Protein

Protein accession
A0A8S5N4Z9 [UniProt]
Representative
8tSTN
Source
UniProt (cluster: phalp2_24098)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MKTFFDFISKLLAALSHAASDKAAEPDSPAPEKVSTVDTVPGWTGEPPYRYLDVSRWQGKIKMEGWAAIKDAGYKGVMLRACGNSASYSPSKAYIDPTFEKNYANAKAAGLDIGVYYFTKAVSEAEADKELAVLRHALRGKELTMPVAVDMEDVMLTFHKPKDLTNLAAYHLEQIEKMGFFAQFYTYTSYANCYLEMERLAGRWDVWLADYTGKTPKVDFHYGAHQHTSEGSVPGISGSVDLNVTTLNYPRIIRKKGLTRLREGA
Physico‐chemical
properties
protein length:265 AA
molecular weight:29518,2 Da
isoelectric point:7,06
hydropathy:-0,34
Representative Protein Details
Accession
8tSTN
Protein name
8tSTN
Sequence length
119 AA
Molecular weight
13642,32530 Da
Isoelectric point
9,52013
Sequence
MRWNVEENKLKQLSTLDLSNLTAYALEQVERMGFYAQLYTYTSYANTHLDMARLSGRWDVWLADYTGKTPNVTFNYNAHQHTSKGVVPGISGNVDLNVTTLNYPKIIRKKGLARLREGK
Other Proteins in cluster: phalp2_24098
Total (incl. this protein): 7 Avg length: 146,4 Avg pI: 8,03
Protein ID Length (AA) pI
8tSTN 119 9,52013
3k4nX 121 7,93008
5KhIs 88 9,09837
6a1dC 140 8,77771
6gfCs 152 6,91500
6tcah 140 6,90965
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11208
6hYV2
 1315 66,6% 117 4.149E-47
2 phalp2_27618
64CP8
 10 54,4% 79 3.123E-16
3 phalp2_22731
85jlZ
 4 32,1% 112 2.389E-10
4 phalp2_10527
83k5k
 1 31,5% 95 1.150E-09
5 phalp2_31693
3k10b
 2 28,8% 118 2.657E-08
6 phalp2_36234
7vdI3
 1 30,9% 113 4.830E-05

Domains

Domains [InterPro]
GH25
Representative sequence (used for alignment): 8tSTN (119 AA)
Member sequence: A0A8S5N4Z9 (265 AA)
1 119 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Caudovirales sp. ctXjW8
[NCBI] 		2826779 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015067 [NCBI]
CDS location
range 11417 -> 12214
strand +
CDS
ATGAAAACATTCTTTGATTTTATCTCCAAGCTGCTGGCAGCCCTCTCCCACGCTGCCAGCGACAAGGCAGCGGAGCCGGACTCCCCCGCCCCTGAAAAAGTGTCCACTGTGGACACCGTGCCCGGCTGGACGGGCGAGCCGCCCTACCGCTACCTCGACGTGAGCCGGTGGCAGGGAAAAATCAAAATGGAGGGATGGGCGGCCATCAAGGACGCAGGCTACAAGGGCGTCATGCTGCGGGCCTGCGGGAACAGTGCCAGCTACAGCCCCAGCAAGGCATACATTGACCCGACTTTCGAGAAGAACTACGCCAACGCTAAGGCGGCCGGGCTGGATATTGGCGTCTACTATTTCACGAAGGCCGTGAGCGAGGCAGAGGCCGACAAGGAGCTTGCGGTACTGCGGCATGCGCTGCGGGGCAAAGAGCTGACCATGCCGGTGGCGGTGGACATGGAAGACGTCATGCTTACTTTTCACAAGCCGAAAGACCTGACCAACCTCGCGGCATACCACCTTGAGCAGATCGAGAAGATGGGGTTCTTCGCCCAGTTTTACACCTACACGAGCTACGCCAACTGCTACCTTGAGATGGAGCGTCTGGCTGGGCGGTGGGATGTGTGGCTTGCAGACTACACGGGCAAGACGCCTAAGGTAGACTTCCATTACGGCGCACACCAGCACACCAGCGAGGGCTCTGTGCCGGGCATTTCCGGCAGCGTAGACCTCAACGTGACCACCCTCAACTACCCCCGCATCATCCGCAAGAAGGGTCTGACCCGTCTCCGGGAGGGCGCATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8tSTN) rather than this protein.
PDB ID
8tSTN
Method AlphaFoldv2
Resolution 83.76
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50