Protein

Protein accession
A0A8S5N0Y2 [UniProt]
Representative
6aH2F
Source
UniProt (cluster: phalp2_39574)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNGIDISAWQGDKNIDLAKVPYDFCIVKATEGTDYKNRYFTAHCDAVLKKKKLLGAYHYANGGNPQKEADYFLAYCKKYIGKAILVLDWEAKNNPQFGKNDLEWCLKWCRYVQSKTGVKPLIYVQKSAMDAVKKAGYGLWVAQYPDYEQTGYQEHPWNEGAYNCLLRQYTSVGKLSGYSGSLDLNKAYIGAASWRKLATKAVKIATIKPVKKSVNTIAREVLAGKWGNGADRKSRLTKAGYDYSKVQAAVNKLVKASQMTQDKIINAVAHEVIIGKWSNGQERIDRLKAAGYDPDKIQERVNEIMM
Physico‐chemical
properties
protein length:306 AA
molecular weight:34451,2 Da
isoelectric point:9,43
hydropathy:-0,51
Representative Protein Details
Accession
6aH2F
Protein name
6aH2F
Sequence length
178 AA
Molecular weight
19774,37180 Da
Isoelectric point
9,83892
Sequence
MNAVKKAGYGLWVAQYPDYEQTGYQEHPWNEEAYNCLIRQYTSVGKLTGYSGNLDLNKAYISSASWRKLATKAVKTAAIKPVKKSVNAIAREVLAGKWGNGADRKARLTKAGYDYNKVQAAVNKLVKASQITQGKIINAVAHEVIAGRWGNGQERIDRLKAAGYDPDKIQKRVNELMK
Other Proteins in cluster: phalp2_39574
Total (incl. this protein): 4 Avg length: 223,0 Avg pI: 9,40
Protein ID Length (AA) pI
6aH2F 178 9,83892
41drY 207 9,24298
6cXKh 201 9,09586
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36902
7xnld
 3 42,9% 170 3.209E-31
2 phalp2_15733
3lliN
 3 42,9% 170 6.012E-31
3 phalp2_29818
23Cvi
 2 33,1% 169 1.373E-26
4 phalp2_17221
3xRQT
 3 35,3% 147 1.777E-20
5 phalp2_5164
24ATP
 1 34,0% 144 1.087E-16
6 phalp2_2549
6lVrL
 1 28,6% 136 8.598E-09

Domains

Domains [InterPro]
Unannotated
CW_7
CW_7
Representative sequence (used for alignment): 6aH2F (178 AA)
Member sequence: A0A8S5N0Y2 (306 AA)
1 178 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF08230

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctpbb7
[NCBI] 		2826465 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015035 [NCBI]
CDS location
range 26194 -> 27114
strand +
CDS
ATGAATGGTATAGACATTAGTGCCTGGCAGGGGGATAAAAATATAGACCTTGCCAAAGTGCCATACGATTTTTGCATCGTAAAGGCGACAGAGGGAACAGACTACAAGAACAGATATTTTACAGCGCATTGTGATGCTGTTTTGAAGAAAAAGAAGCTGCTGGGTGCATACCACTATGCCAACGGCGGAAATCCCCAGAAAGAGGCTGACTACTTCTTGGCATACTGTAAGAAGTACATCGGAAAAGCAATCCTTGTGCTTGACTGGGAGGCAAAGAATAACCCTCAGTTTGGCAAGAACGATCTTGAATGGTGCTTGAAGTGGTGCAGATATGTACAGAGTAAGACAGGCGTCAAGCCGTTAATCTACGTGCAGAAGAGTGCCATGGACGCAGTAAAGAAAGCTGGATATGGCCTGTGGGTGGCTCAGTACCCAGACTATGAGCAGACTGGTTATCAGGAGCATCCGTGGAACGAGGGAGCTTATAACTGTTTACTCAGACAGTACACATCTGTCGGAAAGCTCTCAGGTTACAGCGGCAGCCTTGATCTCAACAAGGCATATATCGGCGCTGCATCATGGCGCAAGCTGGCTACTAAGGCTGTGAAGATTGCCACTATTAAGCCAGTAAAGAAGAGTGTCAATACGATCGCAAGGGAAGTACTTGCTGGCAAGTGGGGCAATGGTGCTGATCGCAAGAGCAGATTGACAAAGGCTGGATATGACTATAGCAAGGTTCAGGCAGCAGTCAACAAACTTGTCAAGGCATCACAGATGACACAGGATAAGATCATCAATGCAGTTGCGCATGAAGTCATCATAGGCAAGTGGAGCAATGGACAGGAACGTATTGACAGGCTTAAGGCAGCAGGCTACGATCCAGACAAGATTCAGGAAAGGGTTAATGAGATCATGATGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6aH2F) rather than this protein.
PDB ID
6aH2F
Method AlphaFoldv2
Resolution 82.96
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50