB ID
3uV8Y
Method AlphaFoldv2
Resolution 90.01
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50