Protein

Protein accession
A0A8S5LR62 [UniProt]
Representative
64CP8
Source
UniProt (cluster: phalp2_27618)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSEKTIMDVSRWQGRIDWDAVKRSGKIDGVMLRVLGSKGGKPYLDPYFARNYAECARLGIPVGGYYYTCAVTPRQTAAELAALRAALKGKSFQLPIAVDAEDPKLRGLTPAKLSARVAEAAAKLEAWGLYAMVYTYTNFADTALDMDALTAYDLWIADYRGHRPTRKHGMWQYTSKGKIPGVNGPVDLSHAYKDYPAIIQRAGLTKVKGV
Physico‐chemical
properties
protein length:210 AA
molecular weight:23153,4 Da
isoelectric point:9,52
hydropathy:-0,26
Representative Protein Details
Accession
64CP8
Protein name
64CP8
Sequence length
79 AA
Molecular weight
8869,95140 Da
Isoelectric point
9,34484
Sequence
MVYTYTNFADTALDMEALAAYDLWIADYRGKRPARRHGMWQYTSSGKIHGVSGPVDLSHAYKDYATIIQRAGLTKVRGA
Other Proteins in cluster: phalp2_27618
Total (incl. this protein): 10 Avg length: 111,5 Avg pI: 9,02
Protein ID Length (AA) pI
64CP8 79 9,34484
14QBe 90 4,90386
3phK3 96 9,76362
3zsYO 99 9,33542
668Rn 96 8,92824
6v8Q9 64 10,22902
6vSqO 87 9,58821
8tO6g 85 9,45527
A0A8S5MVE9 209 9,15182
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24098
8tSTN
 7 44,3% 79 1.983E-20
2 phalp2_6948
2Veum
 1 34,3% 67 1.467E-08
3 phalp2_39217
3qhjn
 1 30,3% 79 2.220E-05

Domains

Domains [InterPro]
GH25
Representative sequence (used for alignment): 64CP8 (79 AA)
Member sequence: A0A8S5LR62 (210 AA)
1 79 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctSGr1
[NCBI] 		2827609 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015900 [NCBI]
CDS location
range 20193 -> 20825
strand +
CDS
ATGAGTGAAAAAACGATTATGGACGTATCCCGTTGGCAGGGCCGCATCGACTGGGACGCGGTGAAGCGCAGCGGCAAAATCGACGGCGTGATGCTCCGGGTGCTGGGCAGCAAGGGCGGCAAGCCCTACCTCGACCCCTATTTCGCCCGCAACTACGCCGAGTGTGCCCGGCTGGGCATCCCGGTGGGCGGTTACTACTACACCTGTGCCGTCACGCCCCGGCAGACGGCCGCAGAGCTGGCCGCCCTGCGTGCTGCGCTGAAGGGCAAGAGCTTCCAACTGCCAATCGCGGTGGATGCAGAAGATCCGAAGCTGCGCGGTCTGACCCCGGCCAAGCTGTCCGCCCGCGTGGCCGAAGCCGCCGCCAAGCTCGAAGCGTGGGGGCTGTATGCAATGGTGTACACCTACACCAATTTCGCGGACACCGCCCTCGACATGGATGCGCTGACCGCCTATGACCTTTGGATCGCAGACTACCGCGGCCACCGTCCCACCCGCAAGCACGGCATGTGGCAGTACACCAGCAAGGGCAAGATCCCCGGTGTGAACGGCCCGGTAGACCTGAGCCATGCCTACAAGGACTACCCGGCCATCATCCAGCGGGCCGGATTGACAAAAGTGAAGGGAGTATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (64CP8) rather than this protein.
PDB ID
64CP8
Method AlphaFoldv2
Resolution 95.76
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50