Protein

Protein accession
A0A8S5NIS0 [UniProt]
Representative
3sMIn
Source
UniProt (cluster: phalp2_34301)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MALIAAMCMMTLPATAHADMQGVDMSNWQCGADVYNMQADFIVVGTTWGTGQVYNNCLVSGVNTDANRMIAQAQASGKKFGLYHYAMGGNPEAEARFFYANTLNYWRHGIVALDWEMDDNPAWGDWDWVRRFMAECERLSGGVRPLLYTGPVAGTIPQDIRDRYGLWIAQYANMSPTGYQANPWMIGAYGEAMRQYSGTGVVNTWSPIDLNLFRGEAWQWDLYANPTGGSTPPATPAAPVQPSNPQPTPSTGGISHTMRWGETIWGLAVAYNAWPLSAWHTPSGDINRYYVGDVVTYGGGTAPASSTGVSKVLQWGDTVWEFATSHGYSVSRCTVPSGNINVYYVGDVVTCR
Physico‐chemical
properties
protein length:352 AA
molecular weight:38530,7 Da
isoelectric point:5,03
hydropathy:-0,22
Representative Protein Details
Accession
3sMIn
Protein name
3sMIn
Sequence length
220 AA
Molecular weight
23757,13360 Da
Isoelectric point
5,37369
Sequence
MNECERLSGGVRPLLYTGPVAGTIPQDIRDRYGLWIAQYANMSPTGYQASPWMLGAYGEAMRQYSGTGVVNTWSPIDLNIFRGEAWQWDLYANPTGSTAPAPATPAPVQPSTPPANTNTGGISHVMQWGETIWGLAVAHNAWPLSAWHTPSGDINRYYVGDVVTYGGGSTTAPSHGVSKVLQWGDTVWEFATSHGYNVSQCTVPSGNINVYYPGDVVTCR
Other Proteins in cluster: phalp2_34301
Total (incl. this protein): 6 Avg length: 304,5 Avg pI: 5,45
Protein ID Length (AA) pI
3sMIn 220 5,37369
1lXiA 201 4,83066
5XOBo 389 5,46532
61FQj 371 6,22617
6rpc2 294 5,76009
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_17204
3jHSi
 3 90,2% 134 2.122E-85
2 phalp2_12160
6ljWQ
 2 36,6% 139 4.743E-20
3 phalp2_13670
5RffS
 11 34,1% 205 6.520E-18
4 phalp2_4894
5TthI
 1 30,6% 147 2.623E-08

Domains

Domains [InterPro]
Unannotated
Unannotated
Unannotated
Representative sequence (used for alignment): 3sMIn (220 AA)
Member sequence: A0A8S5NIS0 (352 AA)
1 220 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctfdk3
[NCBI] 		2826416 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015178 [NCBI]
CDS location
range 25240 -> 26298
strand +
CDS
ATGGCGCTGATCGCCGCCATGTGCATGATGACGCTCCCCGCGACCGCCCACGCGGACATGCAGGGCGTGGACATGTCCAACTGGCAGTGCGGCGCTGACGTGTACAACATGCAGGCCGACTTCATCGTGGTCGGCACCACGTGGGGCACGGGACAGGTGTACAACAACTGCCTCGTGTCCGGCGTCAACACGGATGCGAACCGTATGATCGCCCAGGCGCAGGCATCCGGCAAGAAATTCGGCCTCTACCATTACGCCATGGGCGGCAACCCCGAGGCCGAGGCCCGGTTCTTCTACGCCAACACGTTGAACTATTGGCGTCACGGCATCGTCGCCCTTGACTGGGAGATGGACGACAATCCCGCATGGGGTGATTGGGATTGGGTGCGCCGGTTCATGGCTGAGTGTGAACGGCTTTCGGGCGGTGTGCGCCCATTGCTGTACACCGGCCCGGTGGCCGGCACCATCCCGCAGGACATCCGCGACCGATACGGTTTGTGGATCGCCCAGTACGCGAACATGAGCCCGACCGGCTATCAGGCCAATCCGTGGATGATCGGCGCATACGGCGAGGCCATGCGACAGTACAGTGGTACCGGTGTCGTCAACACGTGGAGTCCCATCGACCTCAACCTGTTCCGCGGCGAGGCATGGCAGTGGGATCTGTACGCCAACCCGACCGGCGGCTCCACGCCACCGGCCACACCGGCCGCGCCCGTGCAGCCGAGCAACCCCCAGCCCACTCCCAGCACTGGAGGCATCAGCCACACCATGCGGTGGGGCGAGACCATCTGGGGACTCGCCGTCGCCTACAACGCATGGCCCCTGTCCGCATGGCACACGCCAAGCGGTGACATCAACCGCTACTACGTGGGCGATGTCGTCACCTACGGCGGCGGCACCGCCCCCGCATCGTCCACCGGGGTATCCAAGGTCCTCCAATGGGGCGACACCGTGTGGGAGTTCGCCACGTCCCACGGCTACAGCGTCAGCCGCTGCACCGTCCCCTCCGGCAACATCAACGTCTACTATGTGGGCGACGTGGTGACCTGCCGCTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3sMIn) rather than this protein.
PDB ID
3sMIn
Method AlphaFoldv2
Resolution 74.14
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50