Protein

Protein accession
A0A6J5N9Y7 [UniProt]
Representative
6wSxJ
Source
UniProt (cluster: phalp2_9153)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MIKGIDISRWQGLINWPMVSKNVDFAFIKIGGSDDGFYPDGQAVRNAIEARANGVPVGFYVYLGGAFNISDEVAHIKNLISNIGGLRQNEVLALDWEERHPNEVEYVAGIAKSLVDAGIKAPLIYMSLSRVRGNNWQRLVDLNCGLWVAAWGNNDDVADATPPSDEWPMWAVWQYSSTGSIPGISGRVDLDLFQGTVDQFKQYGQGRTVTLPAPTVGSKVVFASGSVEYSVAPGESLSVIAAKFGKSWQELWALNRDRVSQPDKIFPGQKLRVWSELNPPLPTPAPIAPPENPNVRYYDVVNGDNLSNIAAKFALPNYIVLYEANKDLIGPNPDLIRPGQRLRIP
Physico‐chemical
properties
protein length:345 AA
molecular weight:37931,5 Da
isoelectric point:5,24
hydropathy:-0,19
Representative Protein Details
Accession
6wSxJ
Protein name
6wSxJ
Sequence length
345 AA
Molecular weight
38109,53790 Da
Isoelectric point
5,89792
Sequence
MRVIDVSRHQQFINWPFVAANIQAAMIKIGGSDDGLYTDSKAVTNAIGARSAGMAVGFYYFLGGVHTIAEEVQQIKNSINEIGGLRPGEPFALDWEKRRAGHDEVGYLTAIVEALIRGGMPSPFIYMNLNYVRTQNWINLVNRGCPLWVAAWGDNDDIPETQEIPSSDEWKQWDMWQYTSISNVPGIAGRVDQNEFRGDVERFKTFGGRSGLSVPESVNVATPIPPQNNITEYTVIAGDTLSGIAPRYGVSWQQLYALNRDRISNPNKIYVGQKLRTPGASMAPATQPQHPAPAPHEHIVQNGENLSVIAAKYGLPSWQTLYDLNAAIIGNDPNLIKPGQRLRLP
Other Proteins in cluster: phalp2_9153
Total (incl. this protein): 7 Avg length: 339,6 Avg pI: 6,22
Protein ID Length (AA) pI
6wSxJ 345 5,89792
18We3 327 6,42857
1lpwy 346 8,91174
4foPg 344 5,71098
7YkkP 327 5,81999
87o1c 343 5,55996
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_30061
2NCcc
 23 31,7% 233 3.657E-49
2 phalp2_9283
7cTgF
 101 34,5% 356 1.719E-48
3 phalp2_17042
7nSW4
 41 32,0% 356 3.902E-45
4 phalp2_37809
4Ez2v
 8 29,5% 227 2.486E-44
5 phalp2_39009
8i5mw
 7 26,6% 229 3.988E-43
6 phalp2_22096
5ZSom
 2292 26,3% 383 1.862E-42
7 phalp2_32821
2L8bh
 41 26,0% 242 1.387E-38
8 phalp2_4299
7ZuoI
 1 29,6% 233 4.733E-38
9 phalp2_39912
1jXPT
 300 31,8% 220 1.101E-31
10 phalp2_26548
858CP
 728 26,4% 355 2.741E-31

Domains

Domains [InterPro]
GH25
LysM
LysM
Representative sequence (used for alignment): 6wSxJ (345 AA)
Member sequence: A0A6J5N9Y7 (345 AA)
1 345 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01476

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796629 [NCBI]
CDS location
range 3713 -> 4750
strand -
CDS
ATGATAAAGGGTATAGATATTTCTCGTTGGCAAGGGCTTATAAATTGGCCAATGGTTTCTAAAAATGTTGATTTTGCGTTTATAAAAATTGGTGGATCCGACGACGGATTTTATCCGGACGGTCAGGCCGTTAGAAACGCTATTGAAGCACGTGCAAATGGCGTGCCTGTTGGATTTTATGTATATCTTGGCGGCGCATTCAATATCTCAGATGAAGTCGCCCATATCAAAAACTTGATTAGTAATATTGGCGGCCTGAGACAGAATGAAGTGCTTGCTTTGGATTGGGAGGAACGTCACCCAAATGAAGTCGAGTATGTCGCCGGCATTGCAAAATCACTAGTTGACGCAGGTATTAAAGCTCCATTGATTTATATGTCATTGTCGCGTGTACGTGGCAACAATTGGCAGCGTCTTGTTGATCTTAATTGTGGCCTTTGGGTTGCAGCGTGGGGAAATAACGATGATGTAGCTGATGCTACTCCACCTAGCGATGAATGGCCTATGTGGGCTGTTTGGCAATATAGTTCGACTGGAAGTATACCCGGTATTTCTGGCCGCGTTGATCTTGATTTGTTTCAGGGTACAGTTGATCAATTTAAGCAATATGGTCAAGGCCGCACCGTTACGCTTCCGGCTCCTACGGTTGGATCTAAAGTTGTATTTGCTTCAGGATCGGTTGAGTATTCTGTTGCGCCAGGCGAAAGTCTGAGTGTTATTGCTGCAAAATTTGGTAAGTCTTGGCAAGAGCTTTGGGCATTAAATCGTGATCGTGTTTCTCAGCCGGATAAGATTTTCCCCGGCCAAAAGCTTCGTGTTTGGTCTGAGCTTAACCCACCGCTACCCACTCCAGCACCAATTGCACCGCCTGAAAACCCTAATGTCAGATATTATGATGTCGTCAATGGCGATAATCTCAGTAATATTGCTGCTAAGTTTGCATTACCGAACTATATTGTGCTCTATGAAGCTAACAAAGATTTGATTGGCCCTAATCCTGATTTGATACGACCAGGCCAGCGGCTTAGGATTCCATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6wSxJ) rather than this protein.
PDB ID
6wSxJ
Method AlphaFoldv2
Resolution 80.39
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50