Protein

Protein accession
A0A6J5L9T4 [UniProt]
Representative
2YvbE
Source
UniProt (cluster: phalp2_1787)
Protein name
Lysozyme
Lysin probability
92%
PhaLP type
endolysin
Probability: 81% (predicted by ML model)
Protein sequence
MRNLLTEVSKIKNMMGLNSNINEQSFFDDVNKIVGVKPSNQEPNFMDKWSSMAPPKDQMVPNSGGVFDDINKILKPTKSKTSQKPTGVSDKLVNFVGNIEFFVPCVYDDDKGGKCVRGEVDCCLKGRTPSGTPTIGYGTVYYPDGRKVTPKDPSITKDKAKVYLKTNLDKLANNLLNLYPNLNQNQVDALSSLCYQVGFAGCTTNAPKLSNSLKTNPNSLNGVKSNFLDFTHPDRRQKEWKIYSQGIYS
Physico‐chemical
properties
protein length:249 AA
molecular weight:27651,2 Da
isoelectric point:9,15
hydropathy:-0,61
Representative Protein Details
Accession
2YvbE
Protein name
2YvbE
Sequence length
225 AA
Molecular weight
25548,21610 Da
Isoelectric point
8,59778
Sequence
VVGSWFMINVPIWMESISSVLGVASTAIGLVVLFYTARSVIIKSRLDALKLKERSVAFDEKMKEKEDKMNEKISPALHFPSMQAVELIKEMESFRAKPYIDAAGVATIGYGTTVYPNGDSVSMKDRPISREEATMYLKLHASEDAYKIFEEFPSLNQNQLDALVSFVYNVGFEAFRKSTMFRIMKEDINDERIANEFSRWNKGGGKVLGGLVKRRNKEKDLYFLS
Other Proteins in cluster: phalp2_1787
Total (incl. this protein): 2 Avg length: 237,0 Avg pI: 8,88
Protein ID Length (AA) pI
2YvbE 225 8,59778
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_4451
31DIk
 4919 51,7% 145 4.971E-39
2 phalp2_34911
4lF8s
 21 48,0% 154 2.585E-36
3 phalp2_9745
82S7v
 113 43,7% 144 1.431E-26
4 phalp2_20664
7DMXE
 3 42,7% 145 1.256E-25
5 phalp2_28113
7zmZV
 50 47,6% 147 1.256E-25
6 phalp2_2632
6RhYr
 14867 45,8% 144 4.342E-25
7 phalp2_22738
7ZWXa
 59 41,2% 155 1.499E-24
8 phalp2_126
5jCCA
 637 46,3% 138 2.786E-24
9 phalp2_6830
8n5Jv
 121 46,3% 151 1.310E-23
10 phalp2_25823
58A15
 6 38,1% 152 8.375E-23

Domains

Domains [InterPro]
Unannotated
GH24
Representative sequence (used for alignment): 2YvbE (225 AA)
Member sequence: A0A6J5L9T4 (249 AA)
1 225 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796235 [NCBI]
CDS location
range 229298 -> 230047
strand +
CDS
ATGAGGAATTTATTGACTGAAGTTAGTAAGATAAAAAATATGATGGGTTTAAACTCAAATATTAATGAGCAATCATTTTTTGATGACGTTAATAAAATCGTAGGTGTAAAACCGTCAAATCAAGAACCTAATTTTATGGATAAATGGTCTTCCATGGCCCCACCAAAAGACCAAATGGTACCAAATTCGGGAGGTGTTTTTGATGATATAAATAAAATATTAAAACCAACCAAATCAAAAACAAGTCAAAAACCTACAGGTGTTTCTGACAAACTTGTAAATTTTGTTGGTAATATTGAGTTTTTTGTTCCTTGTGTTTACGATGATGATAAAGGTGGTAAATGTGTTAGAGGTGAGGTTGATTGTTGTTTAAAAGGTAGAACACCATCAGGAACCCCAACAATTGGTTATGGTACAGTTTATTACCCTGATGGTAGAAAAGTAACTCCTAAAGACCCATCAATAACAAAAGATAAAGCTAAAGTATATTTAAAAACAAACTTAGATAAATTAGCAAATAATTTATTAAACTTATATCCTAATTTAAATCAAAATCAAGTTGACGCATTATCTTCATTATGTTACCAAGTTGGGTTCGCAGGTTGTACAACTAATGCTCCAAAATTAAGTAATTCTTTAAAAACTAATCCAAATTCTTTGAATGGTGTTAAATCTAACTTTTTAGATTTTACTCATCCTGACAGAAGACAAAAAGAATGGAAAATTTATAGTCAAGGAATTTATTCTTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2YvbE) rather than this protein.
PDB ID
2YvbE
Method AlphaFoldv2
Resolution 89.42
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50