Protein

Protein accession
A0A6J5L0Y5 [UniProt]
Representative
6RxcX
Source
UniProt (cluster: phalp2_22190)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 95% (predicted by ML model)
Protein sequence
MNVVEMLKREEGVRACVYQDTLGLWTIGCGRLVDPSKPGAGLRPREIDMLLANDISDREQALRLSLPWFDTLDEVRQAVLVGMAFQLGTSSLMGFTNTLNFVRAGRWPEAATAMLASKWAQQTPARAQRMADMMRTGTWTQ
Physico‐chemical
properties
protein length:141 AA
molecular weight:15762,1 Da
isoelectric point:7,79
hydropathy:-0,17
Representative Protein Details
Accession
6RxcX
Protein name
6RxcX
Sequence length
215 AA
Molecular weight
22688,12360 Da
Isoelectric point
9,29494
Sequence
MTFLDRLFAFLGLGREAPAAGTAQAPAALVPVPGVYHPGQVVPVYGVGEVPPAPANTSIPKEAPVATTDPVAALTDLLIVEEGLRLTVYDDATGKAIGRGTQVVGHPTIGIGRALNRKGITASEARYLLANDVVEVREQVAKALPWSTRLTPVRRMVLEAMAFQMGIAGLMAFKNTLAMVERGDYAGAASGMLNSLWAKQTPARAKRMADLMREG
Other Proteins in cluster: phalp2_22190
Total (incl. this protein): 29 Avg length: 167,9 Avg pI: 7,07
Protein ID Length (AA) pI
6RxcX 215 9,29494
1l5Yz 144 5,35374
1qRQl 157 5,64675
2dier 184 8,56761
3JWMs 154 4,63325
3LMBT 156 5,03420
3fG6c 156 4,44148
40q0X 157 9,76105
4Egju 158 5,33453
4HJI2 199 9,02437
4HKOH 199 8,83650
4HPN0 192 9,13364
4Nb9f 197 9,59194
4Rnxq 157 4,74352
4f5Xg 199 9,55217
4f5jP 198 9,45063
5GNlR 156 5,67420
5Ja53 148 7,90842
5JrZ3 161 7,97269
5yUPq 188 4,45330
5z0vY 157 5,25439
6K8uh 169 5,58252
6XBa9 157 4,53816
6XuVE 159 4,79638
6Y0rU 157 5,75275
7bklW 149 9,06685
7ua7e 149 9,44915
eDiW 155 8,42694
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32797
2yPO8
 5731 47,1% 142 3.151E-47
2 phalp2_16834
1uDRT
 24 46,1% 143 1.514E-46
3 phalp2_17008
8jNgs
 3526 43,0% 144 3.883E-46
4 phalp2_7697
6I6lz
 232 49,6% 145 4.783E-45
5 phalp2_18518
6Rxhb
 4 41,5% 154 6.420E-39
6 phalp2_27968
RI1z
 5083 44,7% 143 1.201E-38
7 phalp2_32153
6Jjiu
 15 33,9% 153 1.643E-38
8 phalp2_7141
2F1c5
 58 44,8% 145 3.074E-38
9 phalp2_6928
2KMCh
 358 38,3% 159 7.865E-38
10 phalp2_9780
80F6A
 154 40,0% 140 7.865E-38

Domains

Domains [InterPro]
Disordered region
GH24
Representative sequence (used for alignment): 6RxcX (215 AA)
Member sequence: A0A6J5L0Y5 (141 AA)
1 215 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796192 [NCBI]
CDS location
range 3273 -> 3698
strand +
CDS
ATGAACGTCGTCGAGATGCTCAAGCGCGAGGAGGGCGTGCGCGCCTGCGTCTACCAGGACACGCTCGGCCTGTGGACGATCGGCTGCGGCCGCCTGGTGGACCCTAGCAAGCCCGGTGCCGGGCTGCGCCCGCGCGAGATCGACATGCTGCTCGCGAACGACATCAGCGACCGGGAGCAGGCGCTGCGCCTGTCACTGCCGTGGTTCGACACGCTGGACGAGGTCCGGCAGGCGGTGCTGGTGGGGATGGCCTTCCAGCTCGGGACGTCGTCCCTGATGGGCTTCACCAACACCCTCAACTTCGTGCGCGCCGGGCGCTGGCCCGAGGCCGCCACGGCCATGCTCGCGTCGAAGTGGGCCCAGCAAACACCCGCGCGCGCCCAGCGCATGGCGGACATGATGAGGACCGGCACGTGGACCCAATAA
CDS Source ID
[NCBI]
CDS Source
LR798218 [NCBI]
CDS location
range 21135 -> 21560
strand +
CDS
ATGAACGTCGTCGAGATGCTCAAGCGCGAGGAGGGCGTGCGCGCCTGCGTCTACCAGGACACGCTCGGCCTGTGGACGATCGGCTGCGGCCGCCTGGTGGACCCTAGCAAGCCCGGTGCCGGGCTGCGCCCGCGCGAGATCGACATGCTGCTCGCGAACGACATCAGCGACCGGGAGCAGGCGCTGCGCCTGTCACTGCCGTGGTTCGACACGCTGGACGAGGTCCGGCAGGCGGTGCTGGTGGGGATGGCCTTCCAGCTCGGGACGTCGTCCCTGATGGGCTTCACCAACACCCTCAACTTCGTGCGCGCCGGGCGCTGGCCCGAGGCCGCCACGGCCATGCTCGCGTCGAAGTGGGCCCAGCAAACACCCGCGCGCGCCCAGCGCATGGCGGACATGATGAGGACCGGCACGTGGACCCAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6RxcX) rather than this protein.
PDB ID
6RxcX
Method AlphaFoldv2
Resolution 78.70
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50