Protein

Protein accession
A0A8S5PS40 [UniProt]
Representative
c1k0
Source
UniProt (cluster: phalp2_10110)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKKYGLDLSTHNGNVNFNTLKNNGNDFVIIRAGYGSGENQKDGRFEEYYKQAKAHGLKVGAYLYSYALNTSQALDEAKQFCKWLKGKQFDLPVYIDMEDADQYKQKHGMPSNATLSAICETFCNYMETQGYYVGIYASESWLKNQLKEVVSKNKYDLWCANWGTNDGTLQSDKSSVYNLHQFTSMYTLSGKRFDRNVMYYDYPSLIKSKGFNGYSSKPEESNKTVEQLADEVIQGKWGNGAERVTRLTQAGYDATAVQNKVNEKLGVKAKSIDTLAREVIQGKWGNGQDRKDRLTKAGYDYNAIQKRVNEML
Physico‐chemical
properties
protein length:312 AA
molecular weight:35496,3 Da
isoelectric point:8,82
hydropathy:-0,80
Representative Protein Details
Accession
c1k0
Protein name
c1k0
Sequence length
333 AA
Molecular weight
36302,28850 Da
Isoelectric point
8,98349
Sequence
MSYKVIDVSTHQRSINWSAVKASGVDGVIIRAGYGRETSQKDARYEQYYAGAKAAGLKVGAYHYSYADSVADALREADVMLGWLKGKQFDLPIYYDAEESGITTDMVIAYCDKIEKAGYFVGVYASKYWMSNILDYNRIKRFTLWVAQYNSTCTLGKPHDMWQYSSAGSIAGIAGNVDVNHCYRDFAAEIKRAGLNGYRAGTASAPATPASSTGLKYKVGDVVTVSSYYASSTDGSDKAVIPSKWQTGTITRIVPGARNPYLLNNGSLGWCNAGDIRSVQSSSGRTYTVQPGDSWWSIANKQLGDGNRYAELAKYNGMTSGTVIHPGQIIKLP
Other Proteins in cluster: phalp2_10110
Total (incl. this protein): 16 Avg length: 306,4 Avg pI: 7,36
Protein ID Length (AA) pI
c1k0 333 8,98349
1FCXd 336 8,44241
1FDlP 335 8,30412
1FVih 266 7,57677
4SFj1 248 6,10487
5TpJ4 304 8,49263
5Xu98 337 5,28116
6Zbfp 293 5,37193
7BBXz 344 8,61377
7N6rM 293 5,37193
7Vp7D 282 8,90684
7WUhy 279 7,96612
7pdv4 330 5,63970
7pdvc 332 5,71513
8n7J9 279 8,24133
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3425
3TK4D
 923 52,8% 208 8.597E-92
2 phalp2_26548
858CP
 728 38,2% 345 1.435E-87
3 phalp2_1334
14J9Z
 159 41,0% 285 1.507E-76
4 phalp2_2537
6a7No
 192 48,9% 233 2.060E-76
5 phalp2_35683
3zpKE
 30 37,9% 224 5.424E-68
6 phalp2_10747
3nEcV
 19 34,6% 326 7.412E-68
7 phalp2_31512
3WNwM
 280 44,2% 219 1.233E-66
8 phalp2_529
o3Q8
 73 34,5% 292 3.823E-65
9 phalp2_15489
81O6h
 75 36,5% 282 3.823E-65
10 phalp2_34315
3GJC6
 151 29,4% 424 8.666E-64

Domains

Domains [InterPro]
GH25
Unannotated
LysM
Representative sequence (used for alignment): c1k0 (333 AA)
Member sequence: A0A8S5PS40 (312 AA)
1 333 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01476

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctdKF3
[NCBI] 		2825261 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015485 [NCBI]
CDS location
range 1439 -> 2377
strand -
CDS
ATGAAAAAATATGGTTTAGATTTATCAACACATAATGGAAATGTAAATTTTAACACTTTAAAAAACAATGGTAATGATTTTGTGATTATTCGTGCGGGTTATGGAAGTGGCGAAAATCAAAAGGACGGACGTTTTGAAGAATACTACAAACAGGCAAAAGCACACGGTTTAAAAGTTGGTGCTTACTTGTATAGTTACGCATTAAACACAAGTCAAGCATTGGACGAAGCGAAACAATTTTGTAAATGGTTAAAAGGAAAACAATTTGATTTACCCGTTTATATTGACATGGAGGACGCAGACCAATATAAACAAAAACATGGTATGCCGAGCAACGCAACATTAAGCGCAATTTGTGAAACGTTCTGTAATTACATGGAAACGCAAGGTTATTATGTAGGTATTTACGCTAGTGAAAGTTGGTTAAAAAATCAACTTAAAGAAGTTGTTTCAAAAAATAAATATGATTTATGGTGTGCTAATTGGGGTACAAATGACGGTACTTTACAAAGCGATAAGTCAAGTGTTTATAATTTACATCAATTTACAAGTATGTACACATTAAGCGGTAAGCGTTTTGACAGAAACGTAATGTATTATGACTACCCGTCATTGATTAAATCAAAAGGGTTTAACGGTTACAGTTCAAAACCCGAAGAAAGCAATAAAACAGTTGAACAATTAGCCGACGAAGTTATTCAAGGAAAATGGGGCAACGGTGCGGAACGTGTAACAAGATTGACACAAGCGGGTTATGACGCAACGGCAGTTCAAAACAAAGTCAATGAAAAACTAGGTGTCAAAGCAAAGAGTATTGATACACTAGCACGTGAAGTCATTCAAGGAAAATGGGGCAACGGTCAAGACAGAAAAGACCGTTTAACAAAAGCGGGTTACGATTACAACGCTATTCAAAAGCGTGTAAATGAAATGCTTTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (c1k0) rather than this protein.
PDB ID
c1k0
Method AlphaFoldv2
Resolution 90.28
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50