Protein

Protein accession
A0A866D1F8 [UniProt]
Representative
81fvs
Source
UniProt (cluster: phalp2_34008)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MSVKQKLVYCSVAAVLGTVATLHPGELRTSQDGLKLLAGYESCVRSSYTDTVGVPTCGIGHTKGVRMGMLASDATIAQWFVEDVLEAESCVNRYFGGQSMPQPVFDSVVSLVFNVGCYGTRWNSKRSAPTNIARYAVAGDWWGVCEHIADFRYAGGKVSPGLENRRREEQKHCIRYR
Physico‐chemical
properties
protein length:177 AA
molecular weight:19462,0 Da
isoelectric point:8,69
hydropathy:-0,17
Representative Protein Details
Accession
81fvs
Protein name
81fvs
Sequence length
266 AA
Molecular weight
29565,26720 Da
Isoelectric point
9,04255
Sequence
MKTSNRGIDLITEFEGLRLNSYQCSAKVWTIGYGHTKGVKQGMSCNIAQAISWLKEDLSKSEKNVMKFDTIYNFTQNEFDALVSFAFNVGSIDQLVNGGKRSKGEIADSIMKYNKANGQIIGGLVRRRRLERDLFLGNNLPTVSYSGHIQSIGDTPFYSNGQTCGSVGMGLRLEALKIKCDKGGITYQAHIQDIGWQEQKKDGELCGSVGKSKRLEAIKISYYGQGSLKYRVHIQDIGWQEWKSDGEISGTVGQGKRIEAIEIKID
Other Proteins in cluster: phalp2_34008
Total (incl. this protein): 10 Avg length: 207,7 Avg pI: 8,13
Protein ID Length (AA) pI
81fvs 266 9,04255
4y74w 283 4,97912
81MgX 285 6,53986
A0A2S1PFQ6 179 8,83734
A0A866D199 177 8,47542
A0A866D1F3 177 8,69396
A0A866D1V0 177 8,69396
A0A866D235 177 8,69396
A0AB74UQ76 179 8,68475
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_10187
xiY3
 70 48,1% 162 2.911E-57
2 phalp2_21403
41rlL
 6 39,5% 162 2.709E-48
3 phalp2_23419
6k2xA
 3 38,2% 183 1.342E-37

Domains

Domains [InterPro]
GH24
ChW
Representative sequence (used for alignment): 81fvs (266 AA)
Member sequence: A0A866D1F8 (177 AA)
1 266 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959, PF07538

Taxonomy

  Name Taxonomy ID Lineage
Phage Aeromonas phage Atoyac13
[NCBI] 		2767549 Autographiviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MT682388 [NCBI]
CDS location
range 20428 -> 20961
strand +
CDS
ATGTCTGTGAAGCAGAAGCTGGTCTACTGCTCTGTGGCTGCTGTGCTGGGCACTGTGGCTACACTTCACCCCGGGGAGCTGCGTACCTCGCAGGATGGCCTAAAGCTACTCGCCGGGTATGAGTCCTGCGTCCGCTCCAGCTACACCGACACTGTAGGCGTCCCTACGTGCGGCATAGGGCACACCAAAGGCGTCCGAATGGGTATGCTTGCCTCGGACGCTACAATCGCACAGTGGTTCGTAGAGGACGTCCTAGAGGCGGAATCCTGCGTGAACCGATACTTCGGCGGGCAGTCCATGCCGCAGCCGGTATTCGACAGTGTAGTGTCGCTGGTGTTCAACGTGGGCTGCTACGGCACCCGGTGGAACAGCAAGCGGTCGGCACCTACCAACATCGCCCGATACGCTGTGGCCGGTGACTGGTGGGGAGTGTGTGAGCATATCGCTGACTTCCGGTATGCCGGTGGCAAGGTGTCACCCGGACTGGAGAATCGGCGTAGAGAGGAGCAGAAGCATTGTATCAGGTATCGCTAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (81fvs) rather than this protein.
PDB ID
81fvs
Method AlphaFoldv2
Resolution 95.94
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50