Protein

Protein accession
A0A8S5LYH1 [UniProt]
Representative
8HjXQ
Source
UniProt (cluster: phalp2_23657)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKCSFSDAYLALLREFEGLFLRPYLCPAGYCTIGYGSNLEAHPRFIPFEDIRGRVQRGGLRGASLLLVLRDRGMTWTREQAEEAMLWELQATNADLLQRCPVYATLRNGGDNVRADALLDMAYNMGVGRARDKARGIKGSGLLGFYTTLPMIGRGEYVRAAENLRSSVWYHQTGRRARAICSMIATGRYPERLR
Physico‐chemical
properties
protein length:194 AA
molecular weight:21863,0 Da
isoelectric point:9,63
hydropathy:-0,27
Representative Protein Details
Accession
8HjXQ
Protein name
8HjXQ
Sequence length
88 AA
Molecular weight
9587,17170 Da
Isoelectric point
9,91493
Sequence
MADLDAKLPWWRQLDEVRQRVIVNMCFNMGIGNAALGKGLLGFVNTLAKVKAGDYQGAADGMKASKWYGQVGARAERLVKMMRTGVAA
Other Proteins in cluster: phalp2_23657
Total (incl. this protein): 36 Avg length: 112,8 Avg pI: 6,94
Protein ID Length (AA) pI
8HjXQ 88 9,91493
1VxDf 140 5,05352
1Y1Ws 61 5,51426
1fmlD 88 6,76670
1sTuW 140 4,96099
1vsqE 111 4,55516
26FOR 138 4,33928
28kq1 92 8,98078
2cmWe 84 10,63775
2lLPa 136 6,41322
3EA9z 62 8,09982
3HMQh 145 7,73405
3NH9p 152 5,45287
3RgGA 55 9,76885
3ejko 106 9,18289
4Bgka 69 11,25181
4FkvW 99 5,80613
4I2Nz 137 4,95803
4RQYF 145 4,95468
4TKil 139 5,04414
4Ugdv 98 9,13564
4imFq 92 9,30035
5rudM 70 9,52180
6AwWi 96 7,84621
6Inbw 97 9,04255
7tq46 101 10,27944
814sl 141 4,84708
852qz 139 4,84248
85Odq 90 5,23308
8EMPu 78 4,92683
8Ehau 106 5,85091
8bL7N 145 4,95468
8gTp2 141 4,75011
8pjwq 138 4,33780
8tuMj 146 6,11692
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_25441
2RHwi
 57 59,2% 81 4.797E-33
2 phalp2_11817
8ke1T
 134 47,4% 78 2.946E-31
3 phalp2_22992
3CfKl
 406 30,3% 79 2.824E-23
4 phalp2_473
8zCRl
 299 39,5% 81 4.506E-21
5 phalp2_24916
8DwFO
 101 45,9% 61 8.497E-21
6 phalp2_18224
4OOGY
 8 52,4% 61 7.822E-20
7 phalp2_11147
5zMFW
 8 46,0% 76 3.819E-19
8 phalp2_36345
lSw4
 8 35,8% 67 9.890E-19
9 phalp2_4036
185uE
 1 31,3% 83 2.561E-18
10 phalp2_27263
46PtW
 81 40,9% 61 3.517E-18

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 8HjXQ (88 AA)
Member sequence: A0A8S5LYH1 (194 AA)
1 88 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctrnx29
[NCBI] 		2826704 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014766 [NCBI]
CDS location
range 37779 -> 38363
strand -
CDS
ATGAAATGTTCTTTTTCTGACGCCTATCTGGCGTTGCTGCGAGAGTTTGAAGGCCTTTTTCTGCGGCCCTACCTTTGTCCGGCAGGTTATTGCACTATCGGATACGGAAGCAATCTTGAGGCGCACCCGCGTTTCATCCCATTTGAGGACATACGTGGACGCGTCCAGCGCGGTGGGCTGCGTGGGGCGAGTCTGCTGCTGGTTCTGCGCGATCGCGGCATGACGTGGACCAGGGAGCAGGCTGAGGAGGCCATGCTGTGGGAGTTGCAGGCGACCAATGCTGACCTGCTGCAACGCTGTCCGGTTTATGCCACTCTGCGAAACGGTGGTGATAACGTGAGGGCCGATGCCCTGCTGGACATGGCCTACAACATGGGCGTGGGCCGCGCCCGGGACAAGGCGCGGGGCATTAAGGGGAGCGGCCTGCTTGGCTTTTATACGACCCTGCCCATGATCGGGCGCGGGGAATACGTCCGCGCCGCTGAAAACCTCAGGAGTTCTGTCTGGTATCACCAGACAGGACGACGCGCCCGCGCCATCTGTTCCATGATAGCCACGGGACGATACCCAGAGCGGCTGCGATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8HjXQ) rather than this protein.
PDB ID
8HjXQ
Method AlphaFoldv2
Resolution 97.18
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50