Protein

Protein accession
A0A6J5P5R3 [UniProt]
Representative
4CJ0A
Source
UniProt (cluster: phalp2_30334)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSNVKVFTGGPRKINQAGIDLIKKFEGLKLKAYLCPANVWTVGYGSTGEHVSPSTVLPNEAAAHILLLRDLVRFERAVQQSVIVPLTDNQFAALVSFTFNLGEGALRRSSLLRLLNSGDYNAVPTELMKWVRAGGKVLQGLVNRRQAEADLWRSQDGNSSVSN
Physico‐chemical
properties
protein length:163 AA
molecular weight:17823,2 Da
isoelectric point:9,77
hydropathy:-0,09
Representative Protein Details
Accession
4CJ0A
Protein name
4CJ0A
Sequence length
207 AA
Molecular weight
22330,21500 Da
Isoelectric point
4,86459
Sequence
MTITLAQAEDMLRAEVERFEKAVNRLVEVPLSQNQFDALVSFAYNVGDGALARSTLLRLLNQGDYDAVPGQLARWTHGGGRVLPGLVKRRRMEGELWMSPAAQIYEIEEPMAQDVTEEPVGSNVMLEMIIGLARHLVTGAGGLTAASSGGDASAPATWLGLTIFVAGVAMSVFDKIKREGDASILNVVRESIDAIHDRLDEKDGPKA
Other Proteins in cluster: phalp2_30334
Total (incl. this protein): 8 Avg length: 170,0 Avg pI: 8,82
Protein ID Length (AA) pI
4CJ0A 207 4,86459
B5BTX9 165 9,56861
A0A2K9VI88 165 8,92857
A0A9E7QXY8 165 9,35051
A0A9E7QYB1 165 9,35051
A0A9E8G7G4 165 9,35051
A0AAF0CXD4 165 9,35051
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13857
7s4x2
 6 44,2% 140 2.028E-26
2 phalp2_14618
5vvs4
 11 40,2% 154 2.390E-20
3 phalp2_4127
1EJtW
 7 34,6% 205 8.243E-20

Domains

Domains [InterPro]
GH24
Disordered region
Representative sequence (used for alignment): 4CJ0A (207 AA)
Member sequence: A0A6J5P5R3 (163 AA)
1 207 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796765 [NCBI]
CDS location
range 15158 -> 15649
strand -
CDS
ATGAGTAATGTTAAGGTTTTCACGGGCGGCCCCCGAAAGATTAACCAAGCGGGCATTGACCTAATCAAGAAGTTTGAGGGTCTAAAACTCAAAGCCTACCTATGCCCTGCGAATGTTTGGACTGTCGGGTATGGCTCGACGGGTGAACACGTTAGCCCCTCTACAGTGCTTCCTAACGAGGCTGCGGCCCATATCCTGCTATTAAGGGATTTGGTCAGGTTTGAGCGGGCGGTGCAACAATCCGTCATTGTTCCCTTAACGGATAACCAATTTGCTGCTTTGGTTAGCTTTACCTTTAACCTCGGTGAGGGCGCGTTAAGGCGGTCTAGCTTGCTGAGACTTCTTAACTCGGGGGATTACAACGCAGTTCCCACTGAGTTAATGAAATGGGTTCGCGCTGGTGGTAAGGTATTACAAGGCTTGGTTAATCGTCGCCAAGCCGAGGCTGATTTGTGGAGGTCACAAGATGGCAATTCTTCGGTTTCTAACTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4CJ0A) rather than this protein.
PDB ID
4CJ0A
Method AlphaFoldv2
Resolution 73.77
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50