Protein

Protein accession
A0A8S5PIS4 [UniProt]
Representative
41q9o
Source
UniProt (cluster: phalp2_820)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKKGIDISYCQGSPDFAKVRGAVDFVIMQIGYGRFAGQIDKTFARNYSECKKHGIPCGGYWFSYATTADEARAEAKC
Physico‐chemical
properties
protein length:77 AA
molecular weight:8526,6 Da
isoelectric point:8,73
hydropathy:-0,34
Representative Protein Details
Accession
41q9o
Protein name
41q9o
Sequence length
457 AA
Molecular weight
51324,33200 Da
Isoelectric point
7,85833
Sequence
MALMTYDEYFAKTNEKYIDYDGKYGVTCFDLANDYCVKVLGGKQFLGLYAWEIYENFDNQPSKELFTRIKNTPDFVPKKGDIIVWAQSLNGEAGHVEVCTGNGDTTWFESYGQNWTGNHDKCTLLSHNYNHILGVLRPKNQSQIIGKRATTTDNSTKTKSTTLKGIDISRYQGKPDFSKVKNDVDYVILQVGYGRYVNQKDSEFERNYAECKKYGIPVGVYHFSYAKSIAEAQAEANACLEMIKGKQFEYPIYYDLEVGLDSLGKSLVSSIATTFCTALEKAGYYTGIYISRSPAQLYLTKEVAQRYALWLAEYNSKCNYDGNYGMWQYSSTGRVSGINGDVDMDYCYVDYPTLIKNAGLNGYKKPEPTPQPTPTPEKKELDANGYKEGDKGYQALALKTLLKLAIDKGMVSGKLDDTTGLGGGSIKVVNALLKKWGYKENGIAGTNFINRLYKELK
Other Proteins in cluster: phalp2_820
Total (incl. this protein): 8 Avg length: 407,0 Avg pI: 8,25
Protein ID Length (AA) pI
41q9o 457 7,85833
237wR 435 8,21703
24DHx 455 8,71040
3VDZk 454 8,86132
3WDuu 481 8,94062
41fti 455 8,97833
4L7Ys 442 5,69160
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3439
3WDPn
 5 30,5% 288 9.640E-44
2 phalp2_29684
19kq6
 1 30,8% 395 1.207E-41
3 phalp2_12020
7Olig
 697 32,6% 300 3.663E-39
4 phalp2_35723
3WLH4
 2 29,9% 297 2.990E-38
5 phalp2_18915
23B9J
 9 31,4% 299 7.344E-38
6 phalp2_5154
21CAt
 14 31,9% 291 2.432E-37
7 phalp2_18069
3PAN9
 5 25,2% 309 4.865E-25
8 phalp2_35722
3WziM
 1 25,5% 294 2.110E-21

Domains

Domains [InterPro]
Unannotated
GH25
Unannotated
Representative sequence (used for alignment): 41q9o (457 AA)
Member sequence: A0A8S5PIS4 (77 AA)
1 457 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctXBp18
[NCBI] 		2825541 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015442 [NCBI]
CDS location
range 29812 -> >30043
strand +
CDS
ATGAAAAAAGGCATTGACATATCATACTGCCAAGGCTCGCCCGACTTCGCGAAAGTGCGCGGCGCGGTCGATTTCGTGATAATGCAGATAGGCTACGGACGGTTCGCGGGGCAGATAGACAAGACTTTCGCGCGCAACTATTCAGAGTGCAAAAAGCACGGCATACCCTGCGGCGGCTACTGGTTCAGCTATGCGACCACCGCCGACGAGGCGCGCGCCGAAGCAAAGTGCT

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (41q9o) rather than this protein.
PDB ID
41q9o
Method AlphaFoldv2
Resolution 90.95
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50