Protein

Protein accession
A0A8S5MIT0 [UniProt]
Representative
1IrSm
Source
UniProt (cluster: phalp2_33872)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 96% (predicted by ML model)
Protein sequence
MKTISDKGLKFIQVNEGVAKGSFDGQKFKSYFDKIGNKWTIAWGLTYINGKPVTKDTVLTINEANIAFRHHLSSNEKAINDLMIRDSIVLTQNEFDALIDFVYNIGNGHADCDVWKAVKTHDSLKIEQAFLAHNKVGGKYNQGLANRRKKEIALFSQARYGSY
Physico‐chemical
properties
protein length:163 AA
molecular weight:18388,7 Da
isoelectric point:9,34
hydropathy:-0,41
Representative Protein Details
Accession
1IrSm
Protein name
1IrSm
Sequence length
46 AA
Molecular weight
5284,94370 Da
Isoelectric point
10,09029
Sequence
VKTHDFSKIEQAFLAHNKVGGKYNQGLANRRKKEIALFTQARYGSY
Other Proteins in cluster: phalp2_33872
Total (incl. this protein): 2 Avg length: 104,5 Avg pI: 9,72
Protein ID Length (AA) pI
1IrSm 46 10,09029
Similar Clusters

No similar clusters were found for representative 1IrSm.

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 1IrSm (46 AA)
Member sequence: A0A8S5MIT0 (163 AA)
1 46 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctvyM23
[NCBI] 		2826514 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014908 [NCBI]
CDS location
range 3905 -> 4396
strand +
CDS
ATGAAAACAATCAGCGATAAAGGTTTGAAATTCATTCAGGTAAACGAAGGTGTTGCTAAAGGCTCCTTTGATGGTCAGAAGTTCAAAAGTTATTTTGACAAAATCGGCAATAAATGGACTATTGCCTGGGGACTAACTTATATCAACGGTAAGCCTGTGACAAAAGATACAGTCCTAACAATCAATGAAGCGAATATCGCATTTAGACATCACTTAAGTTCAAACGAAAAAGCAATTAACGATTTGATGATTAGAGATTCAATCGTACTTACTCAGAATGAATTTGATGCGCTTATAGATTTTGTTTACAACATCGGAAACGGTCATGCTGATTGTGATGTATGGAAAGCTGTTAAGACGCATGACAGTTTAAAAATTGAACAAGCATTTTTAGCTCATAACAAGGTAGGCGGTAAATACAATCAGGGTTTAGCTAACAGACGAAAGAAAGAAATCGCTTTATTTTCTCAGGCAAGATATGGAAGTTATTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1IrSm) rather than this protein.
PDB ID
1IrSm
Method AlphaFoldv2
Resolution 70.85
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50