Protein

Protein accession
A0A6J5RSI8 [UniProt]
Representative
2YvPg
Source
UniProt (cluster: phalp2_30084)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MSINLDAAVGLCKTFEGFRSSPYLCPAQKWTIGYGCTFYSTGQRVTATDPVVSVERAEEMLIAELRSNCLPSALRLCPILDLHEKKLNAVVDFVFNLGADRLRSSTLRRKINSKDWTGSKAELARWVYGGGKVLPGLVKRRAAEAALFD
Physico‐chemical
properties
protein length:149 AA
molecular weight:16456,9 Da
isoelectric point:9,22
hydropathy:-0,06
Representative Protein Details
Accession
2YvPg
Protein name
2YvPg
Sequence length
389 AA
Molecular weight
40505,93580 Da
Isoelectric point
9,61548
Sequence
MARKTSQVGVDLIKEFEGLRLTAYQDSVGVWTIGYGHTNNTASADKYPVYAGQTISKAKAETILKADLITFENAVNNYVTVSINQNQFDALVSFSFNLGAGALRTSTLLQKLNNGDVNGAANEFGRWVNAGGVQLPGLVRRREAEKQLFLSGSTGGGGNGGNGGGSGGGSTDTYVVKSGDTLSGIAVKFGVTVSQLKKWNNISNADSIQIGQKLIVKEPSGGGGSGGSQKTYTVKSGDTLSGIAVKFGVTVSQLKKWNNISNADSIQIGQKLTVKEPSGGSGGSGGGSTETYTVKSGDTLSGIAVKFGVTTAQLQKWNNISNADSLQIGQKLIVKEPVGGSQTTYTVKSGDTLSGIAVKFNVTVSNLMKWNNISNADTIKIGQKLIIKN
Other Proteins in cluster: phalp2_30084
Total (incl. this protein): 3 Avg length: 230,7 Avg pI: 7,93
Protein ID Length (AA) pI
2YvPg 389 9,61548
A0A218M2W9 154 4,94104
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1915
4hcut
 54 48,6% 288 1.372E-59

Domains

Domains [InterPro]
GH24
LysM
LysM
LysM
LysM
Representative sequence (used for alignment): 2YvPg (389 AA)
Member sequence: A0A6J5RSI8 (149 AA)
1 389 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959, PF01476

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR797253 [NCBI]
CDS location
range 32648 -> 33097
strand -
CDS
ATGTCCATAAACCTAGATGCGGCTGTTGGGCTCTGCAAGACCTTCGAGGGGTTCCGCTCCAGCCCATATCTTTGCCCTGCACAAAAATGGACCATCGGATACGGCTGTACGTTTTACTCAACGGGGCAGCGAGTAACGGCAACAGATCCGGTCGTTTCTGTTGAAAGAGCAGAAGAAATGCTTATCGCTGAGCTCCGCTCTAACTGCCTTCCGTCTGCTTTACGTTTGTGTCCAATTCTTGATTTGCATGAGAAAAAACTTAATGCCGTGGTGGACTTTGTATTTAATTTAGGCGCTGACCGCCTACGGTCATCCACGTTGCGGCGTAAAATAAACAGCAAAGATTGGACTGGTTCAAAGGCTGAGCTTGCTCGCTGGGTTTACGGCGGCGGCAAGGTTTTACCTGGCCTCGTTAAGAGGCGCGCTGCTGAAGCGGCGCTTTTTGACTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2YvPg) rather than this protein.
PDB ID
2YvPg
Method AlphaFoldv2
Resolution 79.75
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50