Protein

Protein accession
A0A8S5NCP5 [UniProt]
Representative
6lvSt
Source
UniProt (cluster: phalp2_5947)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTDINFTQCWNYTRGREGREPSKIVIHHWGSDGQTHEGVVDFFTRGPGSGTSAHYVVSAGKITQICHDYDTAYHAGNWNANLDSIGIECRPEATEEDVRTVAELVRRIRAEWGYMPLTVHSDYYPTACPGRYHSLIDRINQLAQEEESDMQLTDRITRPDGHNASVGDILAYVDMRVERLEAVLIGGVEKKGKDGAPTGARTNISDEAAWNATNFARVYDSLAALTKRVDDLVNLIEVGASK
Physico‐chemical
properties
protein length:242 AA
molecular weight:26898,5 Da
isoelectric point:5,25
hydropathy:-0,51
Representative Protein Details
Accession
6lvSt
Protein name
6lvSt
Sequence length
162 AA
Molecular weight
17753,76650 Da
Isoelectric point
5,04443
Sequence
MRTIGIECHPAALDGDMKTIARLIAAIRSEWGPLPLSRHCDHFATACPGNYKDKLETLDYLATHEGDNDMQLSDQVTRPDGHTATVNDVLAYIDMRIERIESVLIGGQDKKGEDGKPTGARTNVFDEAAWNATNFARVYAGIEALSKRVDDLVNLIEVGASK
Other Proteins in cluster: phalp2_5947
Total (incl. this protein): 2 Avg length: 202,0 Avg pI: 5,15
Protein ID Length (AA) pI
6lvSt 162 5,04443
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_866
8bEwv
 56 77,7% 162 4.229E-87

Domains

Domains [InterPro]
Unannotated
Unannotated
Disordered region
Representative sequence (used for alignment): 6lvSt (162 AA)
Member sequence: A0A8S5NCP5 (242 AA)
1 162 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctFmt20
[NCBI] 		2826214 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015129 [NCBI]
CDS location
range 10396 -> 11124
strand +
CDS
ATGACAGATATCAATTTCACACAGTGCTGGAATTACACGCGAGGCCGCGAAGGCCGCGAACCGTCAAAAATCGTCATTCATCATTGGGGATCCGACGGACAAACTCACGAGGGAGTCGTCGACTTCTTTACACGCGGCCCCGGCTCTGGAACTAGCGCTCATTATGTTGTAAGTGCAGGCAAGATCACTCAGATCTGCCACGATTACGACACTGCATATCACGCGGGAAACTGGAACGCGAACCTCGACTCGATCGGCATCGAATGCCGCCCCGAGGCAACCGAGGAAGATGTTCGCACAGTCGCCGAGCTGGTCCGCCGTATCCGCGCAGAGTGGGGATACATGCCGCTCACCGTTCACAGCGACTACTACCCGACCGCGTGCCCGGGACGCTATCACTCTCTCATCGACCGAATCAACCAATTAGCACAGGAAGAGGAATCCGACATGCAACTAACCGACCGTATTACGCGCCCTGATGGGCACAACGCGAGCGTGGGAGACATTCTCGCGTACGTTGATATGCGAGTAGAGCGCCTCGAAGCCGTCCTCATTGGAGGAGTGGAAAAGAAAGGAAAAGACGGAGCACCAACCGGCGCGCGGACGAACATCTCGGACGAGGCAGCGTGGAACGCCACGAACTTTGCCCGAGTTTACGACTCTCTCGCAGCTTTGACGAAGCGCGTAGATGATCTTGTGAATCTGATCGAGGTAGGAGCCTCAAAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0009254 peptidoglycan turnover biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6lvSt) rather than this protein.
PDB ID
6lvSt
Method AlphaFoldv2
Resolution 87.20
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50