Protein

Protein accession
A0A8S0HWZ4 [UniProt]
Representative
3FVpv
Source
UniProt (cluster: phalp2_3395)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MDTHTIGYGHLVTPDEKIPNTISRAFAEQLFNKDYKHHKQAAQGIPGYDNLSLQQKAAMIDLTFNMGPEWHKEFPLMMAALQKKDYNTAAAELKNSLYYNQVGRRGVTTVSLMKNQGVADYLRVLNIIPPAGSDQNKRNFGFAPIFNMLLGAQPAGASEIDGFNQKVQENKGRVVSSNLGNLTVIPASHRDTATGWGIKGVTDSMGRPVVLSQPAAAQFMQMISDSKGQVTGADVASSGRSIKHNAKVGGHENSVHLYGEGLDVSGSTYKWMLKNGIKYGWKYKYSQGPGSGHYDYVGTGAGKTPILSSFGGKAFPFSTTTRTDSSGRPQVGVGGAADFGSILKSMNLSEMLEESFGRGGGPGSFMGGETMDVLGGMFGGGALPGSNDMFKSGRTKRNASTYEEQARVRRVTEQRNAARREINNRTTEIVQMALAAVESSNGSNRQFISRAEAGIRQLLGAQAGGGTFANVGGTTGTVLRTAVAVLNSFNNPLRGIFQ
Physico‐chemical
properties
protein length:498 AA
molecular weight:53304,4 Da
isoelectric point:9,65
hydropathy:-0,41
Representative Protein Details
Accession
3FVpv
Protein name
3FVpv
Sequence length
603 AA
Molecular weight
64497,85140 Da
Isoelectric point
9,38681
Sequence
MQGGFLEGFAKGGWISGPQSGYPVSLDGNKPDFIGHGTEYVARRSDGGAFVVPFDTPATRAMPGLTNSRLSEAAQQGFFFGGGGLDKFSRAMIKEHEGLRLKKYKDNLGFTSIGYGHLVQPGEKIPNEISKAYAEQLFNKDYKHHKRAAQGIPGYKNLSLQQKAAMIDLTFNMGPQWTNEFPLMMAALQKKDYNTAAAELKDSLYYNQVGRRGVTTVSLMNNNGVGDYLKVLGIVPPAGSDQNKQNFGFAPIFNMLLGAGPAGSEMDLMQKVIENKGRVTSSNLGNLAILPASHKDTATGWGIKGVTDSMGRPVVLSQPAAAQFMQMISDSKGQVNGADVASSGRSIKYNDKVGGHENSVHLYGEGLDVSGSTYKWMLKNGIKYGWKYKYSNGPNSGHFDYVGEGSGRTPILSPFKTGKSFLYSTKDITNAGGTSRPGVTVGGASDLSEIFKEFKFGDNLKDMFGGDTSNTSLMDLFGGGFQAGGMTNSGSLFGGGKPAFSKGQGSYEEQAKVRRVTEQRNQARREINAKTTEIVQMALAAVESSNGSNREFIQVAEAGIRQLLGAQAGGGTFANVQGTTGTVLRTAVAVLNSFNNPLRGIFT
Other Proteins in cluster: phalp2_3395
Total (incl. this protein): 11 Avg length: 555,3 Avg pI: 9,64
Protein ID Length (AA) pI
3FVpv 603 9,38681
1TaGw 557 9,85233
1g4oy 515 9,63604
2U8CA 579 9,90346
4uptF 572 9,60413
84C4I 522 9,67369
8ABfR 617 9,72759
8EwAu 530 9,24156
AmUv 565 9,70728
pdag 550 9,61464
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_21079
8LRzV
 133 27,7% 677 2.541E-50
2 phalp2_22754
8gQfh
 42 22,9% 722 1.453E-35
3 phalp2_26461
1WdvJ
 1 24,8% 620 5.730E-23

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Caudoviricetes sp
[NCBI] 		2832643 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LC629488 [NCBI]
CDS location
range 41692 -> 43188
strand -
CDS
TTGGATACACATACTATTGGATATGGTCATTTAGTTACACCTGATGAAAAAATACCTAATACAATTAGTAGGGCATTTGCTGAACAGTTATTTAACAAAGACTATAAACATCATAAACAAGCTGCTCAAGGAATACCTGGATATGACAATCTTTCATTGCAACAAAAAGCAGCAATGATTGATCTTACATTTAATATGGGTCCTGAATGGCATAAAGAGTTTCCATTAATGATGGCTGCTTTACAGAAGAAAGATTATAATACTGCTGCTGCAGAACTTAAAAATAGTCTTTATTATAATCAAGTTGGTCGTCGTGGTGTCACTACAGTATCTTTGATGAAGAATCAAGGTGTAGCTGATTATCTAAGGGTATTAAATATTATTCCTCCTGCTGGTTCTGATCAAAACAAACGAAATTTTGGTTTTGCACCTATCTTTAATATGCTTCTAGGTGCTCAACCTGCAGGTGCATCTGAAATAGATGGTTTCAATCAAAAAGTTCAAGAGAATAAAGGTAGAGTAGTATCATCTAATCTTGGAAATCTTACAGTCATTCCTGCAAGTCATAGAGATACTGCTACAGGATGGGGTATCAAGGGAGTCACTGATTCTATGGGTCGTCCTGTAGTCTTATCTCAACCTGCTGCTGCACAATTTATGCAAATGATATCAGACTCAAAAGGTCAGGTCACTGGTGCTGATGTGGCAAGTAGTGGTAGGAGTATCAAACATAATGCTAAAGTTGGTGGACATGAAAATTCAGTACATTTATATGGTGAAGGACTTGATGTTTCTGGTTCTACCTACAAGTGGATGTTGAAGAATGGTATTAAATATGGGTGGAAATACAAATATTCTCAAGGTCCTGGTAGTGGTCATTATGATTACGTTGGAACAGGTGCTGGTAAAACACCGATTCTTTCCTCCTTTGGTGGTAAAGCATTCCCATTCTCAACAACTACAAGGACAGATTCTAGTGGTCGTCCTCAAGTTGGTGTTGGTGGTGCTGCTGATTTTGGTTCTATTCTTAAAAGTATGAATCTAAGTGAAATGCTAGAAGAGTCATTTGGTAGAGGTGGCGGACCAGGTTCATTTATGGGTGGTGAAACAATGGATGTATTAGGAGGTATGTTTGGTGGTGGAGCACTACCTGGAAGCAATGATATGTTCAAGAGTGGTAGAACAAAAAGAAACGCATCTACTTACGAAGAACAAGCACGAGTTCGTAGAGTCACAGAGCAGCGTAATGCAGCAAGAAGAGAGATCAACAATAGAACTACTGAGATAGTGCAAATGGCATTAGCTGCTGTAGAATCTTCTAATGGATCTAATCGTCAATTTATTTCGAGAGCAGAAGCAGGTATTCGTCAACTTTTAGGTGCTCAAGCAGGTGGTGGAACATTTGCAAATGTAGGTGGAACAACAGGAACAGTTCTTAGAACTGCAGTAGCGGTGCTTAATTCCTTTAACAACCCTCTTAGAGGCATCTTCCAATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3FVpv) rather than this protein.
PDB ID
3FVpv
Method AlphaFoldv2
Resolution 63.77
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50