Protein

Protein accession
A0A6J5MD67 [UniProt]
Representative
6Mntu
Source
UniProt (cluster: phalp2_35257)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVKQSTKTTNMISKKAIELIIKHEVGGRAVYEKRYQKPIWAGGDSGVTIGLGYDCGYVTEKQFFSDWDGLNLNFIHALRKVVGIKGEAVKTMLRGEILQVRIPYNFAYDVFVNKSLPKYYALTKAIYPYLDTLNEDTRGALVSMIYNRGNKLDGDRRKEMRAIVELVAKADYEGIADQIERSKRLWENGLDGLVKRREEEADLILNSLT
Physico‐chemical
properties
protein length:209 AA
molecular weight:23819,2 Da
isoelectric point:9,10
hydropathy:-0,37
Representative Protein Details
Accession
6Mntu
Protein name
6Mntu
Sequence length
199 AA
Molecular weight
22644,00550 Da
Isoelectric point
6,62017
Sequence
MISKKAIDLIVQFEVGGKSYYDKVLHRPNFPGYGGIKIGIGYNLAYTYQKQIINDWSGNINPNYFPALFRVLGLKGIPAKQMLIGDLLKVTIPYLNAYDVLVKRTIPRYYLMALEIYPELSLLNEDTKGAIVSMVMCRGIKLEGENRAEMRELVDLIADQDYEGIADAVERSKRLNEARGFDDLVRRREAEADLIFNSI
Other Proteins in cluster: phalp2_35257
Total (incl. this protein): 167 Avg length: 201,7 Avg pI: 8,18
Protein ID Length (AA) pI
6Mntu 199 6,62017
12XQ5 200 8,37014
1940d 201 7,69358
19NKm 202 8,63014
19Vt0 200 8,31315
1Cx8Z 200 9,12584
1JTiM 198 6,00614
1JXm8 201 8,48573
1JZil 200 8,96260
1K16D 200 7,72308
1K45f 200 8,94913
1K66n 200 8,47148
1K9KC 192 8,61183
1KkMw 199 7,84240
1LHGU 214 9,01856
1LUyi 201 7,80320
1LgCn 201 9,09573
1Lzho 201 8,90400
1MJUS 199 8,38181
1Mp4P 201 8,56464
1Mp5B 202 7,80385
1Mzpi 200 8,38000
1YA4H 200 5,61100
1ZYnW 200 5,61111
1aDRw 213 9,08148
1dSKn 200 8,47136
1etRn 242 9,82287
1eufx 200 8,79054
25NDB 200 8,23830
284GZ 200 9,14150
284bL 213 8,77139
2R7dc 200 8,23830
2YA9p 201 8,57992
2YSsS 230 9,57054
305Gq 201 8,49766
31Gsj 194 5,33112
31vhO 200 8,29645
33WhJ 200 8,79054
33zKs 199 5,79504
36Uf 200 5,20517
38jAs 213 9,09760
3ToQu 200 8,94913
3UgBV 200 8,93585
3VWWE 213 9,12758
41NL1 200 8,39032
45U6m 201 8,47161
45VWI 195 5,56865
46ZCo 201 6,75846
46ny5 212 8,79151
479p4 201 5,96340
48g5A 201 7,81313
49SYp 200 9,03823
49a1a 201 8,87164
49cEH 200 8,45917
4A5CS 192 8,47155
4A8K0 200 8,94913
4DacM 200 8,79054
4DegE 200 8,79054
4GddC 199 5,95493
4GktZ 204 6,62580
4INm5 201 8,82019
4V6QJ 213 8,97679
4Vaou 201 8,48573
4a2II 200 9,24614
4bLCB 194 5,95431
4bqpi 192 9,02353
4bvwp 208 8,88737
4g85R 199 8,75089
4glDD 200 8,77674
4glRS 202 8,39051
4jLhG 210 4,89136
4m3e9 200 8,77674
4nfRH 213 9,11211
4ogM0 192 8,47155
4qKFK 200 8,47148
4rvRy 213 9,08329
4wq4C 200 8,79054
50HwW 198 8,61267
51Ssn 199 5,35403
52Bzw 200 9,11056
52y49 192 7,72274
53kmj 200 8,79054
55CB8 209 9,09605
55P0b 201 8,88814
57U8Q 200 8,79054
58BUM 200 6,00364
58JnF 200 8,79054
58MV8 161 7,74848
58OeL 201 8,37207
5AFiL 210 9,09592
5AHol 200 8,88698
5CsOt 199 6,62529
5DsnI 200 8,47148
5aIBv 200 8,47142
5aRoi 195 9,12784
5alv7 210 9,19946
5avI5 199 6,16984
5avtI 209 9,21435
5c1F5 199 6,17512
5eezL 200 8,94919
5jFfq 192 7,72313
5kM6B 201 8,48586
5kX4i 200 6,62745
5lTx6 200 9,11069
5mCaa 198 8,62866
5mJNY 200 8,47148
5n2kU 200 8,38007
5n5Be 200 5,99875
5nUEt 201 8,59559
5necd 201 8,59559
5u8qu 201 8,47181
5uEHL 214 8,91013
5uarZ 199 5,95442
5vHn2 210 9,19959
5vOQk 200 8,88498
5w6vc 201 8,87132
5wvir 201 8,37201
5xl2B 200 8,47148
5zBUF 213 9,09580
5zBhH 198 7,82545
6Aeva 199 6,17154
6Gli5 200 8,89730
6GmZh 200 8,69132
6H0fH 200 8,89717
6KUIR 200 9,11069
6KYHy 200 8,94913
6L7di 200 8,88473
6LCTd 200 9,02501
6MlAw 199 9,19359
6yVtc 200 8,79034
6yp4E 201 8,88737
7FRwH 200 5,20517
7Kbdf 201 8,59668
7L6Ej 201 8,47181
7LNyE 200 5,97966
7X5cp 210 9,28192
7XFQm 200 8,93585
7XeTJ 201 8,87280
7XfcH 200 8,99187
7Xfsw 200 8,76365
806mA 192 8,38181
80RFx 200 8,73838
81Vkk 200 8,45917
82Azp 269 8,79157
82OMr 210 9,26586
83F2g 201 7,70995
83Fr2 200 8,93572
83dfE 201 7,69921
84Eml 202 8,52712
87nRh 201 7,66630
87r1Z 200 8,75102
89k9V 201 7,80720
8mTpF 199 7,72257
8mzjf 199 5,97715
8oA6n 200 8,47142
8oErH 200 8,45917
8sah9 199 5,95493
8srT5 201 7,62793
GU5r 200 8,96273
GfpB 200 8,79054
TOeO 199 6,17495
U7HW 200 8,37008
iTPs 200 8,93585
m7io 200 5,61100
A0A6J5MBE1 199 8,70512
A0A6J7WNZ8 199 6,62603
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_22061
5D403
 92 56,0% 141 2.544E-77
2 phalp2_10617
2jW9y
 699 43,5% 202 5.948E-76
3 phalp2_36119
6KcGh
 69 37,2% 161 2.983E-56
4 phalp2_39316
4mrm5
 85 34,3% 201 1.812E-51
5 phalp2_18109
49DxQ
 12 31,1% 196 1.359E-42
6 phalp2_16489
6PYCY
 13 26,9% 197 5.132E-31
7 phalp2_39402
4QzwI
 8 25,6% 179 1.375E-20

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 6Mntu (199 AA)
Member sequence: A0A6J5MD67 (209 AA)
1 199 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796396 [NCBI]
CDS location
range 14227 -> 14856
strand +
CDS
ATGGTAAAACAATCTACCAAAACTACTAATATGATCTCCAAGAAAGCTATTGAACTAATAATCAAACACGAGGTAGGTGGTAGAGCTGTTTATGAAAAACGTTACCAAAAGCCTATTTGGGCGGGTGGCGATAGCGGAGTTACCATCGGACTTGGGTACGATTGCGGTTATGTAACCGAGAAGCAGTTCTTTAGCGATTGGGATGGCTTAAATTTAAACTTTATTCACGCATTAAGGAAAGTGGTAGGGATTAAAGGAGAGGCGGTTAAAACGATGCTTAGAGGGGAAATTCTACAAGTTAGAATACCATACAATTTTGCATACGATGTTTTCGTTAATAAGTCATTACCTAAGTACTATGCTTTAACTAAAGCAATTTACCCATACTTAGATACTTTAAACGAGGACACAAGGGGTGCTTTGGTTTCAATGATTTACAATAGGGGTAACAAGTTGGATGGCGATAGGAGAAAGGAAATGAGGGCAATAGTTGAATTAGTCGCTAAAGCAGATTACGAAGGGATTGCCGACCAAATAGAACGAAGCAAAAGATTATGGGAAAATGGGTTGGATGGCTTGGTCAAACGTAGAGAAGAAGAAGCGGACTTGATACTAAACTCACTAACCTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6Mntu) rather than this protein.
PDB ID
6Mntu
Method AlphaFoldv2
Resolution 96.92
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50