Protein

Protein accession
A0A8S5NW32 [UniProt]
Representative
1kAmm
Source
UniProt (cluster: phalp2_19076)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MSKYYPDISHHEKVTDWNKVIKACPFIITKATQGLTFVDPLLSTVIKECEKRKKPYWLYAYLNSGKELAQAKFLVETCRERVGKYFVGYILDVECKEGNNVAGVRDALKYISNLGYKSMIYTMYAQYTRYKSVIDKRPKNCAWWEARYGKNNGTYSKKYPTHKGVDFHQFTERGSCPGMSGEIDLNRLTGTKAESWFTDPKISKISNEKTKYPGTFPALPPRGYYQCGDGYETLKDYPTQIRRVQKLLNWVMDADIKVDGKYGANTAALETKLQKKYGLPVNGKFGDKSLAACKKVKK
Physico‐chemical
properties
protein length:298 AA
molecular weight:34140,0 Da
isoelectric point:9,49
hydropathy:-0,66
Representative Protein Details
Accession
1kAmm
Protein name
1kAmm
Sequence length
623 AA
Molecular weight
69716,48090 Da
Isoelectric point
8,16326
Sequence
MRKYYPDISHYRKVTDWGKVKQPCPFIICKATQGTSFVDPTLKEFIDGCEKNEIPYWLYCYLNKGDELPQAEFMVKTCEPLVGNFFVGYALDVEADNTYDGVKKALEFIKTKRPKALLYIGRSFYEKDLFKNIIINRGDNVAFWQARYGKNDGLYETYDYNKYPISPGVDLHQYTSAGNVPGIDKPCDCNMIIGGNKDEAWYTTVAKEEKEEKNMAYTAAAVIAEARKWEGYLEKSKTGTDAQLQSKTWSPGEKNITWFWQWLYNHGLCTKSYLVGAAWCDAFNDYCHAVVGGIDKATKSLGGFSYYTPTSASYYKKAGRWIPANGTPKAGDQIFFKNSTRIYHTGIVIDVTSSKVYTIEGNTSSASGVVENGGCVREKSYSRSSSAIAGYGRPLYDSESNPDLSKGSKGNAVGELQTMLNKVANAKLTVDRDFGSATQKALLAYQKSKGLDADGIYGQKTRAALVADYSKAMNGFNQCVKDFEAWSAETYPGTSKKAIGRTLNSTGYWGENENDKYVALAIFKYNLNDDYNADDLYLDNHNWTKATDEAAARAVLQKGTTANHMTRVLKALLAAQGFYFGKFDGVFDDEVEQAVYAEQKYFGLGQNGKVERRDWKCLFGFGK
Other Proteins in cluster: phalp2_19076
Total (incl. this protein): 2 Avg length: 460,5 Avg pI: 8,83
Protein ID Length (AA) pI
1kAmm 623 8,16326
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_38640
41jQJ
 13 36,0% 408 2.001E-44
2 phalp2_1134
5riG
 24 32,6% 460 5.519E-38
3 phalp2_34377
4dm6y
 15 31,0% 480 1.595E-30
4 phalp2_34762
3ij83
 364 29,5% 423 8.107E-28
5 phalp2_16417
6gC98
 231 28,6% 405 3.364E-22
6 phalp2_3229
2bNef
 21 27,2% 513 1.031E-21
7 phalp2_15784
3ZRUV
 1 23,4% 529 2.432E-10

Domains

Domains [InterPro]
GH25
Unannotated
PG_1
PG_1
Representative sequence (used for alignment): 1kAmm (623 AA)
Member sequence: A0A8S5NW32 (298 AA)
1 623 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctQLz13
[NCBI] 		2825492 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015262 [NCBI]
CDS location
range 12968 -> 13864
strand +
CDS
GTGAGCAAATATTATCCAGACATCTCGCACCATGAAAAAGTAACGGACTGGAATAAAGTTATAAAAGCCTGTCCGTTTATTATCACGAAAGCAACACAGGGATTAACATTCGTTGATCCGTTATTAAGCACCGTAATAAAGGAATGTGAAAAAAGGAAGAAACCATATTGGCTGTACGCTTATTTGAACAGTGGCAAAGAACTTGCACAGGCGAAATTCTTAGTGGAAACGTGCAGAGAAAGAGTTGGAAAGTATTTCGTTGGCTATATTCTCGATGTGGAATGTAAGGAAGGGAATAACGTAGCAGGTGTTAGGGATGCTCTTAAATACATCAGCAATCTTGGCTATAAGTCAATGATCTACACGATGTATGCACAGTACACAAGATATAAGAGTGTTATTGATAAGCGGCCAAAGAACTGTGCCTGGTGGGAAGCAAGGTATGGAAAGAACAATGGAACATACAGTAAGAAGTATCCGACACATAAAGGTGTTGACTTCCATCAGTTCACAGAACGAGGAAGCTGTCCGGGGATGAGCGGTGAGATTGACCTTAATAGACTGACCGGAACAAAAGCGGAAAGCTGGTTCACTGACCCGAAGATAAGCAAGATAAGCAATGAAAAGACAAAGTATCCAGGAACATTTCCGGCATTACCACCACGTGGTTACTATCAGTGCGGCGATGGATACGAAACATTGAAGGACTATCCAACACAGATCAGGAGAGTACAGAAACTGCTTAACTGGGTGATGGATGCAGATATCAAAGTGGATGGAAAATACGGAGCGAATACAGCGGCATTAGAAACGAAGCTACAGAAAAAATATGGATTGCCTGTTAACGGTAAGTTTGGAGATAAGTCACTTGCAGCATGTAAGAAGGTAAAGAAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1kAmm) rather than this protein.
PDB ID
1kAmm
Method AlphaFoldv2
Resolution 82.19
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50