Protein

Protein accession
A0A6J5KJ55 [UniProt]
Representative
j9L3
Source
UniProt (cluster: phalp2_36335)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 84% (predicted by ML model)
Protein sequence
MLKWIILLVSCSLSYGGNMQISKKGLAQLAGEEGCCTAPYWDAAGGIWTFGIGITRYDAPPNPEDMEKGKDMKLDYCFSLFYKKLQKYVGEVNNHVHVEITQEQFDALVSFHYNTGSIGRATLTSIINNGRANEMSDDGVHTVAWNAFMMWVTPSAVRSRRVREANLFQYGRYELNGRVLITTADRHGHEHGAYEINALSYIDNIYPNTETNTSINEGDGGFVYSVGLSGVGQSVAGPWTAGTGLTTPPNSIDPDPTTGE
Physico‐chemical
properties
protein length:260 AA
molecular weight:28534,6 Da
isoelectric point:5,24
hydropathy:-0,31
Representative Protein Details
Accession
j9L3
Protein name
j9L3
Sequence length
380 AA
Molecular weight
41361,27940 Da
Isoelectric point
8,62021
Sequence
MKVSEQGFAEILSHEAIVPMPYRDSVNVWTVGVGHTKGAGAPDPAKLPRGVPMPLSECIEIFRNDLPKYEAGVNKALKVPVEQHVFDAMVSFHFNTGAIARAGFVSLINKGQAPSSEAVCNAMMQWSKPPEIVERRRKEMMLMKTGRYSKNPKIGVIQADAAGNVRWNTRKNISYAEAMGESISEPVTAARMIPQSDPVSMPATVADSEVVKRVQDLLKKRGYHFVGVSDGIMGPNTEAAIYAFRKANNLPPFDGTIDEKLIASLVGGEDKPVSPDRAEATVEQAAAKSEPVKAVTDQTWYSRLGAKILAIPAMIWAMVEGLLENIGIGKEKLAPFVEFFAAVPRWAYIAAIAGIAGWIWLSQNKAEKAQLEAFKDGKVN
Other Proteins in cluster: phalp2_36335
Total (incl. this protein): 5 Avg length: 340,0 Avg pI: 8,26
Protein ID Length (AA) pI
j9L3 380 8,62021
7cYwv 312 9,73036
99KN 365 7,97901
iJ4L 383 9,75047
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_21647
2V9bD
 9 31,8% 371 4.640E-38
2 phalp2_28471
1Y5Yk
 4 27,2% 371 5.683E-34
3 phalp2_9590
1qPJJ
 8 30,0% 280 8.809E-30
4 phalp2_38866
1Mo76
 29 30,7% 276 7.192E-29
5 phalp2_13759
6PI4E
 57 29,4% 360 1.434E-27
6 phalp2_24666
5IWY5
 127 31,3% 274 2.605E-27
7 phalp2_34307
3A2Hz
 178 25,6% 277 1.071E-23
8 phalp2_16965
86QY9
 61 28,7% 271 9.345E-21
9 phalp2_1642
8qFOb
 229 26,6% 281 7.814E-16
10 phalp2_22247
7g4te
 1 24,4% 294 1.040E-14

Domains

Domains [InterPro]
GH24
PG_1
Unannotated
Unannotated
Representative sequence (used for alignment): j9L3 (380 AA)
Member sequence: A0A6J5KJ55 (260 AA)
1 380 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959, PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796139 [NCBI]
CDS location
range 2772 -> 3554
strand -
CDS
ATGCTTAAATGGATAATATTATTAGTATCATGTTCTTTATCTTATGGGGGTAATATGCAAATATCTAAGAAAGGACTAGCACAGCTAGCAGGTGAGGAGGGCTGCTGTACAGCTCCTTATTGGGATGCTGCTGGTGGTATATGGACTTTTGGTATCGGTATAACTAGGTATGATGCTCCCCCTAATCCAGAAGATATGGAGAAAGGTAAAGACATGAAGTTAGACTATTGTTTCTCTCTCTTCTATAAGAAGCTACAGAAGTATGTAGGAGAAGTTAATAATCATGTGCATGTAGAGATAACACAAGAGCAATTCGACGCTCTAGTATCCTTCCATTATAATACAGGCTCTATTGGACGAGCTACGCTCACTAGTATTATTAATAACGGTAGAGCTAATGAAATGTCAGATGATGGAGTACATACTGTAGCCTGGAATGCTTTTATGATGTGGGTAACCCCTTCAGCAGTGAGATCTAGAAGAGTTAGAGAGGCTAATTTGTTTCAATACGGTAGATATGAGTTAAATGGTAGAGTACTTATAACTACTGCCGATAGGCATGGGCATGAGCATGGAGCCTATGAAATTAATGCTTTATCCTATATAGATAACATTTATCCTAATACTGAAACTAATACAAGCATTAATGAAGGAGATGGTGGATTTGTATATTCAGTAGGACTATCTGGAGTAGGACAATCTGTAGCAGGGCCATGGACTGCTGGTACGGGTTTAACTACTCCACCAAACTCTATTGATCCCGACCCAACTACCGGAGAATAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (j9L3) rather than this protein.
PDB ID
j9L3
Method AlphaFoldv2
Resolution 76.20
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50