Protein

Protein accession
A0A7D5JWD6 [UniProt]
Representative
1LNa3
Source
UniProt (cluster: phalp2_25165)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNDNQRGALLSFAYNLGAHFYGSAGFSTISRVLREKEWNKVPDALYLYRNPGTSVEAGLTRRRIAEGDLWKS
Physico‐chemical
properties
protein length:72 AA
molecular weight:8137,0 Da
isoelectric point:9,59
hydropathy:-0,51
Representative Protein Details
Accession
1LNa3
Protein name
1LNa3
Sequence length
72 AA
Molecular weight
8172,23240 Da
Isoelectric point
9,81829
Sequence
MTDNQKGALLSFAYNLGAGFYGSSDFNTITRVLKNKEWVKVPDALYLYRNPGSNVELGLSRRRMAEGNLWKK
Other Proteins in cluster: phalp2_25165
Total (incl. this protein): 124 Avg length: 86,5 Avg pI: 9,59
Protein ID Length (AA) pI
1LNa3 72 9,81829
1597o 76 9,57125
15bPY 79 9,62747
15ee0 106 9,58711
15kZ4 75 9,57009
15nWc 79 9,52090
1601e 77 9,57131
162Sn 62 9,52084
163il 106 9,07168
164Bs 79 9,62747
16o5O 72 9,84073
16ocj 79 10,22625
19Eqk 83 9,92976
1PLK9 84 9,85220
1PQcL 99 9,10276
1aqAp 72 9,75144
1armE 57 9,89624
1ikJG 55 9,22802
1wUIr 95 9,51961
1zDlr 60 9,69613
26SRe 85 9,81655
27Hdc 70 9,91364
27Sje 92 9,51626
27wKT 60 9,99223
29Pfz 90 9,80920
2IlqN 73 10,97486
2KGTz 72 9,98372
2ixlQ 72 10,08313
329RK 95 9,51961
32c87 113 9,36315
3PkFn 84 9,84730
3UxGh 81 9,84730
3XFB6 78 9,58086
3cXOx 102 9,26167
46Bak 153 9,38365
46Pfu 74 9,39738
475BF 80 10,20330
48h8x 73 10,07642
49xim 72 10,26100
4AcKH 72 9,86439
4BZoF 64 9,66583
4ClOm 108 9,47339
4DKkP 73 9,81713
4DVcR 94 10,32998
4YA3c 72 9,80127
4Yzdv 72 9,98772
4ml6F 88 10,13258
4nzYP 136 8,16262
4oMtN 73 9,91326
4qf0S 72 10,14199
4qqvC 53 10,59108
4vLJZ 73 10,25584
50RqN 99 9,30093
50X4z 103 9,47551
52GZa 73 10,07642
52MoL 107 7,82267
54SOY 136 9,79850
54l6L 64 9,62914
551aS 103 9,64397
55Vem 95 9,92351
565cY 73 9,75150
57hSc 95 9,52032
592tN 108 9,47339
5ANpe 94 9,91248
5ByhY 108 9,56577
5Cubt 64 9,62914
5Dcc6 118 9,43290
5Iakk 72 10,59088
5ac3v 95 9,69361
5c5qT 106 9,34335
5dabL 72 9,66408
5f78D 53 10,59108
5hncP 95 9,64410
5hwNM 122 9,55139
5iJsd 95 9,84524
5kqmP 103 9,33588
5kuCb 136 9,43393
5lpZd 149 9,05757
5luCe 73 9,99010
5mlv4 136 9,25942
5uTnW 72 9,98378
5uYCs 73 9,81707
6GMm8 107 8,08951
6GdTN 72 9,24826
6L2y1 72 9,80127
6L3EJ 72 9,80263
6LPWC 73 9,84885
6Llwk 106 9,74873
6MFq1 73 9,91326
6MHBG 107 7,82467
6MLfa 149 9,05782
6McAe 106 10,05212
6Mx8G 64 9,69406
6UALG 63 9,62805
6X3tr 104 7,91648
6ztge 136 9,56841
7JX4A 72 9,51452
7L7hY 95 9,51839
7Qnbw 114 6,73613
7nY0u 90 8,00718
8I3Dt 72 9,59452
8jFZn 78 9,91454
8rCW7 72 10,20388
AT2T 72 9,84073
C8uO 136 9,69593
FOz6 107 5,02692
Fg16 94 9,05595
GGsl 72 9,62811
GJEi 72 9,99171
Gob9 72 10,35222
Gpi5 77 9,62837
IKBh 72 9,51458
INBW 100 9,39738
Jhdk 67 9,62914
Kpiv 67 9,62914
L5Ni 77 9,57131
LTTN 67 9,62914
bSOG 73 9,98681
bXGz 74 9,57628
h2JN 78 9,58086
heg5 79 9,57131
iyhY 106 10,13258
jQNb 69 9,99049
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13104
8kSiJ
 1 34,2% 70 3.345E-06
2 phalp2_9510
12ud4
 2 39,3% 66 4.602E-06
3 phalp2_7764
77796
 37 36,1% 72 6.333E-06
4 phalp2_37101
1bvx6
 877 38,5% 70 1.543E-04
5 phalp2_15074
7BwGK
 4 34,8% 66 2.124E-04
6 phalp2_24173
2nDwl
 15 34,7% 69 4.023E-04
7 phalp2_39267
4724r
 247 34,7% 72 4.023E-04

Domains

Domains [InterPro]
GH24
Representative sequence (used for alignment): 1LNa3 (72 AA)
Member sequence: A0A7D5JWD6 (72 AA)
1 72 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Synechococcus phage S-CAM7
[NCBI] 		1883368 Kyanoviridae > Mazuvirus > Mazuvirus scam7
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MT586120 [NCBI]
CDS location
range 158149 -> 158367
strand +
CDS
ATGAACGACAACCAGAGAGGAGCTTTGTTGAGCTTCGCATATAATCTGGGAGCACATTTCTATGGTAGTGCTGGTTTCAGCACAATAAGCCGTGTTCTTCGGGAAAAGGAGTGGAATAAAGTCCCTGATGCGCTATACTTATACCGAAACCCAGGCACAAGCGTAGAGGCAGGCTTGACCCGCAGACGCATTGCCGAAGGTGATCTTTGGAAATCTTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1LNa3) rather than this protein.
PDB ID
1LNa3
Method AlphaFoldv2
Resolution 98.15
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50