Protein

Protein accession
A0A8S5NG23 [UniProt]
Representative
89f4d
Source
UniProt (cluster: phalp2_14039)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAREIMIDLASYQANLTANDYRAIGATKAIVKVTESTNYVNPYIQSEVNNAAAGGVNGFAFYHFGRFTNDAGAKAEAEFFIANAKAKANVKPGTLLVIDAEINNMPTSSVIVFLDTLRNAGYHTGFYTYKYLLPKFDLEAIHPHCDFFWLAAYVLANGKADGKEPNFNYFPSANYVDAWQYTDNLLGYKVDGSITLTDNALALFNPTEVKQPEQPAQPANKPAETVWKDALGDEWHAESGTFTSTTALHLRWGAKVTATSIAVLPSGSVIKYDAWSRHNGFVWLRQPRGNGQYGYLVCRNANTGEPYGTFK
Physico‐chemical
properties
protein length:311 AA
molecular weight:34301,0 Da
isoelectric point:6,17
hydropathy:-0,26
Representative Protein Details
Accession
89f4d
Protein name
89f4d
Sequence length
178 AA
Molecular weight
20045,24890 Da
Isoelectric point
6,05463
Sequence
MANREVVIDLASFQSELTVQDYKNIGATKAIVKISENTNYVNPYIRSLIDRSAGGGVNGFAFYHFGRFYNDSAAVAEANYFIENAKRYANVQPGTLLILDAEIKGMPTSSVIAFLQTLRNAGYHTGFYTYKFLLPQFNLEEIHKYADFFWLAAYPLGDQPGPRVPDFNYFPSANNQHS
Other Proteins in cluster: phalp2_14039
Total (incl. this protein): 3 Avg length: 233,3 Avg pI: 5,68
Protein ID Length (AA) pI
89f4d 178 6,05463
6dgY1 211 4,81070
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12156
6iQWP
 264 35,7% 176 6.187E-20
2 phalp2_37341
8v6XY
 562 28,8% 170 2.178E-12
3 phalp2_22092
5WvnN
 1 29,1% 185 7.468E-12
4 phalp2_36241
7z7Vw
 21 28,3% 141 7.239E-08
5 phalp2_20117
23DDy
 70 27,8% 151 1.329E-07
6 phalp2_20361
2Sd5N
 42 30,1% 159 6.044E-07

Domains

Domains [InterPro]
GH25
Disordered region
Representative sequence (used for alignment): 89f4d (178 AA)
Member sequence: A0A8S5NG23 (311 AA)
1 178 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. cte0p10
[NCBI] 		2826674 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015156 [NCBI]
CDS location
range 4171 -> 5106
strand -
CDS
ATGGCACGCGAAATCATGATTGATCTGGCTAGTTATCAAGCTAACCTGACCGCTAACGATTACCGCGCAATTGGCGCTACTAAGGCAATCGTTAAGGTTACGGAAAGCACTAACTACGTCAACCCTTATATTCAAAGCGAAGTAAATAATGCTGCTGCGGGTGGTGTTAACGGCTTTGCTTTCTACCATTTCGGACGGTTCACGAATGACGCCGGAGCAAAGGCGGAAGCTGAGTTTTTCATTGCCAACGCTAAGGCAAAGGCAAACGTCAAGCCTGGCACGCTGTTAGTCATTGATGCTGAAATCAACAACATGCCAACGTCAAGCGTTATCGTGTTCTTGGACACGTTGCGCAACGCTGGTTATCACACCGGATTTTATACCTACAAGTATCTGCTGCCTAAGTTTGATCTGGAAGCAATCCACCCACACTGCGATTTCTTTTGGCTTGCTGCATACGTACTGGCAAACGGTAAAGCAGACGGTAAAGAGCCTAACTTTAACTACTTCCCAAGTGCCAACTATGTTGACGCATGGCAGTACACTGATAACCTGTTAGGCTACAAGGTTGACGGGTCTATCACGCTGACTGACAACGCTTTGGCACTGTTTAACCCAACCGAAGTTAAGCAACCGGAACAGCCTGCACAACCGGCTAACAAGCCCGCTGAAACGGTCTGGAAGGACGCACTGGGCGATGAGTGGCACGCTGAAAGTGGTACGTTCACGAGTACAACGGCACTTCATCTACGGTGGGGTGCTAAAGTAACCGCAACGTCAATCGCTGTATTGCCTTCTGGTAGCGTGATTAAGTATGACGCATGGAGCCGTCATAACGGGTTCGTTTGGCTGCGTCAACCACGTGGCAACGGGCAATATGGCTATCTGGTATGCCGAAACGCTAACACCGGCGAGCCTTACGGCACTTTCAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (89f4d) rather than this protein.
PDB ID
89f4d
Method AlphaFoldv2
Resolution 87.29
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50